{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:35:42Z","timestamp":1760060142528,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T00:00:00Z","timestamp":1754179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Introduction: Renal malacoplakia is a rare chronic granulomatous disease, often associated with immunosuppression and persistent Gram-negative infections, particularly Escherichia coli. Case Presentation: We present a case involving a 31-year-old woman with hypertension, gestational diabetes, and prior uterine curettage after labor induction for preeclampsia at 23 weeks. She developed urinary sepsis post-procedure. Imaging revealed bilateral nephromegaly, while laboratory tests showed acute kidney injury (KDIGO stage III), anemia, and thrombocytopenia. Blood and urine cultures grew Escherichia coli. Renal biopsy confirmed malacoplakia, demonstrating PAS-positive Michaelis\u2013Gutmann bodies and Von Hansemann cells. The patient responded to prolonged antibiotic therapy and supportive care. Discussion and Conclusion: This case highlights the importance of considering renal malacoplakia in patients with atypical urinary tract infections and nephromegaly, particularly in obstetric settings. Histopathological confirmation is essential, and timely treatment with intracellularly active antibiotics can lead to favorable outcomes. Early diagnosis is critical to prevent irreversible renal damage.<\/jats:p>","DOI":"10.3390\/clinpract15080143","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T09:41:17Z","timestamp":1754300477000},"page":"143","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Renal Malacoplakia Following Obstetric Intervention: A Rare Cause of Acute Kidney Injury in a Young Woman"],"prefix":"10.3390","volume":"15","author":[{"given":"Let\u00edcia Miyuki","family":"Ito","sequence":"first","affiliation":[{"name":"Paulista School of Medicina, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana Miki","family":"Oguma","sequence":"additional","affiliation":[{"name":"Paulista School of Medicina, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3020-1247","authenticated-orcid":false,"given":"Andr\u00e9 Kiyoshi","family":"Miyahara","sequence":"additional","affiliation":[{"name":"Paulista School of Medicina, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Aur\u00e9lio Sales","family":"da Veiga","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7788-8229","authenticated-orcid":false,"given":"Leandro","family":"Favaro","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Wesley","family":"de Godoy","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1rbara Antunes Bruno","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Ant\u00f4nio","family":"Moura","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelino de Souza","family":"Dur\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"},{"name":"Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo 05652-900, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0982-2484","authenticated-orcid":false,"given":"\u00c9rika Bevilaqua","family":"Rangel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Nephrology Division, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 04038-031, SP, Brazil"},{"name":"Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo 05652-900, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1053\/j.ajkd.2017.11.021","article-title":"Management of Acute Kidney Injury: Core Curriculum 2018","volume":"72","author":"Moore","year":"2018","journal-title":"Am. 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