{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:10:40Z","timestamp":1760425840373,"version":"build-2065373602"},"reference-count":15,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Background: Vitamin D deficiency (VDD) is highly prevalent in pediatric critically ill patients and is a potentially modifiable risk factor during critical illness. There are no established national or international recommendations for vitamin D supplementation in Pediatric Intensive Care Unit (PICU) patients. Objectives: This monocentric study aims to compare the practices regarding vitamin D supplementation before and after the introduction of a nutrition protocol (NP). Methods: We retrospectively analyzed vitamin D administration (time from PICU admission to initiation, amount of supplementation, accordance with existing guidelines) in children aged 0 to 16 who were admitted to the PICU of Lausanne University Hospital for more than 48 h the year before and the year after the introduction of a NP. Results: Vitamin D supplementation increased after NP introduction (95 IU per day more, p &lt; 0.0001). More patients received vitamin D during their stay (95% after vs. 77% before, p &lt; 0.0001). The dose adhered to NP recommendations for children under 12 and was higher for older children. According to Swiss guidelines for the general pediatric population, vitamin D supplementation was accurate in children under one year old before and after NP implementation. However, it was less than recommended for patients over one year old. Conclusions: The implementation of a NP significantly enhanced the scope of vitamin D supplementation. This study also highlights the practical limitations in meeting the recommended requirements with certain galenic formulations.<\/jats:p>","DOI":"10.3390\/clinpract15100186","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T05:48:21Z","timestamp":1760420901000},"page":"186","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of a Nutrition Protocol on Vitamin D Supplementation in a Pediatric Intensive Care Unit: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Maria","family":"P\u00e9rez Marin","sequence":"first","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6665-5291","authenticated-orcid":false,"given":"Vivianne","family":"Chanez","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8859-1399","authenticated-orcid":false,"given":"Guillaume","family":"Maitre","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7490-1384","authenticated-orcid":false,"given":"Laurence","family":"Boillat","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frida","family":"Rizzati","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline","family":"Lauwers","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6173-3396","authenticated-orcid":false,"given":"Maria-Helena","family":"Perez","sequence":"additional","affiliation":[{"name":"Pediatric Intensive Care Unit, Service of Paediatrics, Women-Mother-Children Department, Lausanne University Hospital, Rue Du Bugnon 21, 1011 Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.53738\/REVMED.2011.7.319.2332","article-title":"Vitamine D: Actualit\u00e9 et recommandations [Vitamin D: Update and recommendations]","volume":"7","author":"Amstutz","year":"2011","journal-title":"Rev. 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Nutr."}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-7283\/15\/10\/186\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T06:38:42Z","timestamp":1760423922000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/15\/10\/186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,13]]},"references-count":15,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["clinpract15100186"],"URL":"https:\/\/doi.org\/10.3390\/clinpract15100186","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,13]]}}}