{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T08:35:19Z","timestamp":1792398919689,"version":"4.4.0"},"reference-count":45,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Background\/Objectives: Gambling disorder (GD) is characterized by a high prevalence of co-occurring psychiatric disorders, including personality disorders (PDs), which may negatively influence clinical presentation, treatment outcomes, and relapse rates. The aim of this systematic review was to synthesize recent evidence regarding the association between GD and formally diagnosed PD and\/or diagnostically anchored PD symptomatology, and to describe the main personality dimension most frequently reported in affected individuals. Methods: A systematic search was conducted in the PubMed and Dialnet databases for articles published between 30 November 2015 and 30 November 2025, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines. PubMed was selected as the primary database because it is the most comprehensive source for peer-reviewed biomedical and psychiatric research, while Dialnet was included to complement PubMed by ensuring coverage of peer-reviewed psychiatric and psychological research published in other Romance-language journals, which are often underrepresented in international databases. The methodological quality and risk of bias of the included studies were evaluated using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for cross-sectional studies and the Newcastle\u2013Ottawa Scale (NOS) for observational studies. Data extraction and synthesis were performed manually by two independent reviewers. Eight studies, predominantly cross-sectional in nature, assessing exclusively formally diagnosed personality disorders in adult individuals (\u226518 years) diagnosed with GD were included. Results: Eight studies met the inclusion criteria, including a total of 4607 patients with GD. Across studies, personality pathology was highly prevalent among individuals with GD, with antisocial and borderline personality disorders most consistently reported. Elevated levels of impulsivity, emotional dysregulation, and narcissistic traits were frequently observed and were additionally associated with greater gambling severity, earlier onset, and poorer clinical outcomes. Antisocial personality symptoms were strongly linked to high-risk gambling subtypes, while obsessive\u2013compulsive personality traits showed a more heterogeneous relationship with gambling severity. Conclusions: These results underscore the importance of personality assessment in individuals with GD and highlight the need for longitudinal studies using standardized diagnostic frameworks to inform tailored prevention and treatment strategies.<\/jats:p>","DOI":"10.3390\/clinpract16010015","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:52:17Z","timestamp":1767963137000},"page":"15","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A Systematic Review of Personality Disorders in Patients with Gambling Disorder"],"prefix":"10.3390","volume":"16","author":[{"given":"Ioana","family":"Ioni\u021b\u0103","sequence":"first","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d Doctoral School, University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina Iuliana","family":"Mu\u0219at","sequence":"additional","affiliation":[{"name":"Experimental Research Center for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"},{"name":"Department of Scientific Research Methodology, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-8722","authenticated-orcid":false,"given":"Bogdan","family":"C\u0103t\u0103lin","sequence":"additional","affiliation":[{"name":"Experimental Research Center for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"},{"name":"Department of Physiology, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0741-6274","authenticated-orcid":false,"given":"Constantin Alexandru","family":"Ciobanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020022 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2520-5486","authenticated-orcid":false,"given":"Adela Magdalena","family":"Ciobanu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, \u201cProf. Dr. Alexandru Obregia\u201d Clinical Hospital of Psychiatry, 041914 Bucharest, Romania"},{"name":"Neuroscience Department, Discipline of Psychiatry, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.4309\/jgi.2009.23.4","article-title":"Gambling as a public health issue: The critical role of the local environment","volume":"23","author":"Marshall","year":"2009","journal-title":"J. Gambl. Issues"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e594","DOI":"10.1016\/S2468-2667(24)00126-9","article-title":"The prevalence of gambling and problematic gambling: A systematic review and meta-analysis","volume":"9","author":"Tran","year":"2024","journal-title":"Lancet Public Health"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"John, B., Holloway, K., Davies, N., May, T., Buhociu, M., Cousins, A.L., Thomas, S., and Roderique-Davies, G. (2020). Gambling Harm as a Global Public Health Concern: A Mixed Method Investigation of Trends in Wales. Front. Public Health, 8.","DOI":"10.3389\/fpubh.2020.00320"},{"key":"ref_4","first-page":"14","article-title":"Psychiatric Comorbidity Associated with Pathological Gambling","volume":"25","author":"Black","year":"2008","journal-title":"Psychiatry Times"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1556\/2006.7.2018.38","article-title":"Explaining the relation between pathological gambling and depression: Rumination as an underlying common cause","volume":"7","author":"Krause","year":"2018","journal-title":"J. Behav. Addict."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3928\/02793695-20250415-03","article-title":"Association Among Depressive Symptoms, Physical Symptoms, Serotonin Levels, and Gambling Disorder: A Case-Control Study","volume":"63","author":"Choi","year":"2025","journal-title":"J. Psychosoc. Nurs. Ment. Health Serv."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s10899-018-09825-w","article-title":"Struggling with Happiness: A Pathway Leading Depression to Gambling Disorder","volume":"35","author":"Rogier","year":"2019","journal-title":"J. Gambl. Stud."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jad.2014.06.023","article-title":"Bipolar disorder and gambling disorder comorbidity: Current evidence and implications for pharmacological treatment","volume":"167","author":"Pettorruso","year":"2014","journal-title":"J. Affect. Disord."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2147\/SAR.S83460","article-title":"A review of gambling disorder and substance use disorders","volume":"7","author":"Rash","year":"2016","journal-title":"Subst. Abus. Rehabil."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1177\/14034948211042249","article-title":"The relationship between substance use disorder and gambling disorder: A nationwide longitudinal health registry study","volume":"51","author":"Leino","year":"2023","journal-title":"Scand. J. Public Health"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1038\/s41386-019-0393-9","article-title":"Impulsivity in Gambling Disorder and problem gambling: A meta-analysis","volume":"44","author":"Ioannidis","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1034\/j.1600-0447.2003.00162.x","article-title":"Comorbidity of impulse control disorders in pathological gamblers","volume":"108","author":"Grant","year":"2003","journal-title":"Acta Psychiatry Scand."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Ford, M., and H\u00e5kansson, A. (2020). Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions: Opportunities for pathways to treatment. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0227644"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/inm.12221","article-title":"Impact of alcohol consumption on clinical aspects of gambling disorder","volume":"26","author":"Granero","year":"2017","journal-title":"Int. J. Ment. Health Nurs."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/YCO.0000000000000300","article-title":"Personality disorders and pathological gambling","volume":"30","author":"Vaddiparti","year":"2017","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.jpsychires.2007.11.007","article-title":"The association between gambling pathology and personality disorders","volume":"42","author":"Sacco","year":"2008","journal-title":"J. Psychiatry Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1521\/pedi.2008.22.2.191","article-title":"Personality disorders and pathological gambling: A review and re-examination of prevalence rates","volume":"22","author":"Bagby","year":"2008","journal-title":"J. Pers. Disord."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40473-013-0001-y","article-title":"Addictions and Personality Traits: Impulsivity and Related Constructs","volume":"1","author":"Mitchell","year":"2014","journal-title":"Curr. Behav. Neurosci. Rep."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Jauk, E., and Dieterich, R. (2019). Addiction and the Dark Triad of Personality. Front. Psychiatry, 10.","DOI":"10.3389\/fpsyt.2019.00662"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.paid.2016.02.049","article-title":"Pathological personality traits and emotion regulation difficulties","volume":"95","author":"Pollock","year":"2016","journal-title":"Pers. Individ. Differ."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0191-8869(98)00187-1","article-title":"Coping strategies in relation to personality disorders","volume":"26","author":"Bijttebier","year":"1999","journal-title":"Pers. Individ. Differ."},{"key":"ref_22","first-page":"279","article-title":"Evaluation of Adherence to Pharmacological Treatment in a Large Sample of Patients with Personality Disorder","volume":"22","author":"Cocchi","year":"2025","journal-title":"Clin. Neuropsychiatry"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Tani, F., Ponti, L., and Ghinassi, S. (2020). Sensation Seeking and Gambling Behavior in Adolescence: Can Externalizing Problems Moderate This Relationship?. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17238986"},{"key":"ref_24","unstructured":"Toneatto, T., and Nguyen, L. (2007). Individual characteristics and problem gambling behavior. Res. Meas. Issues Gambl. Stud., 279\u2013303."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1023\/A:1022005625498","article-title":"Gambling Behavior and Pathology in Relation to Impulsivity, Sensation Seeking, and Risky Behavior in Male College Students","volume":"14","author":"Langewisch","year":"1998","journal-title":"J. Gambl. Stud."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Kaur, P., Leino, T., Chegeni, R., Erevik, E.K., Mentzoni, R.A., and Pallesen, S. (2023). Association between problem gambling and personality traits: A longitudinal study among the general Norwegian population. Front. Psychol., 14.","DOI":"10.3389\/fpsyg.2023.1241365"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1037\/a0037413","article-title":"Personality and gambling involvement: A person-centered approach","volume":"28","author":"Savage","year":"2014","journal-title":"Psychol. Addict. Behav."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.psychres.2018.05.088","article-title":"Tempting fate: Chasing and maladaptive personality traits in gambling behavior","volume":"267","author":"Nigro","year":"2018","journal-title":"Psychiatry Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1017\/S1092852900016424","article-title":"Neuropsychological characteristics and personality traits in pathological gambling","volume":"13","author":"Forbush","year":"2008","journal-title":"CNS Spectr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s10899-022-10119-5","article-title":"The Association between the Five-factor Model of Personality and Problem Gambling: A Meta-analysis","volume":"39","author":"Dudfield","year":"2023","journal-title":"J. Gambl. Stud."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Moola, S., Tufanaru, C., Aromataris, E., Sears, K., Sfetc, R., Currie, M., Lisy, K., Qureshi, R., Mattis, P., and Mu, P.-F. (2020). Chapter 7: Systematic Reviews of Etiology and Risk, Joanna Briggs Institute.","DOI":"10.46658\/JBIRM-17-06"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1556\/2006.7.2018.50","article-title":"Gambling disorder and obsessive-compulsive personality disorder: A frequent but understudied comorbidity","volume":"7","author":"Medeiros","year":"2018","journal-title":"J. Behav. Addict."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Fierro, I., Fern\u00e1ndez-Prieto, R., Fern\u00e1ndez-Parra, A., Herrero-Mart\u00edn, M., and Herrero, A.J. (2024). Personality traits and physical activity in patients with gambling disorder attending a rehabilitation center. An observational study. Front. Psychol., 15.","DOI":"10.3389\/fpsyg.2024.1465195"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.psychres.2017.08.003","article-title":"Predictors of early dropout in treatment for gambling disorder: The role of personality disorders and clinical syndromes","volume":"257","author":"Maniaci","year":"2017","journal-title":"Psychiatry Res."},{"key":"ref_36","first-page":"424","article-title":"Gambling Disorder and Increased Psychiatric Comorbidity: A Finnish Register-Based Study","volume":"42","author":"Salonen","year":"2025","journal-title":"Nord. Alkohol. Nark."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10899-021-10011-8","article-title":"A Multi-Method Investigation of Normative and Pathological Personality Across the Spectrum of Gambling Involvement","volume":"38","author":"Quilty","year":"2022","journal-title":"J. Gambl. Stud."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s10899-018-9759-x","article-title":"Narcissistic Implications in Gambling Disorder: The Mediating Role of Emotion Dysregulation","volume":"34","author":"Rogier","year":"2018","journal-title":"J. Gambl. Stud."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s10899-016-9658-y","article-title":"Subtyping Non-treatment-seeking Problem Gamblers Using the Pathways Model","volume":"33","author":"Moon","year":"2017","journal-title":"J. Gambl. Stud."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s10899-021-10056-9","article-title":"Testing the Validity of the Pathways Model: A Latent Class Analysis of Potential Pathological Gambling Subtypes in a Non-Treatment Sample","volume":"38","author":"Black","year":"2022","journal-title":"J. Gambl. Stud."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1521\/pedi_2014_28_168","article-title":"The Prevalence of Comorbid Personality Disorders in Treatment-Seeking Problem Gamblers: A Systematic Review and Meta-Analysis","volume":"29","author":"Dowling","year":"2015","journal-title":"J. Pers. Disord."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1007\/s10899-014-9504-z","article-title":"The Application of an Etiological Model of Personality Disorders to Problem Gambling","volume":"31","author":"Brown","year":"2015","journal-title":"J. Gambl. Stud."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.jpsychires.2009.03.003","article-title":"Trait impulsivity and response inhibition in antisocial personality disorder","volume":"43","author":"Swann","year":"2009","journal-title":"J. Psychiatry Res."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.addbeh.2011.11.012","article-title":"Facets of impulsivity in the relationship between antisocial personality and abstinence","volume":"37","author":"Sargeant","year":"2012","journal-title":"Addict. Behav."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.biopsych.2007.06.018","article-title":"Personality disorders, behavioral disinhibition, and addiction: A commentary","volume":"62","author":"Pihl","year":"2007","journal-title":"Biol. Psychiatry"}],"container-title":["Clinics and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-7283\/16\/1\/15\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:57:47Z","timestamp":1767963467000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-7283\/16\/1\/15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,9]]},"references-count":45,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["clinpract16010015"],"URL":"https:\/\/doi.org\/10.3390\/clinpract16010015","relation":{},"ISSN":["2039-7283"],"issn-type":[{"value":"2039-7283","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,9]]}}}