{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T10:49:42Z","timestamp":1782730182025,"version":"3.54.5"},"reference-count":38,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinics and Practice"],"abstract":"<jats:p>Background and Objectives: Gambling disorder (GD) is a behavioral addiction associated with distress, comorbidity, and functional impairment. This exploratory cross-sectional study examined associations between DSM-5-TR symptom burden, personality dimensions, cognitive emotion regulation, quality of life, and sociodemographic variables in a Romanian clinical sample. Materials and Methods: The sample included 122 adults with psychiatrist-confirmed pathological gambling\/GD recruited from \u201cProf. Dr. Alexandru Obregia\u201d Clinical Hospital of Psychiatry, Bucharest. Personality was assessed with the Personality Clinical Form (PCF; 109 valid profiles), cognitive emotion regulation with the Cognitive Emotion Regulation Questionnaire, and quality of life with the Quality of Life Inventory. Symptom burden was measured using a nine-item binary DSM-5 symptom burden index. Results: The symptom burden index showed a pronounced ceiling effect: median = 9.00 (IQR = 9.00\u20139.00; range = 4\u20139), with 91.0% classified as severe and 77.9% meeting all nine criteria. In PCF analyses, symptom burden was positively associated, after Benjamini\u2013Hochberg correction, with broad personality pathology, including maladaptive personality dimensions, personality-functioning indicators, and personality-disorder feature scales; the strongest association involved borderline features. Catastrophizing and Blaming Others were positively associated with severity, whereas Positive Reappraisal, Putting into Perspective, and Positive Refocusing were negatively associated. Quality of life was very low overall and associated with personality and coping variables, but not directly with symptom burden. Criterion-count rank distributions differed by marital status and perceived social support; occupational status showed an omnibus distributional difference, but no pairwise contrast survived correction. Conclusions: GD was characterized by severe symptom burden and restricted score variability. Findings support multidimensional assessment of personality functioning, emotion regulation, quality of life, and social\u2013contextual vulnerability.<\/jats:p>","DOI":"10.3390\/clinpract16070122","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T08:45:20Z","timestamp":1782722720000},"page":"122","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploratory Associations of Personality Traits, Cognitive Emotion Regulation, and Quality of Life with DSM-Related Symptom Burden in Gambling Disorder"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5958-1095","authenticated-orcid":false,"given":"Ioana","family":"Ioni\u021b\u0103","sequence":"first","affiliation":[{"name":"\u201cCarol Davila\u201d Doctoral School, Faculty of Medicine, University of Medicine and Pharmacy, 050037 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina Iuliana","family":"Mu\u0219at","sequence":"additional","affiliation":[{"name":"Experimental Research Center for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"},{"name":"Department of Scientific Research Methodology, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-8722","authenticated-orcid":false,"given":"Bogdan","family":"C\u0103t\u0103lin","sequence":"additional","affiliation":[{"name":"Experimental Research Center for Normal and Pathological Aging, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"},{"name":"Department of Physiology, University of Medicine and Pharmacy of Craiova, 2 Petru Rare\u0219 Street, 200349 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5672-9394","authenticated-orcid":false,"given":"Dan Adrian","family":"Lutescu","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics and Biostatistics, Faculty of Dentistry, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050037 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0741-6274","authenticated-orcid":false,"given":"Constantin Alexandru","family":"Ciobanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020022 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2520-5486","authenticated-orcid":false,"given":"Adela Magdalena","family":"Ciobanu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, \u201cProf. Dr. Alexandru Obregia\u201d Clinical Hospital of Psychiatry, 041914 Bucharest, Romania"},{"name":"Neuroscience Department, Discipline of Psychiatry, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jpsychires.2022.12.031","article-title":"Gambling disorder duration and cognitive behavioural therapy outcome considering gambling preference and sex","volume":"158","author":"Lucas","year":"2023","journal-title":"J. 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