{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T14:15:23Z","timestamp":1783088123435,"version":"3.54.6"},"reference-count":45,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CMTR"],"abstract":"<jats:p>Craniomaxillofacial trauma (CMFt) poses a significant burden, yet in many countries the evidence base is fragmented across single-center hospital series without specialized registry. Using Chile as a case study, we demonstrate a dual-synthesis approach to construct a national CMFt profile. Six databases were searched through February 2026 (PROSPERO: CRD420261290860). Two reviewers independently screened studies. Risk of bias was assessed with the JBI critical appraisal tool. Fracture-site proportions were pooled via random-effects meta-analysis and synthesized using GRADE. DEIS trauma discharges (2001\u20132024) were analyzed with negative binomial interrupted time-series. Nineteen studies were included. CMFt represented 2.6\u20136.1% of emergency consultations. CMFt admissions were 54.2\/1000 trauma discharges; this rate dropped during 2020\u20132021 and rebounded post-2022. Pooled fracture-site distributions were highest for mandibular (45.3%) and zygomatic (24.2%) fractures. CMFt disproportionately affected males across both hospital series and national discharge data. According to DEIS, low-energy accidental injuries were the predominant etiology, followed by transport-related high-energy injuries and interpersonal violence, contrasting with hospital series where interpersonal violence predominated among adult surgical cohorts. Fracture admissions had longer length of stay (LOS) than soft-tissue CMFt (+0.94 days), with mean LOS ranging from 2.08 (nasal) to 8.35 days (multiple skull\/facial fractures). These findings support prioritizing surgical preparedness and training in common fracture patterns, while strengthening trauma surveillance, referral pathways, and service planning in health systems without dedicated CMFt registries.<\/jats:p>","DOI":"10.3390\/cmtr19030032","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T11:39:11Z","timestamp":1783078751000},"page":"32","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiology of Craniomaxillofacial Trauma in Chile: A Systematic Review and 24-Year Nationwide Interrupted Time-Series Analysis"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8959-3989","authenticated-orcid":false,"given":"Gustavo","family":"S\u00e1enz-Ravello","sequence":"first","affiliation":[{"name":"Center for Surveillance and Epidemiology of Oral Diseases (CEVEO), Faculty of Dentistry, University of Chile, Olivos 943, Independencia, Santiago 8380544, Chile"},{"name":"Servicio de Salud Tarapac\u00e1, Ministerio de Salud, Anibal Pinto 815, Iquique 1100527, Chile"},{"name":"School of Health and Wellbeing, Health Economics and Health Technology Assessment, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Carrasco Garc\u00eda","sequence":"additional","affiliation":[{"name":"Servicio de Salud Tarapac\u00e1, Ministerio de Salud, Anibal Pinto 815, Iquique 1100527, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"S\u00e1enz-Ravello","sequence":"additional","affiliation":[{"name":"School of Nursing, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago 8331150, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elda L.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Division of Plastic, Maxillofacial, and Oral Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"(2023). 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