{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T19:55:38Z","timestamp":1785527738623,"version":"3.56.0"},"reference-count":16,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,31]],"date-time":"2021-01-31T00:00:00Z","timestamp":1612051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Choroid plexus papilloma (CPP) is a rare brain tumour occurring mostly in infants and children. Most CPPs are intraventricular and present with symptoms and signs of increased intracranial pressure (ICP). This case report describes a middle-aged female who presented with spontaneous cerebrospinal fluid (CSF) rhinorrhea from a tumour located in the cerebellopontine angle (CPA). She underwent craniotomy with subtotal tumour resection and remained progression and rhinorrhea-free for several years. Upon clinical progression, the patient was treated with Cyberknife stereotactic radiosurgery. The patient clinically improved and demonstrated a favourable radiologic response to radiosurgery.<\/jats:p>","DOI":"10.3390\/curroncol28010073","type":"journal-article","created":{"date-parts":[[2021,1,31]],"date-time":"2021-01-31T21:31:56Z","timestamp":1612128716000},"page":"750-756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["CSF Rhinorrhea: A Rare Clinical Presentation of Choroid Plexus Papilloma"],"prefix":"10.3390","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0218-7270","authenticated-orcid":false,"given":"Layth","family":"Mula-Hussain","sequence":"first","affiliation":[{"name":"Radiation Oncology Division, The Ottawa Hospital\u2014University of Ottawa, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Malone","sequence":"additional","affiliation":[{"name":"Radiation Oncology Division, The Ottawa Hospital\u2014University of Ottawa, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlise P.","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, The Ottawa Hospital\u2014University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Neuro-Surgery Division, The Ottawa Hospital\u2014University of Ottawa, Ottawa, ON K1Y 4E9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn","family":"Malone","sequence":"additional","affiliation":[{"name":"Radiation Oncology Division, The Ottawa Hospital\u2014University of Ottawa, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,31]]},"reference":[{"key":"ref_1","first-page":"235","article-title":"Primary tumors of the choroid plexus. 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Neurol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s00701-019-03832-5","article-title":"Management of choroid plexus tumors\u2014An institutional experience","volume":"161","author":"Hosmann","year":"2019","journal-title":"Acta Neurochir."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1016\/S0140-6736(99)01744-4","article-title":"Radiation therapy and survival in choroid plexus carcinoma","volume":"353","author":"Wolff","year":"1999","journal-title":"Lancet"},{"key":"ref_7","unstructured":"Joseph, J.J., and Das, J.M. (2020). Choroid plexus papilloma. StatPearls [Internet], StatPearls Publishing."},{"key":"ref_8","unstructured":"Bullock, R., and Soares, D. (2009). Current Imaging of Cerebrospinal Fluid Leaks Im\u00e1genes M\u00e9dicas Actuales de P\u00e9rdidas de Fluido Cerebroespinal. West Indian Med. 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