{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T11:55:22Z","timestamp":1792670122011,"version":"4.5.0"},"reference-count":18,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:00:00Z","timestamp":1643500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Objective: To provide recommendations for a surveillance regimen that leads to the largest overall survival benefit for patients after curative treatment for Stage I\u2013IV colon and rectal cancer. Methods: Consistent with the Program in Evidence-Based Care\u2019s standard approach, guideline databases, i.e., MEDLINE, EMBASE, PubMed, Cochrane Library, and PROSPERO, were systematically searched. Then, we drafted recommendations and methodology experts performed an internal review of the resulting draft recommendations, which was followed by an external review by targeted experts and intended users. Results: Four systematic reviews and two randomized controlled trials were identified that provided evidence for recommendations. Conclusions: For patients with stage I\u2013III colon cancer, a medical history and physical examination should be performed every six months for three years; computed tomography (CT) of the chest-abdomen-pelvis (CT CAP) should be performed at one and three years, or one CT CAP could be performed at 18 months; the use of carcinoembryonic antigen (CEA) is optional if CT imaging is being performed; and surveillance colonoscopy should be performed one year after the initial surgery. The frequency of subsequent surveillance colonoscopy should be dictated by previous findings, but generally, colonoscopies should be performed every five years if the findings are normal. There was insufficient evidence to support these recommendations for patients with rectal cancer, Stage IV colon cancer, and patients over the age of 75 years. Patients should be informed of current recommendations and the treating physician should discuss the specific risks and benefits of each recommendation with their patients.<\/jats:p>","DOI":"10.3390\/curroncol29020062","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T01:46:08Z","timestamp":1643593568000},"page":"724-740","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["An Evidence-Based Guideline for Surveillance of Patients after Curative Treatment for Colon and Rectal Cancer"],"prefix":"10.3390","volume":"29","author":[{"given":"Erin","family":"Kennedy","sequence":"first","affiliation":[{"name":"Mount Sinai Hospital, 600 University Ave., Toronto, ON M5G 1X5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Zwaal","sequence":"additional","affiliation":[{"name":"Program in Evidence-Based Care, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Asmis","sequence":"additional","affiliation":[{"name":"Ottawa Hospital Cancer Centre, The Hospital General Campus, 501 Smyth Rd., Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Cho","sequence":"additional","affiliation":[{"name":"Southlake Regional Cancer Centre, 596 Davis Dr., Newmarket, ON L3Y 2P9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3072-2472","authenticated-orcid":false,"given":"Jacqueline","family":"Galica","sequence":"additional","affiliation":[{"name":"Queen\u2019s University Cancer Research Institute, Division of Cancer Care and Epidemiology, Queen\u2019s University, 92 Barrie Street, Kingston, ON K7L 3N6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Ginty","sequence":"additional","affiliation":[{"name":"Dorval Medical FHT, 465 Morden Rd., Oakville, ON L6K 3W6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Govindarajan","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital, 600 University Ave., Toronto, ON M5G 1X5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"E199","DOI":"10.1503\/cmaj.191292","article-title":"Projected estimates of cancer in Canada in 2020","volume":"192","author":"Brenner","year":"2020","journal-title":"Can. 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