{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:00:11Z","timestamp":1760238011124,"version":"build-2065373602"},"reference-count":35,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>In early 2017, the Canadian Partnership Against Cancer and CancerCare Manitoba undertook a comprehensive knowledge translation (KT) campaign to improve the utilization of single fraction radiotherapy (SFRT) over multiple fraction radiotherapy (MFRT) for palliative management of bone metastases. The campaign significantly increased short-term SFRT utilization. We assess the time-dependent effects of KT-derived SFRT utilization 12\u201324 months removed from the KT campaign in a Provincial Cancer Program. This study identified patients receiving palliative radiotherapy for bone metastases in Manitoba in the 2018 calendar year using the provincial radiotherapy database. The proportion of patients treated with SFRT in 2018 was compared to 2017. Logistic regression analyses identified risk factors associated with MFRT receipt. In 2018, 1008 patients received palliative radiotherapy for bone metastasis, of which 63.3% received SFRT, a small overall increase in SFRT use over 2017 (59.1%). However, 41.1% of ROs demonstrated year-over-year decreases in SFRT utilization, indicative of a time-dependent loss of SFRT prescription habits derived from KT. Although SFRT use increased slightly overall in 2018, evidence of compliance fatigue was observed, suggestive of a time-perishing property of RO prescription behaviours derived from KT methodologies. Verification of the study\u2019s findings in larger cohorts would be beneficial. These findings highlight the need for additional longitudinal KT reinforcement practices in the years following KT campaigns.<\/jats:p>","DOI":"10.3390\/curroncol29070404","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T05:37:53Z","timestamp":1658209073000},"page":"5097-5109","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Do Sustainable Palliative Single Fraction Radiotherapy Practices Proliferate or Perish 2 Years after a Knowledge Translation Campaign?"],"prefix":"10.3390","volume":"29","author":[{"given":"Shaheer","family":"Shahhat","sequence":"first","affiliation":[{"name":"Undergraduate Medical Education, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4719-854X","authenticated-orcid":false,"given":"Nikesh","family":"Hanumanthappa","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai 400053, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youn Tae","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Beck","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi","family":"Koul","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashir","family":"Bashir","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Cooke","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arbind","family":"Dubey","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Butler","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maged","family":"Nashed","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Hunter","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"},{"name":"Radiation Oncology, Western Manitoba Cancer Center, Brandon, MB R7A 2B3, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldrich D.","family":"Ong","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shrinivas","family":"Rathod","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Tran","sequence":"additional","affiliation":[{"name":"Canadian Partnership Against Cancer, Toronto, ON M5H 1J8, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0332-2024","authenticated-orcid":false,"given":"Julian O.","family":"Kim","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"},{"name":"CancerCare Manitoba Research Institute, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.radonc.2018.01.003","article-title":"Update of the systematic review of palliative radiation therapy fractionation for bone metastases","volume":"126","author":"Rich","year":"2018","journal-title":"Radiother. 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