{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:20:00Z","timestamp":1790713200596,"version":"4.1.0"},"reference-count":22,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Purpose: We describe our experience with the development of hepatobiliary infection in patients with prior surgical, percutaneous, or endoscopic biliary interventions who are receiving transarterial radioembolization (TARE) with yttrium-90 (90Y) for primary or metastatic hepatobiliary lesions. Methods: Records of 15 patients with a history of prior biliary intervention and liver malignancy subsequently treated with TARE at the participating medical center from November 2009 to September 2015 were reviewed. The primary endpoint was the development of a hepatic abscess or cholangitis in a patient after radioembolization. Results: A total of 15 patients comprising 9 men and 6 women, with a median age of 49 years (range 30\u201373), underwent 17 TARE with 90Y procedures. Of the 15 patients, 2 (13.3%) of them developed a hepatobiliary infection. A single patient (6.6%) developed a hepatobiliary abscess. Conclusion: Our study shows a low incidence rate of hepatic abscess following TARE in patients with prior biliary intervention.<\/jats:p>","DOI":"10.3390\/curroncol29100553","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T03:30:37Z","timestamp":1664335837000},"page":"7051-7058","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hepatic Abscess following Yttrium-90 Radioembolization in Patients with Surgical Bilioenteric Anastomosis or Compromised Sphincter of Oddi: A Tertiary Cancer Center Experience"],"prefix":"10.3390","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1031-5116","authenticated-orcid":false,"given":"Kevin N.","family":"Agahi","sequence":"first","affiliation":[{"name":"Department of Student Affairs, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0416-4566","authenticated-orcid":false,"given":"Armeen","family":"Mahvash","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed E.","family":"Abdelsalam","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1097\/01.RVI.0000236744.34720.73","article-title":"Radioembolization with yttrium-90 microspheres: A state-of-the-art brachytherapy treatment for primary and secondary liver malignancies: Part 3: Comprehensive literature review and future direction","volume":"17","author":"Salem","year":"2006","journal-title":"J. Vasc. Inter. Radiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jvir.2008.01.003","article-title":"Biliary sequelae following radioembolization with yttrium-90 microspheres","volume":"19","author":"Atassi","year":"2008","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1055\/s-0031-1280669","article-title":"Hepatic Radioembolization Complicated by Abscess","volume":"28","author":"Mascarenhas","year":"2011","journal-title":"Semin. Intervent. Radiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S1051-0443(07)61910-1","article-title":"Liver abscess after transcatheter oily chemoembolization for hepatic tumors: Incidence, predisposing factors, and clinical outcome","volume":"12","author":"Song","year":"2001","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_5","first-page":"55","article-title":"Clinical features of liver abscess developed after radiofrequency ablation and transarterial chemoembolization for hepatocellular carcinoma","volume":"12","author":"Kim","year":"2006","journal-title":"Korean J. Hepatol."},{"key":"ref_6","first-page":"2257","article-title":"Clinical and microbiological features of liver abscess after transarterial embolization for hepatocellular carcinoma","volume":"92","author":"Chen","year":"1997","journal-title":"Am. J. Gastroenterol."},{"key":"ref_7","first-page":"1436","article-title":"Liver abscess formation after local treatment of liver tumors","volume":"23","author":"Roche","year":"1996","journal-title":"Hepatology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/SLA.0b013e3181dbb7a7","article-title":"Liver-directed therapy for hepatic metastases in patients undergoing pancreaticoduodenectomy","volume":"252","author":"Farnell","year":"2010","journal-title":"Ann. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.2214\/ajr.184.6.01841860","article-title":"Liver abscess after percutaneous radiofrequency ablation for hepatocellular carcinomas: Frequency and risk factors","volume":"184","author":"Choi","year":"2005","journal-title":"Am. J. Roentgenol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1097\/01.RVI.0000099532.29957.4F","article-title":"Cholangitis and liver abscess after percutaneous ablation therapy for liver tumors: Incidence and risk factors","volume":"14","author":"Shibata","year":"2003","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1053\/j.tvir.2007.01.002","article-title":"Pre- and postoperative clinical care of patients undergoing interventional oncology procedures: A comprehensive approach to preventing and mitigating complications","volume":"9","author":"Georgiades","year":"2006","journal-title":"Tech. Vasc. Interv. Radiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S1051-0443(07)61577-2","article-title":"Risk Factors for Liver Abscess Formation after Hepatic Chemoembolization","volume":"12","author":"Kim","year":"2001","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S1051-0443(07)61959-9","article-title":"Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors","volume":"13","author":"Geschwind","year":"2002","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1097\/01.RVI.0000244854.79604.C1","article-title":"Effectiveness of an aggressive antibiotic regimen for chemoembolization in patients with previous biliary intervention","volume":"17","author":"Patel","year":"2006","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_15","first-page":"343","article-title":"Moxifloxacin prophylaxis for chemoembolization or embolization in patients with previous biliary interventions: A pilot study","volume":"197","author":"Khan","year":"2011","journal-title":"Am. J. Radiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1148\/radiographics.18.3.9599386","article-title":"Complications associated with transcatheter arterial embolization for hepatic tumors","volume":"18","author":"Sakamoto","year":"1998","journal-title":"Radiographics"},{"key":"ref_17","first-page":"1115","article-title":"Liver abscess formation after transarterial chemoembolization for malignant hepatic tumors","volume":"50","author":"Huang","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1097\/01.meg.0000108361.41221.8c","article-title":"Liver abscess complicating transcatheter arterial embolization: A rare but serious complication: A retrospective study after 3878 procedures","volume":"16","author":"Ong","year":"2004","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jvir.2010.10.014","article-title":"Pyogenic abscess after hepatic artery embolization: A rare but potentially lethal complication","volume":"22","author":"Mezhir","year":"2011","journal-title":"J. Vasc. Interv. Radiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1148\/radiol.2018170962","article-title":"90Y Radioembolization for hepatic malignancy in patients with previous biliary intervention: Multicenter analysis of hepatobiliary infections","volume":"288","author":"Devulapalli","year":"2018","journal-title":"Radiology"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2214\/ajr.145.1.115","article-title":"Hepatic embolization from the common hepatic artery using balloon occlusion technique","volume":"145","author":"Nakamura","year":"1985","journal-title":"Am. J. Roentgenol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jvir.2011.11.010","article-title":"Temporary balloon occlusion of the common hepatic artery for administration of Yttrium-90 resin microspheres in a patient with patent hepatoenteric collaterals","volume":"23","author":"Mahvash","year":"2012","journal-title":"J. Vasc. Interv. Radiol."}],"container-title":["Current Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1718-7729\/29\/10\/553\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:40:53Z","timestamp":1760143253000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1718-7729\/29\/10\/553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":22,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["curroncol29100553"],"URL":"https:\/\/doi.org\/10.3390\/curroncol29100553","relation":{},"ISSN":["1718-7729"],"issn-type":[{"value":"1718-7729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]}}}