{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:35:49Z","timestamp":1787981749297,"version":"build-2784847793"},"reference-count":58,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Orthopedic oncology has begun to use three-dimensional-printing technology, which is expected to improve the accuracy of osteotomies, ensure a safe margin, and facilitate precise surgery. However, several difficulties should be considered. Cadaver and clinical studies have reported more accurate osteotomies for bone-tumor resection using patient-specific cutting guides, especially in challenging areas such as the sacrum and pelvis, compared to manual osteotomies. Patient-specific cutting guides can help surgeons achieve resection with negative margins and reduce blood loss and operating time. Furthermore, this patient-specific cutting guide could be combined with more precise reconstruction using patient-specific implants or massive bone allografts. This review provides an overview of the basic technologies used in the production of patient-specific cutting guides and discusses their current status, advantages, and limitations. Moreover, we summarize cadaveric and clinical studies on the use of these guides in orthopedic oncology.<\/jats:p>","DOI":"10.3390\/curroncol30040292","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T04:45:35Z","timestamp":1680151535000},"page":"3859-3870","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Current Concepts in the Resection of Bone Tumors Using a Patient-Specific Three-Dimensional Printed Cutting Guide"],"prefix":"10.3390","volume":"30","author":[{"given":"Hisaki","family":"Aiba","sequence":"first","affiliation":[{"name":"Department of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy"},{"name":"Department of Orthopedic Surgery, Nagoya City University, Nagoya 467-8601, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetta","family":"Spazzoli","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8419-2008","authenticated-orcid":false,"given":"Shinji","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nara Medical University, Kashihara 634-8521, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas F.","family":"Mavrogenis","sequence":"additional","affiliation":[{"name":"First Department of Orthopedics, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Hermann","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy"},{"name":"Department of Tumors, HTC Hospital, Traumagologico Concepcion, 1580 San Martin, Concepcion 4030000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nagoya City University, Nagoya 467-8601, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nagoya City University, Nagoya 467-8601, Aichi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide Maria","family":"Donati","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4504-2867","authenticated-orcid":false,"given":"Costantino","family":"Errani","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"ref_1","first-page":"5512143","article-title":"Pelvic chondrosarcoma treated by en bloc resection with patient-specific osteotomy guides and reimplantation of the extracorporeally irradiated bone as an osseocartilaginous structural orthotopic autograft: A report of two cases with description of the surgical technique","volume":"2021","author":"Gkagkalis","year":"2021","journal-title":"Case. 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