{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T01:00:25Z","timestamp":1775696425443,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Metastatic prostate cancer is a common diagnosis with a protracted but terminal course. Gastrointestinal (GI) tract involvement is extremely rare, and reportedly portends a poor prognosis. It can present years after the initial prostate cancer diagnosis. Only fifteen cases of prostate cancer metastasis to the stomach have been reported in the literature. We report a case of a 72-year-old man with metastatic castration-resistant prostate cancer and extensive bony involvement. He presented a decade after the diagnosis of prostate cancer with signs of heartburn; a gastric biopsy was initially believed to represent primary gastric carcinoma, but subsequently a diagnosis of prostate cancer metastatic to the stomach was confirmed. This case highlights the importance of the provision of a pertinent clinical history and clinical differential diagnosis at the time of submission of surgical pathology specimens, as well as highlighting the need to have a low index of suspicion to pursue additional pathologic markers whenever a presumed second adenocarcinoma is noted in the context of a patient having a history of current or prior advanced-stage adenocarcinoma of another site. The correct diagnosis can shield the patient from the morbidity of inappropriate surgical or medical management.<\/jats:p>","DOI":"10.3390\/curroncol30040295","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T04:45:35Z","timestamp":1680151535000},"page":"3901-3914","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prostate Cancer Metastasis to Stomach: A Case Report and Review of Literature"],"prefix":"10.3390","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2079-2901","authenticated-orcid":false,"given":"Leena","family":"Moshref","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Abidullah","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Czaykowski","sequence":"additional","affiliation":[{"name":"Section of Hematology\/Oncology, Department of Internal Medicine, University of Manitoba and CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amitava","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Wightman","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Manitoba, Winnipeg, MB R3E 3P5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3152-2779","authenticated-orcid":false,"given":"Pamela","family":"Hebbard","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Manitoba, Winnipeg, MB R3E 0V9, Canada"},{"name":"Department of Surgical Oncology, CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"E601","DOI":"10.1503\/cmaj.212097","article-title":"Projected estimates of cancer in Canada in 2022","volume":"194","author":"Brenner","year":"2022","journal-title":"CMAJ"},{"key":"ref_2","unstructured":"(2018). 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