{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T22:43:30Z","timestamp":1785019410526,"version":"3.55.0"},"reference-count":23,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T00:00:00Z","timestamp":1691971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute of General Medical Sciences","award":["5R01GM137656-02"],"award-info":[{"award-number":["5R01GM137656-02"]}]},{"name":"National Institute of General Medical Sciences","award":["5P01CA236778-02 5266"],"award-info":[{"award-number":["5P01CA236778-02 5266"]}]},{"name":"National Cancer Institute","award":["5R01GM137656-02"],"award-info":[{"award-number":["5R01GM137656-02"]}]},{"name":"National Cancer Institute","award":["5P01CA236778-02 5266"],"award-info":[{"award-number":["5P01CA236778-02 5266"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Sarcomas are a rare tumor of mesenchymal origin. The liposarcoma is the most common sarcoma of the retroperitoneum. Liposarcomas are typically low grade, and present at an advanced stage and a large size. We report a case of a large retroperitoneal liposarcoma, approximately 50 kg, encasing both kidneys, which was managed via a two-stage resection and staged renal auto-transplantation into the intra-peritoneal pelvis. The patient maintained normal renal function throughout, and remains disease free two years post-resection. Renal auto-transplantation with pelvic placement may facilitate improved margin-free resection. Renal relocation may allow the use of curative-intent ablative therapies such as radiofrequency ablation and radiation in cases of retroperitoneal recurrence.<\/jats:p>","DOI":"10.3390\/curroncol30080552","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T12:35:25Z","timestamp":1692016525000},"page":"7620-7626","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bilateral Renal Auto-Transplantation for Retroperitoneal Sarcomas: Is It Underutilized?"],"prefix":"10.3390","volume":"30","author":[{"given":"Tyler P.","family":"Robinson","sequence":"first","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Milgrom","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"},{"name":"Providence Saint John\u2019s Cancer Institute, Santa Monica, CA 90404, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Nagaraju","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"},{"name":"Renal Transplant Division, Charleston Area Medical Center, Charleston, WV 25301, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William C.","family":"Goggins","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kannan P.","family":"Samy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"},{"name":"Department of Surgery, Duke University Medical Center, Durham, NC 27707, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonidas G.","family":"Koniaris","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA"},{"name":"Department of Surgery, Oregon Health and Science University, Portland, OR 97239, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,14]]},"reference":[{"key":"ref_1","first-page":"2597","article-title":"Incidence and survival in sarcoma in the United States: A focus on musculoskeletal lesions","volume":"33","author":"Ng","year":"2013","journal-title":"Anticancer Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/PAP.0000000000000284","article-title":"The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities","volume":"28","author":"Choi","year":"2021","journal-title":"Adv. Anat Pathol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21654","article-title":"Cancer Statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/SLA.0b013e3181e49000","article-title":"Prognostication for trunk and retroperitoneal sarcomas","volume":"252","author":"Koniaris","year":"2010","journal-title":"Ann. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e465","DOI":"10.1111\/ajco.12769","article-title":"Clinical benefit and residual kidney function of en bloc nephrectomy for perirenal retroperitoneal sarcoma","volume":"14","author":"Cho","year":"2018","journal-title":"Asia Pac. J. Clin. Oncol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1097\/SLA.0000000000001447","article-title":"Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group","volume":"263","author":"Gronchi","year":"2016","journal-title":"Ann. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"7873","DOI":"10.1245\/s10434-021-09654-z","article-title":"Management of Primary Retroperitoneal Sarcoma (RPS) in the Adult: An Updated Consensus Approach from the Transatlantic Australasian RPS Working Group","volume":"28","author":"Swallow","year":"2021","journal-title":"Ann. Surg. Oncol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"88","DOI":"10.21037\/tgh.2018.10.12","article-title":"Integrating therapies for surgical adult soft tissue sarcoma patients","volume":"3","author":"Milgrom","year":"2018","journal-title":"Transl. Gastroenterol. Hepatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jss.2007.02.026","article-title":"Outcomes for soft-tissue sarcoma in 8249 cases from a large state cancer registry","volume":"141","author":"Gutierrez","year":"2007","journal-title":"J. Surg. Res."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/BF02305556","article-title":"Nephrectomy during operative management of retroperitoneal sarcoma","volume":"4","author":"Russo","year":"1997","journal-title":"Ann. Surg. Oncol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/jso.24875","article-title":"Effect of nephrectomy for retroperitoneal sarcoma on post-operative renal function","volume":"117","author":"Kim","year":"2018","journal-title":"J. Surg. Oncol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1245\/s10434-020-09290-z","article-title":"Renal Function After Retroperitoneal Sarcoma Resection with Nephrectomy: A Matched Analysis of the United States Sarcoma Collaborative Database","volume":"28","author":"Stahl","year":"2021","journal-title":"Ann. Surg. Oncol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s00268-017-4157-6","article-title":"Radical Nephrectomy for Primary Retroperitoneal Liposarcoma Near the Kidney has a Beneficial Effect on Disease-Free Survival","volume":"42","author":"Rhu","year":"2018","journal-title":"World J. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.eururo.2013.06.044","article-title":"Renal function after nephron-sparing surgery versus radical nephrectomy: Results from EORTC randomized trial 30904","volume":"65","author":"Scosyrev","year":"2014","journal-title":"Eur. Urol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1111\/j.1600-6143.2011.03945.x","article-title":"Multivisceral Ex Vivo Surgery for Tumors Involving Celiac and Superior Mesenteric Arteries","volume":"12","author":"Kato","year":"2012","journal-title":"Am. J. Transplant."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1097\/SLA.0000000000002250","article-title":"Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group","volume":"267","author":"MacNeill","year":"2018","journal-title":"Ann. Surg."},{"key":"ref_17","first-page":"9725169","article-title":"Wide Excision of a Retroperitoneal Liposarcoma with En Bloc Ureterectomy and Renal Salvage by Autotransplantation","volume":"2019","author":"Paloyo","year":"2019","journal-title":"Case Rep. Transplant."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/jso.24041","article-title":"Inferior vena cava reconstruction for leiomyosarcoma of Zone I-III requiring complete hepatectomy and bilateral nephrectomy with autotransplantation","volume":"112","author":"Fernandez","year":"2015","journal-title":"J. Surg. Oncol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s12262-012-0474-z","article-title":"Giant retroperitoneal liposarcoma- renal salvage by autotransplantation","volume":"75","author":"Bansal","year":"2013","journal-title":"Indian J. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0039-6060(97)90179-3","article-title":"Radical resection of tumors of the inferior vena cava with vascular reconstruction and kidney autotransplantation","volume":"121","author":"Kraybill","year":"1997","journal-title":"Surgery"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/annonc\/mdq285","article-title":"Histology-driven chemotherapy of soft-tissue sarcoma","volume":"21","author":"Eriksson","year":"2010","journal-title":"Ann. Oncol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/S1470-2045(20)30446-0","article-title":"Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): A multicentre, open-label, randomised, phase 3 trial","volume":"21","author":"Bonvalot","year":"2020","journal-title":"Lancet Oncol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.yasu.2015.04.002","article-title":"Principles in Management of Soft Tissue Sarcoma","volume":"49","author":"Crago","year":"2015","journal-title":"Adv. Surg."}],"container-title":["Current Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1718-7729\/30\/8\/552\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:33:03Z","timestamp":1760128383000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1718-7729\/30\/8\/552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,14]]},"references-count":23,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["curroncol30080552"],"URL":"https:\/\/doi.org\/10.3390\/curroncol30080552","relation":{},"ISSN":["1718-7729"],"issn-type":[{"value":"1718-7729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,14]]}}}