{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:38:22Z","timestamp":1787027902920,"version":"build-2736575974"},"reference-count":41,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Background: A previous systematic review by our team (2012) undertook comprehensive geriatric assessment (CGA) in breast cancer and concluded there was not sufficient evidence to instate CGA as mandatory practice. SIOG\/EUSOMA guidelines published in 2021 advocate the use of CGA in breast cancer patients. The aim is to perform an updated systematic review of the literature. Methods: A systematic review of studies published between 2012 and 2022 that assessed the use of CGA in breast cancer was performed on Cochrane, PubMed and Embase. Results: A total of 18 articles including 4734 patients with breast cancer were identified. The studies covered four themes for use of CGA in breast cancer: (1) to determine factors influencing survival (2) as an adjunct to treatment decision-making (3) to measure quality of life, and (4) to determine which tools should be included. There was evidence to support the use of CGA in themes 1\u20133; however, it is uncertain which assessment tools are best to use (theme 4). Conclusions: CGA can be used to determine factors affecting survival and quality of life in breast cancer patients and can therefore be used to aid treatment decision-making. Further work is required to determine gold standard CGA.<\/jats:p>","DOI":"10.3390\/curroncol30090602","type":"journal-article","created":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T08:01:30Z","timestamp":1694160090000},"page":"8294-8309","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comprehensive Geriatric Assessment for Older Women with Early-Stage (Non-Metastatic) Breast Cancer\u2014An Updated Systematic Review of the Literature"],"prefix":"10.3390","volume":"30","author":[{"given":"Chantae","family":"Reid-Agboola","sequence":"first","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Klukowska","sequence":"additional","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca L.","family":"Malcolm","sequence":"additional","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cora","family":"Harrison","sequence":"additional","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"Royal Free Hospital, Royal Free London NHS Foundation Trust, London NW3 2QG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3832-7431","authenticated-orcid":false,"given":"Ruth M.","family":"Parks","sequence":"additional","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2973-0755","authenticated-orcid":false,"given":"Kwok-Leung","family":"Cheung","sequence":"additional","affiliation":[{"name":"Nottingham Breast Cancer Research Centre, University of Nottingham, Nottingham NG7 2UH, UK"},{"name":"School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,7]]},"reference":[{"key":"ref_1","unstructured":"Office for National Statistics (2021, July 29). 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