{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:43:47Z","timestamp":1760150627853,"version":"build-2065373602"},"reference-count":8,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:00:00Z","timestamp":1703116800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Mediastinal germ cell tumors (GCTs) are rare. Post-chemotherapy residual masses in patients with a nonseminomatous GCT require resection. A patient with a large mediastinal GCT involving the left subclavian artery, superior vena cava (SVC) and hilum of the right lung is presented. Despite a biochemical response to chemotherapy, the tumor enlarged on serial imaging. With guidance from medical oncology, a multidisciplinary surgical team, including cardiac anesthesia, cardiac surgery and thoracic surgery resected the tumor with a staged reconstruction of the SVC. The procedure was well tolerated and yielded clear margins. The final pathology showed a significant associated component of rhabdomyosarcoma.<\/jats:p>","DOI":"10.3390\/curroncol31010003","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T05:36:12Z","timestamp":1703136972000},"page":"42-49","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Resection of a Large Growing Mediastinal Germ Cell Tumor Using a Multidisciplinary Approach"],"prefix":"10.3390","volume":"31","author":[{"given":"Alison","family":"Greene","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2405-0216","authenticated-orcid":false,"given":"Lori","family":"Wood","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Department of Medicine, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Champion","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Department of Medicine, Dalhousie University, Queen Elizabeth Hospital, Charlottetown, PEI C1A 8T5, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Castonguay","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Scheffler","sequence":"additional","affiliation":[{"name":"Division of Cardiac Anesthesia, Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Deshaies","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Wood","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"French","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Department of Surgery, Dalhousie University, Queen Elizabeth II Hospital, Halifax, NS B3H 2Y9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3390\/curroncol28010010","article-title":"Primary mediastinal germ cell tumors\u2014The university of western Ontario experience","volume":"28","author":"Lavi","year":"2020","journal-title":"Curr. 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