{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:23:49Z","timestamp":1793039029028,"version":"4.5.0"},"reference-count":101,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T00:00:00Z","timestamp":1727827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>The frequency of long-term urination dysfunction after surgery for rectal cancer remains unclear, yet it is essential to establish this to improve treatment strategies. Randomized controlled trials (RCTs), non-RCTs, and cohort studies were included with patients having undergone sphincter-preserving total (TME) or partial mesorectal excision (PME) for the treatment of primary rectal cancer in this review. The outcome was urination dysfunction reported at least three months postoperatively, both overall urination dysfunction and subdivided into specific symptoms. The online databases PubMed, Embase, and Cochrane CENTRAL were searched, bias was assessed using the Newcastle\u2013Ottawa scale, and results were synthesized using one-group frequency meta-analyses. A total of 55 studies with 15,072 adults were included. The median follow-up was 29 months (range 3\u2013180). The pooled overall urination dysfunction was 21% (95% confidence interval (CI) 12%\u201330%) 3\u201311 months postoperatively and 25% (95% CI 19%\u201332%) \u226512 months postoperatively. Retention and incontinence were common 3\u201311 months postoperatively, with pooled frequencies of 11% and 14%, respectively. Increased urinary frequency, retention, and incontinence seemed even more common \u226512 months postoperatively, with pooled frequencies of 37%, 20%, and 23%, respectively. In conclusion, one in five patients experienced urination dysfunction more than a year following an operation for rectal cancer.<\/jats:p>","DOI":"10.3390\/curroncol31100442","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T06:27:31Z","timestamp":1727850451000},"page":"5929-5942","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Frequency of Urination Dysfunction in Patients Operated on for Rectal Cancer: A Systematic Review with Meta-Analyses"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6108-9701","authenticated-orcid":false,"given":"Dagn\u00fd Halla","family":"\u00c1g\u00fastsd\u00f3ttir","sequence":"first","affiliation":[{"name":"Center for Perioperative Optimization and Copenhagen Sequelae Center CARE, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stina","family":"\u00d6berg","sequence":"additional","affiliation":[{"name":"Center for Perioperative Optimization and Copenhagen Sequelae Center CARE, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-7898","authenticated-orcid":false,"given":"Camilla","family":"Christophersen","sequence":"additional","affiliation":[{"name":"Center for Perioperative Optimization and Copenhagen Sequelae Center CARE, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5722-4393","authenticated-orcid":false,"given":"Birthe Thing","family":"Oggesen","sequence":"additional","affiliation":[{"name":"Center for Perioperative Optimization and Copenhagen Sequelae Center CARE, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0063-1086","authenticated-orcid":false,"given":"Jacob","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Center for Perioperative Optimization and Copenhagen Sequelae Center CARE, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.ejso.2005.05.002","article-title":"Improved survival in cancer of the colon and rectum in Sweden","volume":"31","author":"Birgisson","year":"2005","journal-title":"Eur. 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