{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:13:57Z","timestamp":1793124837514,"version":"4.5.0"},"reference-count":27,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T00:00:00Z","timestamp":1733529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Ovarian cancer (OC) is diagnosed at a locally advanced stage in two-thirds of cases. The first line of treatment consists of cytoreductive surgery (CRS) combined with neoadjuvant and\/or adjuvant chemotherapy. However, CRS can be associated with high rates of postoperative complications (POCs), and detection of fragile patients at high risk of POCs is important. The American College of Surgeons Surgical Risk Calculator (ACS-SRC) provides a predictive model for early POCs (30 days) for any given surgical procedure. This study aimed to evaluate the performance of the ACS-SRC in predicting the occurrence of early POCs for patients undergoing CRS for OC. This was a retrospective study that included patients undergoing CRS for advanced OC between January 2010 and December 2022. Early POCs were reviewed, and the rate of POCs was compared with those predicted by the ACS-SRC to evaluate its accuracy (i.e., discrimination and calibration). A total of 218 patients were included, 112 of whom underwent extensive surgery\/resection. A total of 94 complications were recorded. This cohort demonstrated correct calibration of the ACS-SRC for the prediction of surgical site infection, readmission, and the need for nursing care post-discharge (NCPD; transfer to revalidation center or need for nursing care at home). Using both the discrimination and calibration methods, the score only predicted NCPD. In this study, the ACS-SRC was shown to be of little value for patients undergoing cytoreductive surgery for ovarian peritoneal carcinomatosis, as it only accurately predicted NCPD.<\/jats:p>","DOI":"10.3390\/curroncol31120579","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T12:22:06Z","timestamp":1733833326000},"page":"7863-7871","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of the American College of Surgeons Surgical Risk Calculator (ACS-SRC) for Prediction of Early Postoperative Complications in Patients Undergoing Cytoreductive Surgery for Ovarian Peritoneal Carcinomatosis"],"prefix":"10.3390","volume":"31","author":[{"given":"Cedric","family":"Kabeya","sequence":"first","affiliation":[{"name":"Department of Digestive Surgery and Digestive Surgical Oncology, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7498-3677","authenticated-orcid":false,"given":"Charif","family":"Khaled","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery and Digestive Surgical Oncology, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Polastro","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Moreau","sequence":"additional","affiliation":[{"name":"Department of Statistics, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Bucella","sequence":"additional","affiliation":[{"name":"Department of Gynecology, CHU Saint-Pierre, Universit\u00e9 Libre de Bruxelles (ULB), Rue aux Laines 105, 1000 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Fastrez","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8051-1588","authenticated-orcid":false,"given":"Gabriel","family":"Liberale","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery and Digestive Surgical Oncology, Jules Bordet Institute, The Brussels University Hospital (H.U.B), Universit\u00e9 Libre de Bruxelles (ULB), Meylemeersch Street 90, 1070 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/ijgo.13878","article-title":"Cancer of the Ovary, Fallopian Tube, and Peritoneum: 2021 Update","volume":"155","author":"Berek","year":"2021","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Pecorino, B., Lagan\u00e0, A.S., Chiantera, V., Ferrara, M., Stefano, A.B.D., Donna, M.C.D., Sorrentino, F., Nappi, L., Miku\u0161, M., and Scollo, P. (2022). Progression Free Survival, Overall Survival, and Relapse Rate in Endometrioid Ovarian Cancer and Synchronous Endometrial-Ovarian Endometrioid Cancer (SEO-EC): Results from a Large Retrospective Analysis. Medicina, 58.","DOI":"10.3390\/medicina58121706"},{"key":"ref_3","unstructured":"(2024, September 20). Cancer of the Ovary\u2014Cancer Stat Facts, Available online: https:\/\/seer.cancer.gov\/statfacts\/html\/ovary.html."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1515\/pp-2022-0199","article-title":"Prognostic Value of Preoperative Serological Biomarkers in Patients Undergoing Cytoreductive Surgery for Ovarian Cancer Peritoneal Metastases","volume":"8","author":"Khaled","year":"2023","journal-title":"Pleura Peritoneum"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"102074","DOI":"10.1016\/j.canep.2021.102074","article-title":"Ovarian Cancer Survival by Stage, Histotype, and Pre-Diagnostic Lifestyle Factors, in the Prospective UK Million Women Study","volume":"76","author":"Gaitskell","year":"2022","journal-title":"Cancer Epidemiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/S0140-6736(18)32552-2","article-title":"Epithelial Ovarian Cancer","volume":"393","author":"Lheureux","year":"2019","journal-title":"Lancet"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jviscsurg.2019.12.002","article-title":"A Radical Approach to Achieve Complete Cytoreductive Surgery Improve Survival of Patients with Advanced Ovarian Cancer","volume":"157","author":"Liberale","year":"2020","journal-title":"J. Visc. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3892\/ol.2022.13274","article-title":"Risk Factors of Perioperative Complications and Management with Enhanced Recovery after Primary Surgery in Women with Epithelial Ovarian Carcinoma in a Single Center","volume":"23","author":"Li","year":"2022","journal-title":"Oncol. Lett."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.ygyno.2020.11.021","article-title":"Advanced Ovarian Cancer and Cytoreductive Surgery: Independent Validation of a Risk-Calculator for Perioperative Adverse Events","volume":"160","author":"Straubhar","year":"2021","journal-title":"Gynecol. Oncol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1245\/ASO.2006.08.021","article-title":"A Laparoscopy-Based Score to Predict Surgical Outcome in Patients with Advanced Ovarian Carcinoma: A Pilot Study","volume":"13","author":"Fagotti","year":"2006","journal-title":"Ann. Surg. Oncol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"839","DOI":"10.21873\/invivo.11846","article-title":"The Influence of the Preoperative Status on the Risk of Postoperative Complications After Cytoreductive Surgery for Advanced-Stage Ovarian Cancer","volume":"34","author":"Bacalbasa","year":"2020","journal-title":"In Vivo"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.jamcollsurg.2013.07.385","article-title":"Development and Evaluation of the Universal ACS NSQIP Surgical Risk Calculator: A Decision Aid and Informed Consent Tool for Patients and Surgeons","volume":"217","author":"Bilimoria","year":"2013","journal-title":"J. Am. Coll. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1016\/j.ejso.2021.05.019","article-title":"Peritoneal Cancer Index Predicts Severe Complications after Ovarian Cancer Surgery","volume":"47","author":"Lomnytska","year":"2021","journal-title":"Eur. J. Surg. Oncol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Rafii, A., Stoeckle, E., Jean-Laurent, M., Ferron, G., Morice, P., Houvenaeghel, G., Lecuru, F., Leblanc, E., and Querleu, D. (2012). Multi-Center Evaluation of Post-Operative Morbidity and Mortality after Optimal Cytoreductive Surgery for Advanced Ovarian Cancer. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0039415"},{"key":"ref_15","unstructured":"(2024, August 30). ACS Risk Calculator\u2014Patient Information. Available online: https:\/\/riskcalculator.facs.org\/RiskCalculator\/PatientInfo.jsp."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"571.e1","DOI":"10.1016\/j.ajog.2019.02.019","article-title":"Development and Validation of a Risk-Calculator for Adverse Perioperative Outcomes for Women with Ovarian Cancer","volume":"220","author":"Cham","year":"2019","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/jso.27046","article-title":"The Efficacy of the American College of Surgeons Surgical Risk Calculator in the Prediction of Postoperative Complications in Oncogeriatric Patients after Curative Surgery for Abdominal Tumors","volume":"126","author":"Hafez","year":"2022","journal-title":"J. Surg. Oncol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1136\/ijgc-2021-002772","article-title":"Predictive Validity of American College of Surgeons: National Surgical Quality Improvement Project Risk Calculator in Patients with Ovarian Cancer Undergoing Interval Debulking Surgery","volume":"31","author":"Cathcart","year":"2021","journal-title":"Int. J. Gynecol. Cancer"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.ygyno.2017.03.020","article-title":"Trends and Factors Associated with Radical Cytoreductive Surgery in the United States: A Case for Centralized Care","volume":"145","author":"Sinno","year":"2017","journal-title":"Gynecol. Oncol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ygyno.2016.02.015","article-title":"Evaluation of the Performance of the ACS NSQIP Surgical Risk Calculator in Gynecologic Oncology Patients Undergoing Laparotomy","volume":"141","author":"Rivard","year":"2016","journal-title":"Gynecol. Oncol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1001\/jama.2017.12126","article-title":"Discrimination and Calibration of Clinical Prediction Models: Users\u2019 Guides to the Medical Literature","volume":"318","author":"Alba","year":"2017","journal-title":"JAMA"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/aogs.14355","article-title":"Complications after Advanced Ovarian Cancer Surgery-A Population-Based Cohort Study","volume":"101","author":"Palmqvist","year":"2022","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/IGC.0000000000000378","article-title":"Evaluation of the National Surgical Quality Improvement Program Universal Surgical Risk Calculator for a Gynecologic Oncology Service","volume":"25","author":"Szender","year":"2015","journal-title":"Int. J. Gynecol. Cancer"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/EDE.0b013e3181c30fb2","article-title":"Assessing the Performance of Prediction Models: A Framework for Some Traditional and Novel Measures","volume":"21","author":"Steyerberg","year":"2010","journal-title":"Epidemiology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ygyno.2009.03.018","article-title":"Improved Progression-Free and Overall Survival in Advanced Ovarian Cancer as a Result of a Change in Surgical Paradigm","volume":"114","author":"Chi","year":"2009","journal-title":"Gynecol. Oncol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.3802\/jgo.2022.33.e53","article-title":"Factors Predicting Postoperative Morbidity after Cytoreductive Surgery for Ovarian Cancer: A Systematic Review and Meta-Analysis","volume":"33","author":"Kengsakul","year":"2022","journal-title":"J. Gynecol. Oncol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ygyno.2016.04.020","article-title":"A Laparoscopic Risk-Adjusted Model to Predict Major Complications after Primary Debulking Surgery in Ovarian Cancer: A Single-Institution Assessment","volume":"142","author":"Vizzielli","year":"2016","journal-title":"Gynecol. Oncol."}],"container-title":["Current Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1718-7729\/31\/12\/579\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:49:34Z","timestamp":1760114974000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1718-7729\/31\/12\/579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,7]]},"references-count":27,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["curroncol31120579"],"URL":"https:\/\/doi.org\/10.3390\/curroncol31120579","relation":{},"ISSN":["1718-7729"],"issn-type":[{"value":"1718-7729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,7]]}}}