{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T08:15:42Z","timestamp":1769588142063,"version":"3.49.0"},"reference-count":14,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Landesarbeitsgemeinschaft Onkologische Versorgung Brandenburg e.V. (LAGO)"},{"name":"Medizinische Hochschule Brandenburg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Background: Medical care structures differ between urban and rural areas. Clinical cancer registries can depict real-world care through detailed data analysis, identifying potential regional disparities and contributing to improvements in healthcare. Methods: Data from the Brandenburg\u2013Berlin Clinical-Epidemiological Cancer Registry for the years of diagnosis 2017\u20132022 were analyzed to assess the epidemiology and real-world care of gastric cancer, including cardia. Brandenburg was compared to Berlin regarding perioperative treatment regimens. The resulting survival benefits were assessed using Kaplan\u2013Meier and Cox regression models. Results: For the years of diagnosis 2017 to 2022, 5805 cases of gastric carcinoma were documented in the cancer registry. Survival data showed no significant differences between Berlin and Brandenburg. Preoperative therapy for cT3\/cT4N0 tumors was significantly more common in Berlin (72%) than in Brandenburg (68%). Perioperative therapy was associated with a survival benefit for stages T3-\/T4N+ but not for stages T1N+ or T2. The lower proportion of pre-treated T3\/T4N+ patients in rural Brandenburg did not result in a significant survival difference. Conclusions: The data provide a comprehensive representation of the current state of gastric cancer care in these two regions. Gastric cancer treatment outcomes, in terms of survival, are comparable between the rural region of Brandenburg and the urban center of Berlin.<\/jats:p>","DOI":"10.3390\/curroncol32040228","type":"journal-article","created":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T03:59:06Z","timestamp":1744689546000},"page":"228","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Gastric Cancer in the Countryside or in the City: Does the Prognosis Change? An Analysis from the German States of Brandenburg and Berlin"],"prefix":"10.3390","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7463-9420","authenticated-orcid":false,"given":"Andreas","family":"Loew","sequence":"first","affiliation":[{"name":"Medical Clinic B, University Hospital Ruppin-Brandenburg (UKRB), Brandenburg Medical School, 16816 Neuruppin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"von Ruesten","sequence":"additional","affiliation":[{"name":"Clinical-Epidemiological Cancer Registry Brandenburg-Berlin (KKRBB), 03044 Cottbus, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constanze","family":"Schneider","sequence":"additional","affiliation":[{"name":"Clinical-Epidemiological Cancer Registry Brandenburg-Berlin (KKRBB), 03044 Cottbus, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Mantke","sequence":"additional","affiliation":[{"name":"Department of General and Visceral Surgery, Brandenburg University Hospital, Brandenburg Medical School, 14770 Brandenburg an der Havel, Germany"},{"name":"Faculty of Health Science Brandenburg, Joint Faculty of the Brandenburg University of Technology Cottbus-Senftenberg, the Brandenburg Medical School Theodor Fontane and the University of Potsdam, 14469 Potsdam, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5361-4327","authenticated-orcid":false,"given":"Karsten H.","family":"Weylandt","sequence":"additional","affiliation":[{"name":"Medical Clinic B, University Hospital Ruppin-Brandenburg (UKRB), Brandenburg Medical School, 16816 Neuruppin, Germany"},{"name":"Faculty of Health Science Brandenburg, Joint Faculty of the Brandenburg University of Technology Cottbus-Senftenberg, the Brandenburg Medical School Theodor Fontane and the University of Potsdam, 14469 Potsdam, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8151-4932","authenticated-orcid":false,"given":"Stephan","family":"Gretschel","sequence":"additional","affiliation":[{"name":"Faculty of Health Science Brandenburg, Joint Faculty of the Brandenburg University of Technology Cottbus-Senftenberg, the Brandenburg Medical School Theodor Fontane and the University of Potsdam, 14469 Potsdam, Germany"},{"name":"Department of General, Visceral, Thoracic and Vascular Surgery, University Hospital Ruppin-Brandenburg (UKRB), Brandenburg Medical School, 16816 Neuruppin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3322\/caac.21834","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. 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Cancer"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1053\/j.gastro.2020.05.006","article-title":"County Rurality and Socioeconomic Deprivation Is Associated With Reduced Survival From Gastric Cancer in the United States","volume":"159","author":"Huang","year":"2020","journal-title":"Gastroenterology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1016\/S1470-2045(16)30531-9","article-title":"Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): Results from the phase 2 part of a multicentre, open-label, randomised phase 2\/3 trial","volume":"17","author":"Hofheinz","year":"2016","journal-title":"Lancet Oncol."}],"container-title":["Current Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1718-7729\/32\/4\/228\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:14:31Z","timestamp":1760030071000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1718-7729\/32\/4\/228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,14]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["curroncol32040228"],"URL":"https:\/\/doi.org\/10.3390\/curroncol32040228","relation":{},"ISSN":["1718-7729"],"issn-type":[{"value":"1718-7729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,14]]}}}