{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:41:37Z","timestamp":1760060497029,"version":"build-2065373602"},"reference-count":31,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T00:00:00Z","timestamp":1757030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"U.S. National Cancer Institute","award":["5T32CA092203"],"award-info":[{"award-number":["5T32CA092203"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Purpose: To evaluate the prevalence and cancer-specific patterns of kidney stones among U.S. cancer survivors compared to non-cancer adults. Methods: This was a serial cross-sectional, descriptive epidemiologic analysis of a US nationally representative sample from the National Health and Nutrition Examination Survey from 2007 to 2020. Weighted prevalence of kidney stones was estimated for both non-cancer adults and cancer survivors by study cycle. Multivariable logistic regression was conducted to examine factors associated with higher probability of kidney stones in both non-cancer adults and cancer survivors. Results: From 2007\u20132008 to 2017\u20132020, kidney stone prevalence rose in both non-cancer adults (8.5% to 9.2%, p for trend = 0.013) and cancer survivors (13.1% to 17.3%, p for trend = 0.033). Throughout the study period, prevalence was consistently higher in cancer survivors. The overall prevalence from 2007 to 2020 was 15.8% (95% CI: 14.0\u201317.5%) in cancer survivors and 9.2% (95% CI: 8.8\u20139.6%) in non-cancer adults. After adjusting for sociodemographic, lifestyle, and health factors, cancer survivors had higher odds of kidney stones (OR = 1.28, 95% CI: 1.10\u20131.49). Compared with non-cancer adults, survivors of ovarian (OR = 3.71, 95% CI: 1.77\u20137.78), kidney (OR = 2.88, 95% CI: 1.46\u20135.68), bone and soft tissue (OR = 2.86, 95% CI: 1.12\u20137.30), uterine (OR = 1.94, 95% CI: 1.17\u20133.22), cervix (OR = 1.68, 95% CI: 1.08\u20132.61) and prostate (OR = 1.41, 95% CI: 1.06\u20131.87) cancers were statistically more likely to report kidney stones. The prevalence was numerically highest among survivors of kidney cancer (34.7%), followed by bone and soft tissue (29.9%), ovarian (29.8%), and testicular (26.3%) cancers. Conclusions: The higher prevalence of kidney stones in cancer survivors, with substantial variation by cancer type, highlights the urgent need for effective clinical management of kidney stones in oncology settings and mechanistic research.<\/jats:p>","DOI":"10.3390\/curroncol32090498","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T12:18:18Z","timestamp":1757074698000},"page":"498","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trend and Cancer-Specific Prevalence of Kidney Stones Among US Cancer Survivors, 2007\u20132020"],"prefix":"10.3390","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0455-1171","authenticated-orcid":false,"given":"Chao","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1670-606X","authenticated-orcid":false,"given":"Ruixuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA"},{"name":"Department of Health Service Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32611, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangren","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Health Service Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, FL 32611, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6603-6319","authenticated-orcid":false,"given":"Mohammad","family":"Abufaraj","sequence":"additional","affiliation":[{"name":"Department of Urology, Medical University of Vienna, 1009 Vienna, Austria"},{"name":"Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman 11942, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2043-8299","authenticated-orcid":false,"given":"Thomas","family":"Waldhoer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Center for Public Health, Medical University of Vienna, 1009 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey T.","family":"Gotto","sequence":"additional","affiliation":[{"name":"Southern Alberta Institute of Urology, Department of Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6627-6179","authenticated-orcid":false,"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology, Medical University of Vienna, 1009 Vienna, Austria"},{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA"},{"name":"Department of Urology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, NY 10032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1698-6666","authenticated-orcid":false,"given":"Lin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology and Prevention Research, Cancer Care Alberta, Calgary, AB T2N 5G2, Canada"},{"name":"Departments of Oncology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1093\/jnci\/djae135","article-title":"Prevalence of cancer survivors in the United States","volume":"116","author":"Tonorezos","year":"2024","journal-title":"JNCI J. 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