{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:20:22Z","timestamp":1792797622619,"version":"4.5.0"},"reference-count":53,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:00Z","timestamp":1760745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Background: The clinical characteristics of sarcopenia, including low muscular strength, are commonly seen among people with multiple myeloma. A scoping review was conducted to explore the role of exercise as a potential countermeasure for sarcopenia in this population. Our objectives were to (1) describe the design and findings of the studies and (2) identify the outcomes used in exercise-related studies to characterize sarcopenia. Methods: A systematic search (to March 2025) was conducted for published studies involving exercise or physical activity for individuals with multiple myeloma using key databases (MEDLINE, Embase, CINAHL, Scopus). Results: Of 971 articles reviewed, 12 articles were included, involving 967 total participants and 624 with multiple myeloma. All 12 studies included a measure for muscle physical performance, 9 studies included measures for muscular strength, and 7 studies included measures for muscle quantity\/quality. Five studies reported a significant improvement from exercise for measures of muscular strength, four studies reported a significant benefit for physical performance, and three studies reported a benefit in muscle quantity. Few studies included outcomes that met all the international criteria recommended to characterize sarcopenia. Conclusions: Further multicentre research trials are needed to better understand whether and how exercise may be helpful for people with multiple myeloma, especially in the context of sarcopenia.<\/jats:p>","DOI":"10.3390\/curroncol32100581","type":"journal-article","created":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:27:29Z","timestamp":1760963249000},"page":"581","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exercise Interventions to Address Sarcopenia in People with Multiple Myeloma: A Scoping Review"],"prefix":"10.3390","volume":"32","author":[{"given":"Leslie P.","family":"Ternes","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme M.","family":"Purdy","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1454-8555","authenticated-orcid":false,"given":"St\u00e9phanie","family":"Bernard","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada"},{"name":"\u00c9cole des Sciences de la R\u00e9adaptation, Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4376-4847","authenticated-orcid":false,"given":"Margaret L.","family":"McNeely","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada"},{"name":"Supportive Care and Patient Experience, Cancer Care Alberta, Edmonton, AB T6G 1Z2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1038\/bjc.2011.450","article-title":"Incidence of haematological malignancy by sub-type: A report from the Haematological Malignancy Research Network","volume":"105","author":"Smith","year":"2011","journal-title":"Br. 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