{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T12:38:27Z","timestamp":1763123907135,"version":"3.45.0"},"reference-count":43,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Oral and Maxillofacial Surgery, Regional High Specialty Hospital \u201cDr. Ignacio Morones Prieto\u201d"},{"name":"Department of Oral Surgery, Faculty of Dentistry, Autonomous University of San Luis Potosi"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Breast cancer rarely metastasizes to the parotid gland. Early recognition in patients with a history of malignancy is critical for timely diagnosis and treatment. We report the case of a 60-year-old female who presented with a two-month history of a left periauricular mass, 18 months after completing treatment for breast carcinoma. Despite the patient\u2019s oncologic history, initial evaluation by our maxillofacial surgery service showed no evidence of distant metastasis, and we initially ruled out metastatic disease. Clinical evaluation, contrast-enhanced computed tomography (CT), fine-needle aspiration cytology (FNAC), PET-CT, and histopathological analysis were performed. Given the persistent and progressive nature of the mass, surgical excision was undertaken to obtain a definitive diagnosis and provide local control. Immunohistochemical analysis of the resected mass and adjacent node confirmed metastatic breast carcinoma infiltrating the parotid parenchyma and an intra-parotid lymph node, with strong positivity for progesterone receptor (PR) and carcinoembryonic antigen (CEA). Unfortunately, several months later, the patient developed pulmonary metastases and subsequently died.<\/jats:p>","DOI":"10.3390\/curroncol32110634","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T11:49:43Z","timestamp":1763120983000},"page":"634","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Parotid Gland Mass as the First Manifestation of Recurrent Metastatic Breast Carcinoma: Diagnostic Pitfalls and Therapeutic Considerations in Oral-Maxillofacial Care"],"prefix":"10.3390","volume":"32","author":[{"given":"Esteban Ra\u00fal","family":"Mar-Uribe","sequence":"first","affiliation":[{"name":"Service of Oral and Maxillofacial Surgery, Regional High Specialty Hospital Dr. \u201cIgnacio Morones Prieto\u201d, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Angel","family":"Noyola-Fr\u00edas","sequence":"additional","affiliation":[{"name":"Service of Oral and Maxillofacial Surgery, Regional High Specialty Hospital Dr. \u201cIgnacio Morones Prieto\u201d, San Luis Potos\u00ed 78290, Mexico"},{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar Arturo","family":"Ben\u00edtez-C\u00e1rdenas","sequence":"additional","affiliation":[{"name":"Service of Oral and Maxillofacial Surgery, Regional High Specialty Hospital Dr. \u201cIgnacio Morones Prieto\u201d, San Luis Potos\u00ed 78290, Mexico"},{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elhi Manuel","family":"Torres-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Service of Oral and Maxillofacial Surgery, Regional High Specialty Hospital Dr. \u201cIgnacio Morones Prieto\u201d, San Luis Potos\u00ed 78290, Mexico"},{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adalberto","family":"Mosqueda-Taylor","sequence":"additional","affiliation":[{"name":"Department of Health Attention, Metropolitan Autonomous University Xochimilco, Mexico City 04960, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"S\u00e1nchez-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6032-3982","authenticated-orcid":false,"given":"Sof\u00eda","family":"Bernal-Silva","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2368-1529","authenticated-orcid":false,"given":"Andreu","family":"Comas-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"},{"name":"School of Medicine, Universidad Cuauht\u00e9moc San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Aguilar-Zapata","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Mart\u00ednez-Rider","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1659-7476","authenticated-orcid":false,"given":"Marlen","family":"Vitales-Noyola","sequence":"additional","affiliation":[{"name":"Endodontics Postgraduate Program, Faculty of Dentistry, Autonomous University of San Luis Potos\u00ed, San Luis Potos\u00ed 78290, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"ref_1","first-page":"6","article-title":"Breast cancer","volume":"1","author":"Franc","year":"2024","journal-title":"Breast Cancer"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/s41571-021-00514-z","article-title":"Planning for tomorrow: Global cancer incidence and the role of prevention 2020\u20132070","volume":"18","author":"Soerjomataram","year":"2021","journal-title":"Nat. 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