{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:38:55Z","timestamp":1785411535105,"version":"3.56.0"},"reference-count":40,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008730","name":"Norwegian Cancer Society","doi-asserted-by":"publisher","award":["201842"],"award-info":[{"award-number":["201842"]}],"id":[{"id":"10.13039\/100008730","id-type":"DOI","asserted-by":"publisher"}]},{"award":["201842"],"award-info":[{"award-number":["201842"]}],"id":[{"id":"https:\/\/ror.org\/01925vb10","id-type":"ROR","asserted-by":"publisher"}]},{"name":"ClinicalTrials.gov","award":["NCT04541056"],"award-info":[{"award-number":["NCT04541056"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Oncology"],"abstract":"<jats:p>Survivors of childhood acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin lymphoma (NHL) are at risk of developing long-term adverse effects after survival. This study examined observed proportions of perceived mental distress, fatigue, and executive function (EF) impairment in adult childhood cancer survivors (CCSs) of ALL, AML, and NHL. Secondly, it examined the association between perceived EF impairment and mental distress or fatigue. Participants (n = 132; 57% female) were recruited from two major Norwegian hospitals. Self-report questionnaires included the Behavior Rating Inventory of Executive Function, Adult Version, the Hopkins Symptom Checklist-25, and the Fatigue Severity Scale. Proportions exceeding established clinical thresholds were calculated, and groups were compared using Pearson\u2019s chi-squared test and Newcombe confidence intervals. Overall, 49% and 41% of participants met the clinical thresholds for depression and anxiety; 43% for fatigue; and 28% for EF impairment. Perceived EF impairment was significantly associated with mental distress and fatigue. Mental distress, fatigue, and EF impairment are commonly reported and distressing late effects among CCSs of ALL, AML, and NHL. Follow-up care focusing on neurocognitive and psychological outcomes is important for the long-term functioning and well-being of this survivor group. Targeted neurocognitive rehabilitation may represent a key component of follow-up care.<\/jats:p>","DOI":"10.3390\/curroncol33070397","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T12:41:38Z","timestamp":1782909698000},"page":"397","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mental Distress, Fatigue and Executive Function in Adult Survivors of Childhood Leukemia and Non-Hodgkin Lymphoma"],"prefix":"10.3390","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3110-5677","authenticated-orcid":false,"given":"Anna R.","family":"Franz\u00e9n","sequence":"first","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9592-8589","authenticated-orcid":false,"given":"Jan","family":"Stubberud","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Oslo, 0373 Oslo, Norway"},{"name":"Department of Research, Lovisenberg Diaconal Hospital, 0440 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5258-500X","authenticated-orcid":false,"given":"Torstein B.","family":"R\u00f8","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway"},{"name":"Children\u2019s Clinic, St. Olavs Hospital, Trondheim University Hospital, 7006 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6613-8596","authenticated-orcid":false,"given":"Stian","family":"Lydersen","sequence":"additional","affiliation":[{"name":"Regional Center for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, 7030 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6230-8957","authenticated-orcid":false,"given":"Kaja S.","family":"Egset","sequence":"additional","affiliation":[{"name":"Department of Psychology, Norwegian University of Science and Technology, 7491 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Ruud","sequence":"additional","affiliation":[{"name":"Division for Pediatric and Adolescent Medicine, Oslo University Hospital, 0424 Oslo, Norway"},{"name":"Institute of Clinical Medicine, University of Oslo, 0372 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9172-309X","authenticated-orcid":false,"given":"Siri","family":"Weider","sequence":"additional","affiliation":[{"name":"Department of Psychology, Norwegian University of Science and Technology, 7491 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8003-8946","authenticated-orcid":false,"given":"Mary-Elizabeth","family":"Eilertsen","sequence":"additional","affiliation":[{"name":"Department of Public Health and Nursing, Center for Health Promotion Research, Norwegian University of Science and Technology, 7491 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Mari","family":"Sund","sequence":"additional","affiliation":[{"name":"Regional Center for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, 7030 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trude","family":"Reinfjell","sequence":"additional","affiliation":[{"name":"Department of Psychology, Norwegian University of Science and Technology, 7491 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9455-3110","authenticated-orcid":false,"given":"Magnus A.","family":"Hjort","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway"},{"name":"Children\u2019s Clinic, St. Olavs Hospital, Trondheim University Hospital, 7006 Trondheim, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.neubiorev.2015.03.016","article-title":"Neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on contemporary treatment protocols: A systematic review","volume":"53","author":"Cheung","year":"2015","journal-title":"Neurosci. 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