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Oncol.","Current Oncology"],"abstract":"<jats:p>Background: Despite the observed association between death anxiety and experiential avoidance, their joint short-term trajectories in patients with newly diagnosed cancer remain unclear. This study aimed to identify joint trajectories of death anxiety and experiential avoidance during early cancer care. Methods: This secondary longitudinal analysis included 266 adults with newly diagnosed cancer recruited at Hunan Cancer Hospital, China, between April and September 2022. Death anxiety and experiential avoidance were assessed using the 15-item Templer Death Anxiety Scale (DAS) and the seven-item Acceptance and Action Questionnaire-II (AAQ-II), respectively, at hospital admission, discharge, and one month after discharge. This interval represented the acute adaptation phase after diagnosis and treatment initiation. Outcome-specific trajectory models informed a fully crossed dual-trajectory model. Results: Participants (mean age, 48.33 \u00b1 11.18 years; 53.8% male) followed three jointly re-estimated declining DAS trajectories (low, 37.3%; moderate, 26.5%; high, 36.3%) and two declining AAQ-II trajectories (low, 70.6%; high, 29.4%). In the dual-trajectory model (entropy = 0.849), the probability of high-AAQ-II increased across low, moderate, and high-DAS trajectories (8.5%, 18.7%, and 58.6%), and 72.3% of the high-AAQ-II trajectory followed the high-DAS trajectory. A high-DAS\/low-AAQ-II combination accounted for 15.0%, indicating incomplete correspondence. Conclusions: During early care after cancer diagnosis, high-AAQ-II membership was concentrated in higher DAS trajectories, whereas high-DAS could also accompany low-AAQ-II.<\/jats:p>","DOI":"10.3390\/curroncol33090546","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:02:48Z","timestamp":1788962568000},"page":"546","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Joint Trajectories of Death Anxiety and Experiential Avoidance After Cancer Diagnosis: A Longitudinal Study"],"prefix":"10.3390","volume":"33","author":[{"given":"Yiguo","family":"Deng","sequence":"first","affiliation":[{"name":"School of Nursing, Guangzhou Medical University, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"software","vocabulary":"credit"}]},{"given":"Furong","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Nursing, Guangzhou Medical University, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"given":"Siyu","family":"Li","sequence":"additional","affiliation":[{"name":"School of Nursing, Guangzhou Medical University, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Qihan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Nursing, Guangzhou Medical University, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5473-4320","authenticated-orcid":false,"given":"Jiaying","family":"Li","sequence":"additional","affiliation":[{"name":"The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4437-3947","authenticated-orcid":false,"given":"Zengjie","family":"Ye","sequence":"additional","affiliation":[{"name":"School of Nursing, Guangzhou Medical University, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"project-administration","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"ref_1","first-page":"47","article-title":"Cancer Incidence and Mortality in China, 2022","volume":"4","author":"Han","year":"2024","journal-title":"J. Natl. Cancer Cent."},{"key":"ref_2","first-page":"4623","article-title":"Systematic Review of Illness Uncertainty Management Interventions for Cancer Patients and Their Family Caregivers","volume":"29","author":"Guan","year":"2021","journal-title":"Support. Care Cancer"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1038\/s41416-021-01542-3","article-title":"The Mental Health Impacts of Receiving a Breast Cancer Diagnosis: A Meta-Analysis","volume":"125","author":"Fortin","year":"2021","journal-title":"Br. J. Cancer"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1093\/nop\/npaa015","article-title":"Death-Related Distress in Adult Primary Brain Tumor Patients","volume":"7","author":"Loughan","year":"2020","journal-title":"Neuro-Oncol. Pract."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1111\/jocn.17021","article-title":"Correlates of Death Anxiety for Patients with Cancer: A Systematic Review and Meta-Analysis","volume":"33","author":"Li","year":"2024","journal-title":"J. Clin. Nurs."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1037\/0022-006X.64.6.1152","article-title":"Experiential Avoidance and Behavioral Disorders: A Functional Dimensional Approach to Diagnosis and Treatment","volume":"64","author":"Hayes","year":"1996","journal-title":"J. Consult. Clin. Psychol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1002\/cncr.30025","article-title":"The Relationship between Coping Strategies, Quality of Life, and Mood in Patients with Incurable Cancer","volume":"122","author":"Nipp","year":"2016","journal-title":"Cancer"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s12529-022-10131-4","article-title":"Experiential Avoidance in Advanced Cancer: A Mixed-Methods Systematic Review","volume":"30","author":"Davis","year":"2023","journal-title":"Int. J. Behav. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"101973","DOI":"10.1016\/j.cpr.2021.101973","article-title":"Defining and Measuring Psychological Flexibility: A Narrative Scoping Review of Diverse Flexibility and Rigidity Constructs and Perspectives","volume":"84","author":"Cherry","year":"2021","journal-title":"Clin. Psychol. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.5152\/pcp.2024.23777","article-title":"Experiential Avoidance Process Model: A Review of the Mechanism for the Generation and Maintenance of Avoidance Behavior","volume":"34","author":"Wang","year":"2024","journal-title":"Psychiatry Clin. Psychopharmacol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1108\/EOR-02-2023-0003","article-title":"Accepting the Unacceptable? Exploring How Acceptance Relates to Quality of Life and Death Anxiety in a Cancer Population","volume":"1","author":"Brabbins","year":"2023","journal-title":"Emerald Open Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e064104","DOI":"10.1136\/bmjopen-2022-064104","article-title":"Factors Influencing Death Anxiety among Chinese Patients with Cancer: A Cross-Sectional Study","volume":"12","author":"Gong","year":"2022","journal-title":"BMJ Open"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1177\/0962280216673085","article-title":"Group-Based Multi-Trajectory Modeling","volume":"27","author":"Nagin","year":"2018","journal-title":"Stat. Methods Med. Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1037\/1082-989X.6.1.18","article-title":"Analyzing Developmental Trajectories of Distinct but Related Behaviors: A Group-Based Method","volume":"6","author":"Nagin","year":"2001","journal-title":"Psychol. Methods"},{"key":"ref_15","first-page":"1052","article-title":"A Longitudinal Study of Death Anxiety in Patients with Newly Diagnosed Cancer","volume":"37","author":"Chen","year":"2023","journal-title":"Chin. Ment. Health J."},{"key":"ref_16","first-page":"53","article-title":"Study on the Cross-Cultural Adjustment and Application of the Death Anxiety Scale","volume":"28","author":"Yang","year":"2012","journal-title":"Chin. J. Pract. Nurs."},{"key":"ref_17","first-page":"873","article-title":"Reliability and Validity of the Chinese Version of the Acceptance and Action Questionnaire-Second Edition (AAQ-II) in College Students","volume":"27","author":"Cao","year":"2013","journal-title":"Chin. Ment. Health J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1089\/jpm.2020.0543","article-title":"Using Admission Karnofsky Performance Status as a Guide for Palliative Care Discharge Needs","volume":"24","author":"Mehta","year":"2021","journal-title":"J. Palliat. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1037\/1082-989X.4.2.139","article-title":"Analyzing Developmental Trajectories: A Semiparametric, Group-Based Approach","volume":"4","author":"Nagin","year":"1999","journal-title":"Psychol. Methods"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.clinpsy.121208.131413","article-title":"Group-Based Trajectory Modeling in Clinical Research","volume":"6","author":"Nagin","year":"2010","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"ref_21","unstructured":"Muth\u00e9n, L.K., and Muth\u00e9n, B.O. (2017). Mplus User\u2019s Guide, Muth\u00e9n & Muth\u00e9n. [8th ed.]. Available online: https:\/\/www.statmodel.com\/HTML_UG\/indexV8.shtml."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/biomet\/88.3.767","article-title":"Testing the Number of Components in a Normal Mixture","volume":"88","author":"Lo","year":"2001","journal-title":"Biometrika"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1080\/10705510701575396","article-title":"Deciding on the Number of Classes in Latent Class Analysis and Growth Mixture Modeling: A Monte Carlo Simulation Study","volume":"14","author":"Nylund","year":"2007","journal-title":"Struct. Equ. Model."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1080\/10705511.2014.915181","article-title":"Auxiliary Variables in Mixture Modeling: Three-Step Approaches Using Mplus","volume":"21","author":"Asparouhov","year":"2014","journal-title":"Struct. Equ. Model."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1177\/0898264320953693","article-title":"Dual Trajectories of Social Isolation and Dementia in Older Adults: A Population-Based Longitudinal Study","volume":"33","author":"Xiang","year":"2021","journal-title":"J. Aging Health"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Lv, Q., Chang, H., Wang, Y., Xu, X., Liu, J., He, Y., Fu, L., Lin, M., Gao, X., and Zang, X. (2025). Co-Occurring Self-Efficacy, Anxiety, and Depression in Caregivers of Patients with Heart Failure: A Group-Based Dual-Trajectory Modeling Approach. BMC Nurs., 24.","DOI":"10.1186\/s12912-025-02995-0"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1177\/0049124106292364","article-title":"Advances in Group-Based Trajectory Modeling and an SAS Procedure for Estimating Them","volume":"35","author":"Jones","year":"2007","journal-title":"Sociol. Methods Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10549-022-06805-y","article-title":"A Detailed Description of the Distress Trajectory from Pre- to Post-Treatment in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy","volume":"197","author":"Lacourt","year":"2023","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_29","first-page":"4255","article-title":"Psychosocial Distress Is Dynamic across the Spectrum of Cancer Care and Requires Longitudinal Screening for Patient-Centered Care","volume":"30","author":"Sutton","year":"2022","journal-title":"Support. Care Cancer"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Yan, Y., Chen, Y., Ou, M., Gong, Y., Yang, R., Liu, X., Xia, W., Chen, F., Zheng, H., and Xu, X. (2024). The Mediating Role of Meaning in Life between Experiential Avoidance and Death Anxiety among Cancer Patients: A Cross-Sectional Study. BMC Cancer, 24.","DOI":"10.1186\/s12885-024-12433-0"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Jimenez, A., Rochefort Mod\u00e9n, C., and Chmielewski, M. (2026). Assessing Experiential Avoidance: Further Testing of the AAQ-II and the MEAQ. Assessment, 10731911261423143.","DOI":"10.1177\/10731911261423143"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"450","DOI":"10.6004\/jnccn.2023.0026","article-title":"NCCN Guidelines\u00ae Insights: Distress Management, Version 2.2023","volume":"21","author":"Riba","year":"2023","journal-title":"J. Natl. Compr. Cancer Netw."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1200\/JCO.23.00293","article-title":"Management of Anxiety and Depression in Adult Survivors of Cancer: ASCO Guideline Update","volume":"41","author":"Andersen","year":"2023","journal-title":"J. Clin. Oncol."}],"container-title":["Current Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1718-7729\/33\/9\/546\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T04:14:12Z","timestamp":1789100052000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1718-7729\/33\/9\/546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,9]]},"references-count":33,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["curroncol33090546"],"URL":"https:\/\/doi.org\/10.3390\/curroncol33090546","relation":{},"ISSN":["1718-7729"],"issn-type":[{"value":"1718-7729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,9]]}}}