{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T09:11:38Z","timestamp":1789031498343,"version":"build-2803163510"},"reference-count":36,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr. Oncol.","Current Oncology"],"abstract":"<jats:p>This is a consensus-based Canadian review with the primary purpose of expanding knowledge regarding supportive and topical therapies for chronic graft vs. host disease (cGvHD). There is often a lack of confidence in treating certain organ specific manifestations, and access to specialists with organ specific expertise varies across the country. This paper covers information gained from a literature review and Canadian transplanter expertise and will serve as a guide for hematopoietic cell transplant healthcare providers to topical cGvHD therapies accessible in Canada. We will review common symptoms and signs focused specifically on skin, mouth, eye and genital tract cGvHD and on lifestyle modifications and topical treatments as an adjunct to our recent publication on systemic treatment for cGvHD.<\/jats:p>","DOI":"10.3390\/curroncol33090548","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T08:07:41Z","timestamp":1789027661000},"page":"548","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease"],"prefix":"10.3390","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7287-0924","authenticated-orcid":false,"given":"Kylie","family":"Lepic","sequence":"first","affiliation":[{"name":"Juravinski Cancer Centre, McMaster University, Hamilton, ON L8V 5C2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6299-493X","authenticated-orcid":false,"given":"Joseph","family":"Aziz","sequence":"additional","affiliation":[{"name":"Juravinski Cancer Centre, McMaster University, Hamilton, ON L8V 5C2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gizelle","family":"Popradi","sequence":"additional","affiliation":[{"name":"McGill University Health Centre, Montreal, QC H4P 2P5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0281-5866","authenticated-orcid":false,"given":"Christopher","family":"Lemieux","sequence":"additional","affiliation":[{"name":"CHU de Qu\u00e9bec, Universit\u00e9 Laval, Qu\u00e9bec, QC G1R 2J6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"White","sequence":"additional","affiliation":[{"name":"Vancouver General Hospital, British Columbia Cancer Agency, University of British Columbia, Vancouver, BC V5Z 1M9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Maier","sequence":"additional","affiliation":[{"name":"Cell Therapy Transplant Canada, Winnipeg, MB R3P 2R8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7622-4065","authenticated-orcid":false,"given":"Mohamed","family":"Elemary","sequence":"additional","affiliation":[{"name":"Saskatchewan Cancer Agency, University of Saskatchewan, Saskatchewan, SK S7N 4H4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk","family":"Schultz","sequence":"additional","affiliation":[{"name":"British Columbia Children\u2019s Hospital, University of British Columbia, Vancouver, BC V6H 3N1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristjan","family":"Paulson","sequence":"additional","affiliation":[{"name":"Cancer Care Manitoba, University of Manitoba, Winnipeg, MB R3E 0V9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram","family":"Vasudevan Nampoothiri","sequence":"additional","affiliation":[{"name":"Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3261-8289","authenticated-orcid":false,"given":"David","family":"Allan","sequence":"additional","affiliation":[{"name":"Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis Dong Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2M9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1182\/hematology.2021000301","article-title":"Updates in chronic graft-versus-host disease","volume":"2021","author":"Hamilton","year":"2021","journal-title":"Hematol. 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