{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T05:58:44Z","timestamp":1781848724347,"version":"3.54.5"},"reference-count":42,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,4,25]],"date-time":"2020-04-25T00:00:00Z","timestamp":1587772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud\u2019s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The aim of this study is to describe the diagnostic role of NVC in a series of 361 consecutive patients with interstitial lung disease (ILD). All the patients were assessed by clinical pulmonary and rheumatic examinations, blood exams, high-resolution computed tomography and NVC. NVC was considered positive only in the presence of avascular areas or giant capillaries, but also, the presence of bushy capillaries (BCs) was recorded. NVC was positive in 17.7% of ILD patients and in 78.1% of ILD patients associated with a diagnosis of connective tissue disease (CTD). In 25% of SSc-ILD patients, NVC proved necessary for a correct diagnosis. The presence of BCs and\/or NVC positivity in ILD patients with normal levels of creatine phosphokinase is associated with amyopathic IIM, regardless the presence of RP. In conclusion, NVC is useful for the diagnostic assessment of incomplete forms of CTD and in amyopathic IIMs. NVC should be considered in the diagnostic assessment of ILD patients regardless of the presence of RP.<\/jats:p>","DOI":"10.3390\/diagnostics10050253","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T04:15:29Z","timestamp":1587960929000},"page":"253","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients"],"prefix":"10.3390","volume":"10","author":[{"given":"Domenico","family":"Sambataro","sequence":"first","affiliation":[{"name":"Artroreuma S.R.L., Outpatient of Rheumatology associated with the National Health System corso S. Vito 53, 95030 Mascalucia, Italy"},{"name":"Department of Clinical and Experimental Medicine, Internal Medicine Unit, Cannizzaro Hospital, University of Catania, via Messina 829, 95100 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9933-1202","authenticated-orcid":false,"given":"Gianluca","family":"Sambataro","sequence":"additional","affiliation":[{"name":"Artroreuma S.R.L., Outpatient of Rheumatology associated with the National Health System corso S. Vito 53, 95030 Mascalucia, Italy"},{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Libra","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Vignigni","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pino","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelina","family":"Fagone","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Fruciano","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Gili","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pignataro","sequence":"additional","affiliation":[{"name":"Scleroderma Clinic, Department of Rheumatology, ASST G. Pini-CTO, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoletta","family":"Del Papa","sequence":"additional","affiliation":[{"name":"Scleroderma Clinic, Department of Rheumatology, ASST G. Pini-CTO, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Vancheri","sequence":"additional","affiliation":[{"name":"Regional Referral Centre for Rare Lung Diseases, A. O. U. \u201cPoliclinico-Vittorio Emanuele\u201d Dept. of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1183\/09059180.00009113","article-title":"Interstitial Lung Disease","volume":"23","author":"Antoniou","year":"2014","journal-title":"Eur. Respir. 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