{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T21:50:55Z","timestamp":1784325055958,"version":"3.55.0"},"reference-count":43,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T00:00:00Z","timestamp":1608854400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2018-R1D1A1A02085328"],"award-info":[{"award-number":["NRF-2018-R1D1A1A02085328"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2020-R1G1A1005390"],"award-info":[{"award-number":["NRF-2020-R1G1A1005390"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>This study aims to assess the relationship between chronic rhinosinusitis (CRS) and dyslipidemia in a Korean population. The population aged 40 years or over was selected from the Korean National Health Insurance Service-National Health Screening Cohort. CRS was defined if patients were treated \u22652 times with ICD-10 code (J32) and underwent head and neck computed tomography. Patients with CRS were classified as having nasal polyps (J33) or not. Dyslipidemia was defined if participants with the ICD-10 code (E78) were treated \u22652 times from 2002 to 2015. A total of 6163 patients with CRS were matched with 24,652 controls (1:4 ratio) for sex, age, income, and residence. The adjusted odds ratios (aORs) of a previous dyslipidemia in patients with CRS were analyzed by conditional logistic regression analysis, adjusted for confounding factors. The prevalence of dyslipidemia was significantly higher in participants with CRS (26.1%) than in the controls (20.6%) (p &lt; 0.001). There was a significant positive association between CRS with\/without nasal polyps and dyslipidemia (aOR = 1.36, 95%CI = 1.26\u20131.47, p &lt; 0.001). The association between CRS and dyslipidemia was stronger for CRS without nasal polyps (aOR = 1.42, 95% CI = 1.28\u20131.57, p &lt; 0.001) than for CRS with nasal polyps (aOR = 1.31, 95% CI = 1.17\u20131.47, p &lt; 0.001). All age and sex subgroups exhibited consistent results. A personal history of dyslipidemia was associated with risk of CRS regardless of total cholesterol and the use of statins.<\/jats:p>","DOI":"10.3390\/diagnostics11010026","type":"journal-article","created":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T09:30:19Z","timestamp":1608888619000},"page":"26","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6513-7011","authenticated-orcid":false,"given":"Jee Hye","family":"Wee","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0629-9299","authenticated-orcid":false,"given":"Chanyang","family":"Min","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory, College of Medicine, Hallym University, Anyang 14068, Korea"},{"name":"Graduate School of Public Health, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Woo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, Kangdong Sacred Heart Hospital, Seoul 05355, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0739-7971","authenticated-orcid":false,"given":"Soo Hwan","family":"Byun","sequence":"additional","affiliation":[{"name":"Department of Oral &amp; Maxillofacial Surgery, Dentistry, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Jeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5267-0135","authenticated-orcid":false,"given":"Chang Myeon","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, College of Medicine, Hanyang University, Seoul 04763, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bumjung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-9549","authenticated-orcid":false,"given":"Hyo Geun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head &amp; Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, Korea"},{"name":"Hallym Data Science Laboratory, College of Medicine, Hallym University, Anyang 14068, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.rmed.2018.06.016","article-title":"Pediatric rhinosinusitis and asthma","volume":"141","author":"Poddighe","year":"2018","journal-title":"Respir. 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