{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:52:56Z","timestamp":1760233976670,"version":"build-2065373602"},"reference-count":9,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T00:00:00Z","timestamp":1614643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>The spreading pattern of ovarian carcinoma is unique and unlike most other cancers, because exfoliated ovarian cancer cells primarily disseminate within the abdominal cavity, which are then transported throughout the peritoneum by physiological peritoneal fluid. An initial manifestation of a solitary peridiaphragmatic distant metastatic lymph node without peritoneal involvement is very rare. This study reports a case with an incidentally found single hypermetabolic mass in the peridiaphragmatic space without a pelvic lesion in the baseline staging 18 F-FDG PET\/CT that histologically turned out to be metastatic serous papillary carcinoma due to ovarian cancer. 18F-FDG PET\/CT may allow the identification of the initial manifestation of unexpected distant oligometastatic statuses of an unknown primary ovarian cancer.<\/jats:p>","DOI":"10.3390\/diagnostics11030422","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T21:24:01Z","timestamp":1614720241000},"page":"422","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidental Detection of Ovarian Cancer as a Solitary Peridiaphragmatic Distant Lymph Node Metastasis without Pelvic Lesions on 18F-FDG PET\/CT"],"prefix":"10.3390","volume":"11","author":[{"given":"Hye Joo","family":"Son","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Dankook University College of Medicine, 201 Manghyang-ro, Dongnam-gu, Cheonan, Chung Nam 31116, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4302-9263","authenticated-orcid":false,"given":"Yong-Moon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dankook University College of Medicine, 201 Manghyang-ro, Dongnam-gu, Cheonan, Chung Nam 31116, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jai-Hyuen","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Dankook University College of Medicine, 201 Manghyang-ro, Dongnam-gu, Cheonan, Chung Nam 31116, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1056\/NEJM198310133091503","article-title":"A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer","volume":"309","author":"Bast","year":"1983","journal-title":"N. Engl. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"735","DOI":"10.3892\/ol.2013.1121","article-title":"PAX8 is a novel marker for differentiating between various types of tumor, particularly ovarian epithelial carcinomas","volume":"5","author":"Xiang","year":"2013","journal-title":"Oncol. Lett."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/S0009-9260(99)91178-9","article-title":"Supradiaphragmatic manifestations of papillary serous adenocarcinoma of the ovary","volume":"54","author":"Patel","year":"1999","journal-title":"Clin. Radiol."},{"doi-asserted-by":"crossref","unstructured":"Thomakos, N., Diakosavvas, M., Machairiotis, N., Fasoulakis, Z., Zarogoulidis, P., and Rodolakis, A. (2019). Rare Distant Metastatic Disease of Ovarian and Peritoneal Carcinomatosis: A Review of the Literature. Cancers, 11.","key":"ref_4","DOI":"10.3390\/cancers11081044"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"783","DOI":"10.3349\/ymj.2002.43.6.783","article-title":"Lymph node metastasis in a gynecologic malignancy","volume":"43","author":"Kamura","year":"2002","journal-title":"Yonsei Med. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1245\/s10434-009-0486-5","article-title":"Pathological diagnosis and cytoreduction of cardiophrenic lymph node and pleural metastasis in ovarian cancer patients using video-assisted thoracic surgery","volume":"16","author":"Lim","year":"2009","journal-title":"Ann. Surg. Oncol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/S0140-6736(13)62146-7","article-title":"Ovarian cancer","volume":"384","author":"Jayson","year":"2014","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.2353\/ajpath.2010.100105","article-title":"Ovarian cancer development and metastasis","volume":"177","author":"Lengyel","year":"2010","journal-title":"Am. J. Pathol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/LBR.0000000000000283","article-title":"Calcified Mediastinal Metastasis of Ovarian Cancer Mimicking Broncholithiasis","volume":"23","author":"Dhillon","year":"2016","journal-title":"J. Bronchol. Interv. Pulmonol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/3\/422\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:31:40Z","timestamp":1760160700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/3\/422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,2]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3]]}},"alternative-id":["diagnostics11030422"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics11030422","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2021,3,2]]}}}