{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T03:05:05Z","timestamp":1769915105978,"version":"3.49.0"},"reference-count":20,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors of the gastrointestinal tract (GIT), usually occur as a solitary neoplasm. Inflammatory florid polyp (IFP) is a solitary rare benign lesion of the gastrointestinal tract, mainly occur in the gastric antrum, whose atypical presentation can mimic GISTs or other malignant tumors, therefore the synchronous occurrence of GISTs and IFP is extremely rare. We had a case of a 58-year-old man that was presented with recurrent epigastric pain and recurrent melena. Upper endoscopic examination revealed a large polypoid antrum polyp measured 7 cm at greatest dimension with focal ulceration. Clinical and radiological features did not reach the definite diagnosis until histopathological evaluation with immunohistochemical analysis was performed. Surgical intervention is recommended and partial gastrectomy was done with wide resection margins. Histological examination revealed two distinct GISTs and IFP parts presenting a collision tumor that showed spindle and epitheloid cells consistent with GISTs with histological features of florid polyp showed a characteristic perivascular onion-skin arrangement of spindle cells with dense chronic inflammatory infiltrate including eosinophils and lymphocytes. Immunohistochemical studies have been done and revealed an association between GISTs and IFP. To the best of our knowledge, this is the first case of a collision tumor consisting of a GIST and an IFP arising in the stomach. In conclusion, the gastrointestinal stromal tumor is the comments mesenchymal tumor of GIT and IFP is a rare benign lesion of GIT therefore association between GIST and IFP as a collision tumor is extremely rare.<\/jats:p>","DOI":"10.3390\/diagnostics11040633","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T07:23:17Z","timestamp":1617261797000},"page":"633","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preoperative Diagnosis Failure for a Rare Gastric Collision Tumor: A Case Report"],"prefix":"10.3390","volume":"11","author":[{"given":"Rabie E.","family":"Elshaer","sequence":"first","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eid R.","family":"Elgammal","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr M.","family":"Elmistekawy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walaa A.","family":"Ghannam","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Suez University, Suez 43533, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed E.","family":"Elshamy","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Al-Azhar University, New Damietta 71524, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4937-1182","authenticated-orcid":false,"given":"Sally Y.","family":"Abed","sequence":"additional","affiliation":[{"name":"Department of Respiratory Care, College of Applied Medical Science in Jubail, Imam Abdulrahman Bin Faisal University, Jubail 35816, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9688-7683","authenticated-orcid":false,"given":"Sawsan A.","family":"Zaitone","sequence":"additional","affiliation":[{"name":"Department of Pharmacology &amp; Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt"},{"name":"Department of Pharmacology &amp; Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk 47512, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/314158","article-title":"Gastric Collision Tumors: An Insight into Their Origin and Clinical Significance","volume":"2015","author":"Michalinos","year":"2015","journal-title":"Gastroenterol. 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