{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:55:00Z","timestamp":1787169300637,"version":"build-2736575974"},"reference-count":44,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N0137941\/1"],"award-info":[{"award-number":["MR\/N0137941\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Speckle tracking echocardiography (STE) has gained importance in the evaluation of adult inherited cardiomyopathies, but its utility in children is not well characterized. We conducted a systematic review to evaluate the role of STE in pediatric inherited cardiomyopathies. PubMed, EMBASE, Web of Science, Scopus, CENTRAL and CINAHL databases were searched up to May 2020, for terms related to inherited cardiomyopathies and STE. Included were dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), left ventricular non-compaction (LVNC) and arrhythmogenic cardiomyopathy (ACM). A total of 14 cohorts were identified, of which six were in DCM, four in HCM, three in LVNC and one in ACM. The most commonly reported STE measurements were left ventricular longitudinal strain (Sl), circumferential strain (Sc), radial strain (Sr) and rotation\/torsion\/twist. Sl, Sc and were abnormal in all DCM and LVNC cohorts, but not in all HCM. Apical rotation and twist\/torsion were increased in HCM, and decreased in LVNC. Abnormal STE parameters were reported even in cohorts with normal non-STE systolic\/diastolic measurements. STE in childhood cardiomyopathies can detect early changes which may not be associated with changes in cardiac function detectable by non-STE methods. Longitudinal and circumferential strain should be introduced in the cardiomyopathy echocardiography protocol, reflecting current practice in adults.<\/jats:p>","DOI":"10.3390\/diagnostics11040635","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T07:23:17Z","timestamp":1617261797000},"page":"635","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The Role of Speckle Tracking Echocardiography in the Evaluation of Common Inherited Cardiomyopathies in Children and Adolescents: A Systematic Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2443-1019","authenticated-orcid":false,"given":"Dan M.","family":"Dorobantu","sequence":"first","affiliation":[{"name":"Children\u2019s Health and Exercise Research Centre (CHERC), University of Exeter, Exeter EX1 1TX, UK"},{"name":"Population Health Sciences Department, University of Bristol, Bristol BS8 2PS, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3275-7975","authenticated-orcid":false,"given":"Curtis A.","family":"Wadey","sequence":"additional","affiliation":[{"name":"Children\u2019s Health and Exercise Research Centre (CHERC), University of Exeter, Exeter EX1 1TX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurul H.","family":"Amir","sequence":"additional","affiliation":[{"name":"Population Health Sciences Department, University of Bristol, Bristol BS8 2PS, UK"},{"name":"Faculty of Sport Science and Recreation, Universiti Teknologi MARA, Perlis Branch, Arau Campus, Perlis 40450, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2789-2216","authenticated-orcid":false,"given":"A. Graham","family":"Stuart","sequence":"additional","affiliation":[{"name":"Population Health Sciences Department, University of Bristol, Bristol BS8 2PS, UK"},{"name":"National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Centre, Congenital Heart Unit, Bristol Heart Institute, Bristol BS2 8ED, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1740-6248","authenticated-orcid":false,"given":"Craig A.","family":"Williams","sequence":"additional","affiliation":[{"name":"Children\u2019s Health and Exercise Research Centre (CHERC), University of Exeter, Exeter EX1 1TX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido E.","family":"Pieles","sequence":"additional","affiliation":[{"name":"Population Health Sciences Department, University of Bristol, Bristol BS8 2PS, UK"},{"name":"National Institute for Health Research (NIHR) Cardiovascular Biomedical Research Centre, Congenital Heart Unit, Bristol Heart Institute, Bristol BS2 8ED, UK"},{"name":"Institute of Sport, Exercise and Health, University College London, London W1T 7HA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.hfc.2010.05.002","article-title":"The Pediatric Cardiomyopathy Registry and Heart Failure: Key Results from the First 15 Years","volume":"6","author":"Wilkinson","year":"2010","journal-title":"Heart Fail. 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