{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:04:08Z","timestamp":1760234648639,"version":"build-2065373602"},"reference-count":77,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T00:00:00Z","timestamp":1621987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Right ventricular (RV) systolic function represents an important independent predictor of adverse outcomes in many cardiovascular (CV) diseases. However, conventional parameters of RV systolic function (tricuspid annular plane excursion (TAPSE), RV myocardial performance index (MPI), and fractional area change (FAC)) are not always able to detect subtle changes in RV function. New evidence indicates a significantly higher predictive value of RV longitudinal strain (LS) over conventional parameters. RVLS showed higher sensitivity and specificity in the detection of RV dysfunction in the absence of RV dilatation, apparent wall motion abnormalities, and reduced global RV systolic function. Additionally, RVLS represents a significant and independent predictor of adverse outcomes in patients with dilated cardiomyopathy (CMP), hypertrophic CMP, arrhythmogenic RV CMP, and amyloidosis, but also in patients with connective tissue diseases and patients with coronary artery disease. Due to its availability, echocardiography remains the main imaging tool for RVLS assessment, but cardiac magnetic resonance (CMR) also represents an important additional imaging tool in RVLG assessment. The findings from the large studies support the routine evaluation of RVLS in the majority of CV patients, but this has still not been adopted in daily clinical practice. This clinical review aims to summarize the significance and predictive value of RVLS in patients with different types of cardiomyopathies, tissue connective diseases, and coronary artery disease.<\/jats:p>","DOI":"10.3390\/diagnostics11060954","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T10:30:32Z","timestamp":1622025032000},"page":"954","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Prognostic Importance of Right Ventricular Longitudinal Strain in Patients with Cardiomyopathies, Connective Tissue Diseases, Coronary Artery Disease, and Congenital Heart Diseases"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6235-5152","authenticated-orcid":false,"given":"Marijana","family":"Tadic","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0165-9977","authenticated-orcid":false,"given":"Johannes","family":"Kersten","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoleta","family":"Nita","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonhard","family":"Schneider","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominik","family":"Buckert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgid","family":"Gonska","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominik","family":"Scharnbeck","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilman","family":"Dahme","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Imhof","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evgeny","family":"Belyavskiy","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin (Campus Virchow-Klinikum), 13353 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Cuspidi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, University of Milan-Bicocca, 20126 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Rottbauer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Ulm, Albert-Einstein Allee 23, 89081 Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1253\/circj.CJ-12-1083","article-title":"Efficacy of right ventricular free-wall longitudinal speckle-tracking strain for predicing long-term outcome in patients with pulmonary hypertension","volume":"77","author":"Motoji","year":"2013","journal-title":"Circ. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1093\/ehjci\/jev069","article-title":"Bi-ventricular contractile reserve offers an incremental prognostic value for patients with dilated cardiomyopathy","volume":"16","author":"Matsumoto","year":"2015","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"21908","DOI":"10.1038\/s41598-020-78945-4","article-title":"Prevalence, functional characteristics, and clinical significance of right ventricular involvement in patients with hypertrophic cardiomyopathy","volume":"10","author":"Seo","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jcmg.2018.01.012","article-title":"The prognostic value of right ventricular deformation imaging in early arrhythmogenic right ventricular cardiomyopathy","volume":"12","author":"Mast","year":"2019","journal-title":"JACC Cardiovasc. Imaging"},{"doi-asserted-by":"crossref","unstructured":"Huntjens, P.R., Zhang, K.W., Soyama, Y., Karmpalioti, M., Lenihan, D.J., and Gorcsan, J. (2021). Prognostic utility of echocardiographic atrial and ventricular strain imaging in patients with cardiac amyloidosis. JACC Cardiovasc. Imaging, 10.","key":"ref_6","DOI":"10.1016\/j.jcmg.2021.01.016"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1093\/ehjci\/jex147","article-title":"Mechanics and prognostic value of left and right ventricular dysfunction in patients with systemic sclerosis","volume":"19","author":"Saito","year":"2018","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jcmg.2014.10.011","article-title":"Impaired RV global longitudinal strain is associated with poor long-term clinical outcomes in patients with acute inferior STEMI","volume":"8","author":"Park","year":"2015","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1007\/s00330-016-4729-0","article-title":"The prognostic value of right ventricular long axis strain in non-ischaemic dilated cardiomyopathies using standard cardiac magnetic resonance imaging","volume":"27","author":"Arenja","year":"2017","journal-title":"Eur. Radiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"161","DOI":"10.21037\/cdt.2020.01.03","article-title":"The prognostic value of right ventricular deformation derived from cardiac magnetic resonance tissue tracking for all-cause mortality in light-chain amyloidosis patients","volume":"10","author":"Liu","year":"2020","journal-title":"Cardiovasc. Diagn. Ther."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1016\/j.ejrad.2013.10.006","article-title":"Italian registry of cardiac magnetic resonance","volume":"83","author":"Francone","year":"2014","journal-title":"Eur. J. Radiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1111\/j.1540-8159.2009.02434.x","article-title":"Right ventricular myocardial function in patients with either idiopathic or ischemic dilated cardiomyopathy without clinical sign of right heart failure: Effects of cardiac resynchronization therapy","volume":"32","author":"Salerno","year":"2009","journal-title":"Pacing Clin. Electrophysiol."},{"key":"ref_13","first-page":"87","article-title":"Right ventricular systolic echocardiographic parameters in dilated cardiomyopathy and prognosis","volume":"95","author":"Zairi","year":"2017","journal-title":"Tunis Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/jcu.22627","article-title":"Short-term effects of levosimendan on strain\/strain rate markers in patients with nonischemic dilated cardiomyopathy","volume":"46","year":"2018","journal-title":"J. Clin. Ultrasound"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/ehjci\/jez015","article-title":"The prognostic value of 2D strain in assessment of the right ventricle in patients with dilated cardiomyopathy","volume":"20","author":"Seo","year":"2019","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1093\/ehjci\/jex187","article-title":"Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy","volume":"19","author":"Moneghetti","year":"2018","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"doi-asserted-by":"crossref","unstructured":"Liu, T., Gao, Y., Wang, H., Zhou, Z., Wang, R., Chang, S.S., Liu, Y., Sun, Y., Rui, H., and Yang, G. (2020). Association between right ventricular strain and outcomes in patients with dilated cardiomyopathy. Heart, 2.","key":"ref_17","DOI":"10.1136\/heartjnl-2020-317949"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1365-2559.1995.tb00267.x","article-title":"Hypertrophic cardiomyopathy \u2013pathology and pathogenesis","volume":"26","author":"Davies","year":"1995","journal-title":"Histopathology"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1136\/hrt.44.4.433","article-title":"Histopathological specificity of hypertrophic obstructive cardiomyopathy. Myocardial fibre disarray and myocardial fibrosis","volume":"44","author":"Lie","year":"1980","journal-title":"Br. Heart J."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0735-1097(88)90101-5","article-title":"Echocardiographic measurement of right ventricular wall thickness in hypertrophic cardiomyopathy: Relation to clinical and prognostic features","volume":"11","author":"McKenna","year":"1988","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.amjcard.2007.05.061","article-title":"Right ventricular involvement in hypertrophic cardiomyopathy","volume":"100","author":"Maron","year":"2007","journal-title":"Am. J. Cardiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.echo.2015.07.015","article-title":"Right ventricular remodeling, its correlates, and its clinical impact in hypertrophic cardiomyopathy","volume":"28","author":"Beladan","year":"2015","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/ejechocard\/jeq007","article-title":"Right ventricular myocardial involvement in either physiological or pathological left ventricular hypertrophy: An ultrasound speckle-tracking two-dimensional strain analysis","volume":"11","author":"Caso","year":"2010","journal-title":"Eur. J. Echocardiogr."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ijcard.2016.11.150","article-title":"Exercise speckle-tracking strain imaging demonstrates impaired right ventricular contractile reserve in hypertrophic cardiomyopathy","volume":"227","author":"Limongelli","year":"2017","journal-title":"Int. J. Cardiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"536","DOI":"10.5152\/akd.2014.5538","article-title":"Right ventricular function in hypertrophic cardiomyopathy: A speckle tracking echocardiography study","volume":"15","author":"Cincin","year":"2015","journal-title":"Anatol. J. Cardiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1007\/s10554-015-0722-y","article-title":"Comparison of right ventricular contractile abnormalities in hypertrophic cardiomyopathy versus hypertensive heart disease using two dimensional strain imaging: A cross-sectional study","volume":"31","author":"Afonso","year":"2015","journal-title":"Int. J. Cardiovasc. Imaging"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.amjcard.2019.05.021","article-title":"Prevalence and prognostic implications of right ventricular dysfunction in patients with hypertrophic cardiomyopathy","volume":"124","author":"Hiemstra","year":"2019","journal-title":"Am. J. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"6118","DOI":"10.1007\/s00330-020-06922-6","article-title":"Advanced myocardial characterization in hypertrophic cardiomyopathy: Feasibility of CMR-based feature tracking strain analysis in a case-control study","volume":"30","author":"Yang","year":"2020","journal-title":"Eur. Radiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1038\/s41598-020-58775-0","article-title":"Assessing right ventricular deformation in hypertrophic cardiomyopathy patients with preserved right ventricular ejection fraction: A 3.0-T cardiovascular magnetic resonance study","volume":"10","author":"Li","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ijcard.2019.08.010","article-title":"The prognostic value of biventricular long axis strain using standard cardiovascular magnetic resonance imaging in patients with hypertrophic cardiomyopathy","volume":"294","author":"Yang","year":"2019","journal-title":"Int. J. Cardiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/eurheartj\/ehr069","article-title":"Right ventricular mechanical dispersion is related to malignant arrhythmias: A study of patients with arrhythmogenic right ventricular cardiomyopathy and subclinical right ventricular dysfunction","volume":"32","author":"Sarvari","year":"2011","journal-title":"Eur. Heart J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10554-018-1428-8","article-title":"Echocardiographic assessment of right ventricular function: Current clinical practice","volume":"35","author":"Schneider","year":"2019","journal-title":"Int. J. Cardiovasc. Imaging"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1530\/ERP-16-0028","article-title":"A meta-analysis for echocardiographic assessment of right ventricular structure and function in ARVC","volume":"3","author":"Qasem","year":"2016","journal-title":"Echo Res. Pract."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e015016","DOI":"10.1161\/JAHA.119.015016","article-title":"Right ventricular strain predicts structural disease progression in patients with arrhythmogenic right ventricular cardiomyopathy","volume":"9","author":"Malik","year":"2020","journal-title":"J. Am. Heart Assoc."},{"doi-asserted-by":"crossref","unstructured":"Kirkels, F.P., Lie, \u00d8.H., Cramer, M.J., Chivulescu, M., Rootwelt-Norberg, C., Asselbergs, F.W., Teske, A.J., and Haugaa, K.H. (2021). Right ventricular functional abnormalities in arrhythmogenic cardiomyopathy: Association with life-threatening ventricular arrhythmias. JACC Cardiovasc. Imaging, 3.","key":"ref_35","DOI":"10.1016\/j.jcmg.2020.12.028"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e007693","DOI":"10.1161\/CIRCIMAGING.118.007693","article-title":"Association of echocardiographic parameters of right ventricular remodeling and myocardial performance with modified task force criteria in adolescents with arrhythmogenic right ventricular cardiomyopathy","volume":"12","author":"Pieles","year":"2019","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12968-014-0075-z","article-title":"Biventricular myocardial strain analysis in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) using cardiovascular magnetic resonance feature tracking","volume":"16","author":"Heermann","year":"2014","journal-title":"J. Cardiovasc. Magn. Reson."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e00364","DOI":"10.1161\/CIRCIMAGING.115.003647","article-title":"Right ventricular strain and dyssynchrony assessment in arrhythmogenic right ventricular cardiomyopathy: Cardiac magnetic resonance feature-tracking study","volume":"8","author":"Prati","year":"2015","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/jmri.25068","article-title":"Right ventricular strain by MR quantitatively identifies regional dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy","volume":"43","author":"Vigneault","year":"2016","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00392-019-01450-w","article-title":"Biventricular myocardial strain analysis using cardiac magnetic resonance feature tracking (CMR-FT) in patients with distinct types of right ventricular diseases comparing arrhythmogenic right ventricular cardiomyopathy (ARVC), right ventricular outflow-tract tachycardia (RVOT-VT), and Brugada syndrome (BrS)","volume":"108","author":"Heermann","year":"2019","journal-title":"Clin. Res. Cardiol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"e012989","DOI":"10.1161\/JAHA.119.012989","article-title":"Early left ventricular involvement detected by cardiovascular magnetic resonance feature tracking in arrhythmogenic right ventricular cardiomyopathy: The effects of left ventricular late gadolinium enhancement and right ventricular dysfunction","volume":"8","author":"Chen","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"ref_42","first-page":"jeaa088","article-title":"A head-to-head comparison of speckle tracking echocardiography and feature tracking cardiovascular magnetic resonance imaging in right ventricular deformation","volume":"27","author":"Taha","year":"2020","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"e007546","DOI":"10.1161\/CIRCIMAGING.118.007546","article-title":"Regional strain by cardiac magnetic resonance imaging improves detection of right ventricular scar compared with late gadolinium enhancement on a multimodality scar evaluation in patients with arrhythmogenic right ventricular cardiomyopathy","volume":"11","author":"Zghaib","year":"2018","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1080\/13506129.2016.1194264","article-title":"Prognostic value of right ventricular systolic function in cardiac amyloidosis","volume":"23","author":"Bodez","year":"2016","journal-title":"Amyloid"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.echo.2016.07.017","article-title":"Cumulative burden of myocardial dysfunction in cardiac amyloidosis assessed using four-chamber cardiac strain","volume":"29","author":"Kado","year":"2016","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.echo.2019.03.005","article-title":"Role of right ventricular strain measured by two-dimensional echocardiography in the diagnosis of cardiac amyloidosis","volume":"32","author":"Sanabria","year":"2019","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/ejechocard\/jer289","article-title":"Right ventricular function in AL amyloidosis: Characteristics and prognostic implication","volume":"13","author":"Cappelli","year":"2012","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1093\/ehjci\/jes009","article-title":"Comparison of right ventricular longitudinal strain imaging, tricuspid annular plane systolic excursion, and cardiac biomarkers for early diagnosis of cardiac involvement and risk stratification in primary systematic (AL) amyloidosis: A 5-year cohort study","volume":"13","author":"Bellavia","year":"2012","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jaccao.2020.09.002","article-title":"Assessment of left ventricular, right ventricular, and left atrial strain in light-chain amyloidosis","volume":"2","author":"Leedy","year":"2020","journal-title":"JACC CardioOncology"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"470","DOI":"10.21037\/cdt-20-181","article-title":"Left and right ventricular myocardial deformation and late gadolinium enhancement: Incremental prognostic value in amyloid light-chain amyloidosis","volume":"10","author":"Li","year":"2020","journal-title":"Cardiovasc. Diagn. Ther."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/jmri.27200","article-title":"Prognostic value of right ventricular dysfunction in patients with al amyloidosis: Comparison of different techniques by cardiac magnetic resonance","volume":"52","author":"Wan","year":"2020","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1701436","DOI":"10.1183\/13993003.01436-2017","article-title":"Right ventricular longitudinal strain is diminished in systemic sclerosis compared with idiopathic pulmonary arterial hypertension","volume":"50","author":"Mukherjee","year":"2017","journal-title":"Eur. Respir. J."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/jcu.22552","article-title":"Systemic sclerosis impacts right heart and cardiac autonomic nervous system","volume":"46","author":"Tadic","year":"2018","journal-title":"J. Clin. Ultrasound"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/CIRCIMAGING.115.003792","article-title":"Unique abnormalities in right ventricular longitudinal strain in systemic sclerosis patients","volume":"9","author":"Mukherjee","year":"2016","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s00059-014-4113-2","article-title":"Right ventricular and atrial functions in systemic sclerosis patients without pulmonary hypertension. Speckle-tracking echocardiographic study","volume":"40","author":"Durmus","year":"2015","journal-title":"Herz"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s10554-018-1299-z","article-title":"Echocardiographic assessment of regional right ventricular systolic function using two-dimensional strain echocardiography and evaluation of the predictive ability of longitudinal 2D-strain imaging for pulmonary arterial hypertension in systemic sclerosis patients","volume":"34","author":"Hekimsoy","year":"2018","journal-title":"Int. J. Cardiovasc. Imaging"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/cpf.12561","article-title":"Decreased biventricular longitudinal strain in patients with systemic sclerosis is mainly caused by pulmonary hypertension and not by systemic sclerosis per se","volume":"39","author":"Lindholm","year":"2019","journal-title":"Clin. Physiol. Funct. Imaging"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1164\/rccm.201704-0789LE","article-title":"Improvement in Right Ventricular Strain with Ambrisentan and Tadalafil Upfront Therapy in Scleroderma-associated Pulmonary Arterial Hypertension","volume":"197","author":"Mercurio","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/acr2.1037","article-title":"Systolic dysfunction in systemic sclerosis: Prevalence and prognostic implications","volume":"1","author":"Andreassen","year":"2019","journal-title":"ACR Open Rheumatol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1177\/0961203314563135","article-title":"Subclinical right ventricle systolic dysfunction in childhood-onset systemic lupus erythematosus: Insights from two-dimensional speckle-tracking echocardiography","volume":"24","author":"Leal","year":"2015","journal-title":"Lupus"},{"key":"ref_61","first-page":"75","article-title":"Early assessment of right ventricular function in systemic lupus erythematosus patients using strain and strain rate imaging","volume":"111","author":"Luo","year":"2018","journal-title":"Arq. Bras. Cardiol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1177\/0961203319833786","article-title":"Three-dimensional echocardiographic evaluation of the right ventricle in patients with uncomplicated systemic lupus erythematosus","volume":"28","author":"Buonauro","year":"2019","journal-title":"Lupus"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ejim.2019.12.033","article-title":"Speckle tracking echocardiography in patients with systemic lupus erythematosus: A meta-analysis","volume":"73","author":"Forte","year":"2020","journal-title":"Eur. J. Intern. Med."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.crad.2019.09.136","article-title":"Biventricular tissue tracking demonstrating associations between left ventricular myocardial extracellular volume, pulmonary artery pressure, and reduced right ventricular ejection fraction in patients with systemic lupus erythematosus using cardiovascular MRI","volume":"75","author":"Wu","year":"2020","journal-title":"Clin. Radiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s10554-014-0585-7","article-title":"Assessment of right ventricular functional recovery after acute myocardial infarction by 2D speckle-tracking echocardiography","volume":"31","author":"Huttin","year":"2015","journal-title":"Int. J. Cardiovasc. Imaging"},{"doi-asserted-by":"crossref","unstructured":"Awad, E.M.L., Mahmoud, A.H., Maghrby, K.S., Taha, N.M., and Ibrahim, A.M. (2020). Short-term prognostic value of TAPSE, RVFAC and Tricuspid S\u2019 wave peak systolic velocity after first acute myocardial infarction. BMC Res Notes, 13.","key":"ref_66","DOI":"10.1186\/s13104-020-05040-2"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.echo.2015.11.015","article-title":"Association of decreased right ventricular strain with worse survival in non-acute coronary syndrome angina","volume":"29","author":"Chang","year":"2016","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1161\/CIRCIMAGING.109.914366","article-title":"Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention","volume":"3","author":"Antoni","year":"2010","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/ehjci\/jex184","article-title":"Right ventricular function assessed by 2D strain analysis predicts ventricular arrhythmias and sudden cardiac death in patients after acute myocardial infarction","volume":"19","author":"Risum","year":"2018","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/echo.14974","article-title":"Short- and long-term prognostic value of right ventricular function in patients with first acute ST elevation myocardial infarction treated by primary angioplasty","volume":"38","author":"Radwan","year":"2021","journal-title":"Echocardiography"},{"doi-asserted-by":"crossref","unstructured":"Stiermaier, T., Backhaus, S.J., Matz, J., Koschalka, A., Kowallick, J., de Waha-Thiele, S., Desch, S., Gutberlet, M., Hasenfu\u00df, G., and Thiele, H. (2020). Frequency and prognostic impact of right ventricular involvement in acute myocardial infarction. Heart, 2.","key":"ref_71","DOI":"10.1093\/ehjci\/ehaa946.1609"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10554-019-01753-z","article-title":"Right ventricular free wall strain predicts functional capacity in patients with repaired Tetralogy of Fallot","volume":"36","author":"Sandoval","year":"2020","journal-title":"Int. J. Cardiovasc. Imaging"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12968-018-0460-0","article-title":"Impact of surgical pulmonary valve replacement on ventricular strain and synchrony in patients with repaired tetralogy of Fallot: A cardiovascular magnetic resonance feature tracking study","volume":"20","author":"Balasubramanian","year":"2018","journal-title":"J. Cardiovasc. Magn. Reson."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.repc.2016.07.005","article-title":"Usefulness of right ventricular and right atrial two-dimensional speckle tracking strain to predict late arrhythmic events in adult patients with repaired Tetralogy of Fallot","volume":"36","author":"Branco","year":"2017","journal-title":"Rev. Port. Cardiol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1093\/ehjci\/jew277","article-title":"Cardiac remodelling amongst adults with various aetiologies of pulmonary arterial hypertension including Eisenmenger syndrome-implications on survival and the role of right ventricular transverse strain","volume":"18","author":"Moceri","year":"2017","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.cjca.2015.02.028","article-title":"Global longitudinal strain may identify preserved systolic function of the systemic right ventricle","volume":"31","author":"Kumor","year":"2015","journal-title":"Can. J. Cardiol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1007\/s00246-013-0713-5","article-title":"Right-ventricular global longitudinal strain may predict neo-aortic arch obstruction after Norwood\/Sano procedure in children with hypoplastic left heart syndrome","volume":"34","author":"Raucci","year":"2013","journal-title":"Pediatr. Cardiol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/954\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:08:17Z","timestamp":1760162897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,26]]},"references-count":77,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6]]}},"alternative-id":["diagnostics11060954"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics11060954","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2021,5,26]]}}}