{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T10:04:34Z","timestamp":1775556274178,"version":"3.50.1"},"reference-count":59,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Imaging of lymphoma is based on the use of 18F-fluorodeoxyglucose positron emission tomography\/computed tomography (18F-FDG-PET\/CT) and\/or contrast-enhanced CT, but concerns have been raised regarding radiation exposure related to imaging scans in patients with cancer, and its association with increased risk of secondary tumors in patients with lymphoma has been established. To date, lymphoproliferative disorders are among the most common indications to perform whole-body magnetic resonance imaging (MRI). Whole-body MRI is superior to contrast-enhanced CT for staging the disease, also being less dependent on histology if compared to 18F-FDG-PET\/CT. As well, it does not require exposure to ionizing radiation and could be used for the surveillance of lymphoma. The current role of whole-body MRI in the diagnostic workup in lymphoma is examined in the present review along with the diagnostic performance in staging, response assessment and surveillance of different lymphoma subtypes.<\/jats:p>","DOI":"10.3390\/diagnostics11061007","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T21:42:06Z","timestamp":1622497326000},"page":"1007","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Whole-Body Magnetic Resonance Imaging: Current Role in Patients with Lymphoma"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7989-9861","authenticated-orcid":false,"given":"Domenico","family":"Albano","sequence":"first","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi, Unit\u00e0 Operativa di Radiologia Diagnostica ed Interventistica, 20161 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Micci","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Patti","sequence":"additional","affiliation":[{"name":"Ematologia I, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, 90146 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Midiri","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Albano","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-948X","authenticated-orcid":false,"given":"Giuseppe","family":"Lo Re","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Grassedonio","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovico","family":"La Grutta","sequence":"additional","affiliation":[{"name":"Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities (ProMISE), University of Palermo, A.O.U.P. Giaccone, 90127 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Lagalla","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3913-6290","authenticated-orcid":false,"given":"Massimo","family":"Galia","sequence":"additional","affiliation":[{"name":"Sezione di Scienze Radiologiche, Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata, Universit\u00e0 degli Studi di Palermo, 90133 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3322\/caac.20138","article-title":"Cancer statistics, 2012","volume":"62","author":"Siegel","year":"2012","journal-title":"CA Cancer J. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e945","DOI":"10.1542\/peds.2013-3926","article-title":"Cancer Incidence Rates and Trends Among Children and Adolescents in the United States, 2001\u20132009","volume":"134","author":"Siegel","year":"2014","journal-title":"Pediatrics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1053\/j.seminhematol.2018.05.007","article-title":"Diagnosis and classification of lymphoma: Impact of technical advances","volume":"56","author":"Jaffe","year":"2019","journal-title":"Semin. Hematol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3322\/caac.21438","article-title":"Hodgkin lymphoma: A review and update on recent progress","volume":"68","author":"Shanbhag","year":"2018","journal-title":"CA Cancer J. Clin."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3348\/kjr.2017.18.1.54","article-title":"Diffuse Large B-Cell Lymphoma in the Era of Precision Oncology: How Imaging Is Helpful","volume":"18","author":"Shah","year":"2017","journal-title":"Korean J. Radiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/bjh.14728","article-title":"Prognostic models for primary mediastinal (thymic) B-cell lymphoma derived from 18-FDG PET\/CT quantitative parameters in the International Extranodal Lymphoma Study Group (IELSG) 26 study","volume":"178","author":"Ceriani","year":"2017","journal-title":"Br. J. Haematol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.blre.2012.09.004","article-title":"Management of indolent lymphoma: Where are we now and where are we going","volume":"26","author":"Lunning","year":"2012","journal-title":"Blood Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1182\/blood-2015-11-632745","article-title":"Is watch and wait still acceptable for patients with low-grade follicular lymphoma?","volume":"127","author":"Armitage","year":"2016","journal-title":"Blood"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1200\/JCO.2013.54.8800","article-title":"Recommendations for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The Lugano Classification","volume":"32","author":"Cheson","year":"2014","journal-title":"J. Clin. Oncol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e2017029","DOI":"10.4084\/mjhid.2017.029","article-title":"Fdg-Pet scan: A new paradigm for follicular lymphoma management","volume":"9","author":"Gallamini","year":"2016","journal-title":"Mediterr. J. Hematol. Infect. Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/ijc.29433","article-title":"Frequency of surveillance computed tomography in non-Hodgkin lymphoma and the risk of secondary primary malignancies: A nationwide population-based study","volume":"137","author":"Chien","year":"2015","journal-title":"Int. J. Cancer"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1148\/radiol.2511081300","article-title":"Whole-Body PET\/CT Scanning: Estimation of Radiation Dose and Cancer Risk","volume":"251","author":"Huang","year":"2009","journal-title":"Radiology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s11547-020-01242-7","article-title":"Whole-body magnetic resonance imaging (WB-MRI) in oncology: An Italian survey","volume":"126","author":"Albano","year":"2021","journal-title":"La Radiol. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1080\/10428194.2018.1434881","article-title":"Current concepts in tumor imaging with whole-body MRI with diffusion imaging (WB-MRI-DWI) in multiple myeloma and lymphoma","volume":"59","author":"Stecco","year":"2018","journal-title":"Leuk. Lymphoma"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1200\/JCO.1989.7.11.1630","article-title":"Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin\u2019s disease: Cotswolds meeting","volume":"7","author":"Lister","year":"1989","journal-title":"J. Clin. Oncol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1200\/JCO.2012.42.4036","article-title":"Routine Bone Marrow Biopsy Has Little or No Therapeutic Consequence for Positron Emission Tomography\/Computed Tomography\u2013Staged Treatment-Naive Patients with Hodgkin Lymphoma","volume":"30","author":"Mylam","year":"2012","journal-title":"J. Clin. Oncol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1200\/JCO.2008.16.1513","article-title":"Role of [18F]Fluorodeoxyglucose Positron Emission Tomography Scan in the Follow-Up of Lymphoma","volume":"27","author":"Zinzani","year":"2009","journal-title":"J. Clin. Oncol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s11547-016-0658-x","article-title":"Whole-body MRI in patients with lymphoma: Collateral findings","volume":"121","author":"Galia","year":"2016","journal-title":"La Radiol. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1593\/neo.81328","article-title":"Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations","volume":"11","author":"Padhani","year":"2009","journal-title":"Neoplasia"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1182\/blood-2007-07-101899","article-title":"Imaging in staging of malignant lymphoma: A systematic review","volume":"111","author":"Kwee","year":"2008","journal-title":"Blood"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Morone, M., Bali, M.A., Tunariu, N., Messiou, C., Blackledge, M., Grazioli, L., and Koh, D.-M. (2017). Whole-Body MRI: Current Applications in Oncology. Am. J. Roentgenol., 209.","DOI":"10.2214\/AJR.17.17984"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/jmri.25826","article-title":"Solid bone tumors of the spine: Diagnostic performance of apparent diffusion coefficient measured using diffusion-weighted MRI using histology as a reference standard","volume":"47","author":"Pozzi","year":"2017","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.mri.2016.04.023","article-title":"Pitfalls in whole body MRI with diffusion weighted imaging performed on patients with lymphoma: What radiologists should know","volume":"34","author":"Albano","year":"2016","journal-title":"Magn. Reson. Imaging"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1158\/1078-0432.CCR-13-3355","article-title":"Evaluation of Diffusion-Weighted MRI for Pretherapeutic Assessment and Staging of Lymphoma: Results of a Prospective Study in 140 Patients","volume":"20","author":"Mayerhoefer","year":"2014","journal-title":"Clin. Cancer Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1007\/s00247-012-2616-7","article-title":"Dynamic contrast-enhanced MRI improves accuracy for detecting focal splenic involvement in children and adolescents with Hodgkin disease","volume":"43","author":"Punwani","year":"2013","journal-title":"Pediatr. Radiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1177\/0284185115571657","article-title":"Accuracy of whole-body MRI in the assessment of splenic involvement in lymphoma","volume":"57","author":"Littooij","year":"2015","journal-title":"Acta Radiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s10067-017-3604-y","article-title":"Gadolinium accumulation after contrast-enhanced magnetic resonance imaging: What rheumatologists should know","volume":"36","author":"Doniselli","year":"2017","journal-title":"Clin. Rheumatol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.dld.2017.04.010","article-title":"Gadolinium accumulation after contrast-enhanced magnetic resonance imaging: Which implications in patients with Crohn\u2019s disease?","volume":"49","author":"Savarino","year":"2017","journal-title":"Dig. Liver Dis."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.clinimag.2014.06.017","article-title":"Whole-body diffusion-weighted MRI for staging lymphoma at 3.0T: Comparative study with MR imaging at 1.5T","volume":"39","author":"Azzedine","year":"2015","journal-title":"Clin. Imaging"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.2147\/OTT.S148189","article-title":"Whole-body MRI versus 18F-FDG PET\/CT for pretherapeutic assessment and staging of lymphoma: A meta-analysis","volume":"11","author":"Wang","year":"2018","journal-title":"OncoTargets Ther."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1182\/asheducation.V2012.1.397.3798512","article-title":"Interim PET-CT in the management of diffuse large B-cell lymphoma","volume":"2012","author":"Moskowitz","year":"2012","journal-title":"Hematology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1002\/jmri.25439","article-title":"Whole-body MRI, FDG-PET\/CT, and bone marrow biopsy, for the assessment of bone marrow involvement in patients with newly diagnosed lymphoma","volume":"45","author":"Albano","year":"2017","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ejrad.2015.12.006","article-title":"Comparison between whole-body MRI with diffusion-weighted imaging and PET\/CT in staging newly diagnosed FDG-avid lymphomas","volume":"85","author":"Albano","year":"2016","journal-title":"Eur. J. Radiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1007\/s00330-010-1758-y","article-title":"Whole-body diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient mapping for staging patients with diffuse large B-cell lymphoma","volume":"20","author":"Lin","year":"2010","journal-title":"Eur. Radiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1258\/ar.2010.100246","article-title":"Whole-body diffusion-weighted imaging compared with FDG-PET\/CT in staging of lymphoma patients","volume":"52","author":"Abdulqadhr","year":"2011","journal-title":"Acta Radiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/jmri.24356","article-title":"Whole-body MRI, including diffusion-weighted imaging, for staging lymphoma: Comparison with CT in a prospective multicenter study","volume":"40","author":"Kwee","year":"2014","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.crad.2015.11.018","article-title":"Whole-body MRI with diffusion-weighted imaging: A valuable alternative to contrast-enhanced CT for initial staging of aggressive lymphoma","volume":"71","author":"Cirillo","year":"2016","journal-title":"Clin. Radiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/104794","article-title":"Staging of Primary Abdominal Lymphomas: Comparison of Whole-Body MRI with Diffusion-Weighted Imaging and18F-FDG-PET\/CT","volume":"2015","author":"Stecco","year":"2015","journal-title":"Gastroenterol. Res. Pr."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Stecco, A., Trisoglio, A., Soligo, E., Berardo, S., Sukhovei, L., and Carriero, A. (2018). Whole-Body MRI with Diffusion-Weighted Imaging in Bone Metastases: A Narrative Review. Diagnostics, 8.","DOI":"10.3390\/diagnostics8030045"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1007\/s00330-013-2835-9","article-title":"Whole-body MRI for the detection of bone marrow involvement in lymphoma: Prospective study in 116 patients and comparison with FDG-PET","volume":"23","author":"Adams","year":"2013","journal-title":"Eur. Radiol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/mpo.2950170512","article-title":"Bone marrow involvement in young patients with non-Hodgkin\u2019s lymphoma: The importance of multiple bone marrow samples for accurate staging","volume":"17","author":"Haddy","year":"2006","journal-title":"Med. Pediatr. Oncol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1200\/JCO.2007.11.6525","article-title":"Early Interim 2-[18F]Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography Is Prognostically Superior to International Prognostic Score in Advanced-Stage Hodgkin\u2019s Lymphoma: A Report From a Joint Italian-Danish Study","volume":"25","author":"Gallamini","year":"2007","journal-title":"J. Clin. Oncol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1200\/JCO.2017.75.2543","article-title":"Early Chemotherapy Intensification With Escalated BEACOPP in Patients With Advanced-Stage Hodgkin Lymphoma With a Positive Interim Positron Emission Tomography\/Computed Tomography Scan After Two ABVD Cycles: Long-Term Results of the GITIL\/FIL HD 0607 Trial","volume":"36","author":"Gallamini","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ejrad.2018.04.014","article-title":"Whole-body diffusion-weighted MR and FDG-PET\/CT in Hodgkin Lymphoma: Predictive role before treatment and early assessment after two courses of ABVD","volume":"103","author":"Albano","year":"2018","journal-title":"Eur. J. Radiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.ejrad.2014.05.027","article-title":"Very early indicators of response to systemic therapy in lymphoma patients based on alterations in water diffusivity\u2014A preliminary experience in 20 patients undergoing whole-body diffusion-weighted imaging","volume":"83","author":"Horger","year":"2014","journal-title":"Eur. J. Radiol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s00330-018-5445-8","article-title":"Whole-body MRI for staging and interim response monitoring in paediatric and adolescent Hodgkin\u2019s lymphoma: A comparison with multi-modality reference standard including 18F-FDG-PET-CT","volume":"29","author":"Latifoltojar","year":"2018","journal-title":"Eur. Radiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/RLI.0b013e3182087b03","article-title":"Whole-Body Diffusion-Weighted Imaging With Apparent Diffusion Coefficient Mapping for Treatment Response Assessment in Patients With Diffuse Large B-Cell Lymphoma","volume":"46","author":"Lin","year":"2011","journal-title":"Investig. Radiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1102\/1470-7330.2013.0006","article-title":"Whole-body diffusion-weighted magnetic resonance imaging at 3 Tesla for early assessment of treatment response in non-Hodgkin lymphoma: A pilot study","volume":"13","author":"Bevernage","year":"2013","journal-title":"Cancer Imaging"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1158\/1078-0432.CCR-14-2454","article-title":"Evaluation of Diffusion-Weighted Magnetic Resonance Imaging for Follow-up and Treatment Response Assessment of Lymphoma: Results of an 18F-FDG-PET\/CT\u2013Controlled Prospective Study in 64 Patients","volume":"21","author":"Mayerhoefer","year":"2015","journal-title":"Clin. Cancer Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1634\/theoncologist.2008-0285","article-title":"Survival Expectations of Patients Diagnosed with Hodgkin\u2019s Lymphoma in 2006\u20132010","volume":"14","author":"Brenner","year":"2009","journal-title":"Oncologist"},{"key":"ref_51","unstructured":"National Comprehesive Cancer Network (2018, July 07). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae) Hodg-Kin Lymphoma Ver. 3. Available online: https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx#hodgkin."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/hon.2439_39","article-title":"Whole-body diffusion-weighted MR imaging in lymphoma surveillance","volume":"35","author":"Rademaker","year":"2017","journal-title":"Hematol. Oncol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s00330-017-5071-x","article-title":"Whole body magnetic resonance in indolent lymphomas under watchful waiting: The time is now","volume":"28","author":"Galia","year":"2017","journal-title":"Eur. Radiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1007\/s00330-016-4535-8","article-title":"Osteonecrosis detected by whole body magnetic resonance in patients with Hodgkin Lymphoma treated by BEACOPP","volume":"27","author":"Albano","year":"2017","journal-title":"Eur. Radiol."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Colombo, A., Saia, G., Azzena, A., Rossi, A., Zugni, F., Pricolo, P., Summers, P., Marvaso, G., Grimm, R., and Bellomi, M. (2021). Semi-Automated Segmentation of Bone Metastases from Whole-Body MRI: Reproducibility of Apparent Diffusion Coefficient Measurements. Diagnostics, 11.","DOI":"10.3390\/diagnostics11030499"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Brancato, V., Aiello, M., Della Pepa, R., Basso, L., Garbino, N., Nicolai, E., Picardi, M., Salvatore, M., and Cavaliere, C. (2020). Automatic Prediction and Assessment of Treatment Response in Patients with Hodgkin\u2019s Lymphoma Using a Whole-Body DW-MRI Based Approach. Diagnostics, 10.","DOI":"10.3390\/diagnostics10090702"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"108737","DOI":"10.1016\/j.ejrad.2019.108737","article-title":"Fused high b-value diffusion weighted and T2-weighted MR images in staging of pediatric Hodgkin\u2019s lymphoma: A pilot study","volume":"121","author":"Spijkers","year":"2019","journal-title":"Eur. J. Radiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/jmri.26034","article-title":"Improving lymph node characterization in staging malignant lymphoma using first-order ADC texture analysis from whole-body diffusion-weighted MRI","volume":"48","author":"Wolter","year":"2018","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.acra.2016.01.012","article-title":"Differentiation of Diffuse Large B-cell Lymphoma from Follicular Lymphoma Using Texture Analysis on Conventional MR Images at 3.0 Tesla","volume":"23","author":"Wu","year":"2016","journal-title":"Acad. Radiol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/1007\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:09:37Z","timestamp":1760162977000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/1007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,31]]},"references-count":59,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6]]}},"alternative-id":["diagnostics11061007"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics11061007","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,31]]}}}