{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:48:24Z","timestamp":1789663704456,"version":"4.0.1"},"reference-count":77,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T00:00:00Z","timestamp":1622937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","award":["None"],"award-info":[{"award-number":["None"]}],"id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Cognitive decline affects the clinical course in patients with Parkinson\u2019s disease (PD) and contributes to a poor prognosis. However, little is known about the underlying network-level abnormalities associated with each cognitive domain. We aimed to identify the networks related to each cognitive domain in PD using resting-state functional magnetic resonance imaging (MRI). Forty patients with PD and 15 normal controls were enrolled. All subjects underwent MRI and the Mini-Mental State Examination. Furthermore, the cognitive function of patients with PD was assessed using the Montreal Cognitive Assessment (MoCA). We used independent component analysis of the resting-state functional MRI for functional segmentation, followed by reconstruction to identify each domain-related network, to predict scores in PD using multiple regression models. Six networks were identified, as follows: the visuospatial-executive-domain-related network (R2 = 0.54, p &lt; 0.001), naming-domain-related network (R2 = 0.39, p &lt; 0.001), attention-domain-related network (R2 = 0.86, p &lt; 0.001), language-domain-related network (R2 = 0.64, p &lt; 0.001), abstraction-related network (R2 = 0.10, p &lt; 0.05), and orientation-domain-related network (R2 = 0.64, p &lt; 0.001). Cerebellar lobule VII was involved in the visuospatial-executive-domain-related and attention-domain-related networks. These two domains are involved in the first three listed nonamnestic cognitive impairment in the diagnostic criteria for PD with dementia (PDD). Furthermore, Brodmann area 10 contributed most frequently to each domain-related network. Collectively, these findings suggest that cerebellar lobule VII may play a key role in cognitive impairment in nonamnestic types of PDD.<\/jats:p>","DOI":"10.3390\/diagnostics11061042","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T23:59:55Z","timestamp":1623023995000},"page":"1042","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The Cerebellum Is a Common Key for Visuospatial Execution and Attention in Parkinson\u2019s Disease"],"prefix":"10.3390","volume":"11","author":[{"given":"Wataru","family":"Sako","sequence":"first","affiliation":[{"name":"Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shotaro","family":"Haji","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Osaki","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuishin","family":"Izumi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.1093\/brain\/awv228","article-title":"Network localization of neurological symptoms from focal brain lesions","volume":"138","author":"Boes","year":"2015","journal-title":"Brain A J. Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bandl.2016.08.004","article-title":"Broca and Wernicke are dead, or moving past the classic model of language neurobiology","volume":"162","author":"Tremblay","year":"2016","journal-title":"Brain Lang."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1111\/epi.16098","article-title":"The epileptic network and cognition: What functional connectivity is teaching us about the childhood epilepsies","volume":"60","author":"Bear","year":"2019","journal-title":"Epilepsia"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.nicl.2018.03.013","article-title":"Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?","volume":"18","author":"Hohenfeld","year":"2018","journal-title":"Neuroimage. Clin."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.parkreldis.2018.12.016","article-title":"Resting-state fMRI in Parkinson\u2019s disease patients with cognitive impairment: A meta-analysis","volume":"62","author":"Wolters","year":"2019","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"4022","DOI":"10.1162\/jocn_a_00077","article-title":"Behavioral interpretations of intrinsic connectivity networks","volume":"23","author":"Laird","year":"2011","journal-title":"J. Cogn. Neurosci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1212\/WNL.0b013e31827689d6","article-title":"Default-mode network connectivity in cognitively unimpaired patients with Parkinson disease","volume":"79","author":"Tessitore","year":"2012","journal-title":"Neurology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"5658","DOI":"10.1002\/hbm.22577","article-title":"The default mode network is disrupted in Parkinson\u2019s disease with visual hallucinations","volume":"35","author":"Yao","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00415-014-7591-5","article-title":"Resting-state functional connectivity associated with mild cognitive impairment in Parkinson\u2019s disease","volume":"262","author":"Amboni","year":"2015","journal-title":"J. Neurol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/hbm.22622","article-title":"Cognitive impairment and resting-state network connectivity in Parkinson\u2019s disease","volume":"36","author":"Baggio","year":"2015","journal-title":"Hum. Brain Mapp."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1002\/hbm.23499","article-title":"Intra- and inter-network functional alterations in Parkinson\u2019s disease with mild cognitive impairment","volume":"38","author":"Peraza","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/s00415-018-8755-5","article-title":"Distinct manifestation of cognitive deficits associate with different resting-state network disruptions in non-demented patients with Parkinson\u2019s disease","volume":"265","author":"Kawabata","year":"2018","journal-title":"J. Neurol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jns.2018.10.003","article-title":"Resting-state network connectivity in cognitively unimpaired drug-na\u00efve patients with rigidity-dominant Parkinson\u2019s disease","volume":"395","author":"Hou","year":"2018","journal-title":"J. Neurol. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/hbm.23260","article-title":"Parkinson\u2019s disease-related network topographies characterized with resting state functional MRI","volume":"38","author":"Vo","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1038\/jcbfm.2015.118","article-title":"Parkinson\u2019s disease-related spatial covariance pattern identified with resting-state functional MRI","volume":"35","author":"Wu","year":"2015","journal-title":"J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1212\/WNL.0b013e3181f61311","article-title":"What predicts mortality in Parkinson disease?: A prospective population-based long-term study","volume":"75","author":"Forsaa","year":"2010","journal-title":"Neurology"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1093\/brain\/awq059","article-title":"Relationships between age and late progression of Parkinson\u2019s disease: A clinico-pathological study","volume":"133","author":"Kempster","year":"2010","journal-title":"Brain A J. Neurol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1136\/jnnp.2011.240366","article-title":"The natural history of treated Parkinson\u2019s disease in an incident, community based cohort","volume":"82","author":"Evans","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1136\/jnnp-2013-305277","article-title":"The CamPaIGN study of Parkinson\u2019s disease: 10-year outlook in an incident population-based cohort","volume":"84","author":"Mason","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1001\/jamaneurol.2014.1455","article-title":"APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease","volume":"71","author":"Mata","year":"2014","journal-title":"JAMA Neurol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.parkreldis.2014.02.001","article-title":"Clinical and pathologic presentation in Parkinson\u2019s disease by apolipoprotein e4 allele status","volume":"20","author":"Monsell","year":"2014","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/mds.27204","article-title":"APOE, thought disorder, and SPARE-AD predict cognitive decline in established Parkinson\u2019s disease","volume":"33","author":"Tropea","year":"2018","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/mds.24045","article-title":"Glucocerebrosidase mutations confer a greater risk of dementia during Parkinson\u2019s disease course","volume":"27","author":"Pagonabarraga","year":"2012","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/brain\/aws318","article-title":"Glucocerebrosidase mutations influence the natural history of Parkinson\u2019s disease in a community-based incident cohort","volume":"136","author":"Evans","year":"2013","journal-title":"Brain A J. Neurol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1159\/000094871","article-title":"Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson\u2019s disease dementia","volume":"22","author":"Mollenhauer","year":"2006","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/mds.22594","article-title":"Cerebrospinal tau, phospho-tau, and beta-amyloid and neuropsychological functions in Parkinson\u2019s disease","volume":"24","author":"Compta","year":"2009","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1136\/jnnp.2009.199950","article-title":"CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson\u2019s disease: The Norwegian ParkWest study","volume":"81","author":"Alves","year":"2010","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1002\/mds.23287","article-title":"CSF A\u03b2(42) and tau in Parkinson\u2019s disease with cognitive impairment","volume":"25","author":"Montine","year":"2010","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.parkreldis.2013.03.009","article-title":"Combined dementia-risk biomarkers in Parkinson\u2019s disease: A prospective longitudinal study","volume":"19","author":"Compta","year":"2013","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1212\/WNL.0000000000001098","article-title":"CSF biomarkers and clinical progression of Parkinson disease","volume":"84","author":"Hall","year":"2015","journal-title":"Neurology"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s12031-015-0647-x","article-title":"CSF \u03b2-Amyloid 1-42 Predicts Progression to Cognitive Impairment in Newly Diagnosed Parkinson Disease","volume":"58","author":"Terrelonge","year":"2016","journal-title":"J. Mol. Neurosci. Mn"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.ajpath.2013.12.007","article-title":"Cerebrospinal fluid \u03b1-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort","volume":"184","author":"Stewart","year":"2014","journal-title":"Am. J. Pathol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.parkreldis.2014.12.027","article-title":"CSF tau and tau\/A\u03b242 predict cognitive decline in Parkinson\u2019s disease","volume":"21","author":"Liu","year":"2015","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.parkreldis.2016.09.012","article-title":"Altered functional connectivity in the default mode network is associated with cognitive impairment and brain anatomical changes in Parkinson\u2019s disease","volume":"33","author":"Ojeda","year":"2016","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/mds.27233","article-title":"Global scales for cognitive screening in Parkinson\u2019s disease: Critique and recommendations","volume":"33","author":"Skorvanek","year":"2018","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: A clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/phar.1611","article-title":"Clinical Outcomes in Patients with Parkinson\u2019s Disease Treated with a Monoamine Oxidase Type-B inhibitor: A Cross-Sectional, Cohort Study","volume":"35","author":"Dashtipour","year":"2015","journal-title":"Pharmacotherapy"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/hbm.1048","article-title":"A method for making group inferences from functional MRI data using independent component analysis","volume":"14","author":"Calhoun","year":"2001","journal-title":"Hum. Brain Mapp."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1002\/hbm.20813","article-title":"Functional segmentation of the brain cortex using high model order group PICA","volume":"30","author":"Kiviniemi","year":"2009","journal-title":"Hum. Brain Mapp."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.neuroimage.2004.03.027","article-title":"Validating the independent components of neuroimaging time series via clustering and visualization","volume":"22","author":"Himberg","year":"2004","journal-title":"NeuroImage"},{"key":"ref_41","first-page":"1636","article-title":"Mapping functionally related regions of brain with functional connectivity MR imaging","volume":"21","author":"Cordes","year":"2000","journal-title":"Am. J. Neuroradiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/cercor\/bhs352","article-title":"Tracking whole-brain connectivity dynamics in the resting state","volume":"24","author":"Allen","year":"2014","journal-title":"Cereb. Cortex"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"7209","DOI":"10.1073\/pnas.0811879106","article-title":"Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele","volume":"106","author":"Filippini","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1016\/j.neuroimage.2010.10.025","article-title":"Scaled subprofile modeling of resting state imaging data in Parkinson\u2019s disease: Methodological issues","volume":"54","author":"Spetsieris","year":"2011","journal-title":"NeuroImage"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/mds.21507","article-title":"Clinical diagnostic criteria for dementia associated with Parkinson\u2019s disease","volume":"22","author":"Emre","year":"2007","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"872487","DOI":"10.1155\/2015\/872487","article-title":"A Proposed Neurological Interpretation of Language Evolution","volume":"2015","author":"Ardila","year":"2015","journal-title":"Behav. Neurol."},{"key":"ref_47","first-page":"26","article-title":"Connectivity of BA46 involvement in the executive control of language","volume":"28","author":"Ardila","year":"2016","journal-title":"Psicothema"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e384","DOI":"10.1212\/WNL.0000000000008754","article-title":"Cognitive correlates of cerebellar resting-state functional connectivity in Parkinson disease","volume":"94","author":"Maiti","year":"2020","journal-title":"Neurology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/j.neuroimage.2007.01.020","article-title":"Dissociable correlates of two classes of retrieval processing in prefrontal cortex","volume":"35","author":"Ranganath","year":"2007","journal-title":"NeuroImage"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.cortex.2009.11.009","article-title":"Age differences in prefontal recruitment during verbal working memory maintenance depend on memory load","volume":"46","author":"Cappell","year":"2010","journal-title":"Cortex; A J. Devoted Study Nerv. Syst. Behav."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1093\/brain\/117.6.1271","article-title":"A graded task approach to the functional mapping of brain areas implicated in auditory-verbal memory","volume":"117","author":"Grasby","year":"1994","journal-title":"Brain A J. Neurol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0926-6410(00)00059-8","article-title":"Neuroanatomical discrimination between manipulating and maintaining processes involved in verbal working memory; a functional MRI study","volume":"11","author":"Tsukiura","year":"2001","journal-title":"Brain Res. Cogn. Brain Res."},{"key":"ref_53","first-page":"148","article-title":"Predominance of caudate nucleus lesions in acute ischaemic stroke patients with impairment in language and speech","volume":"23","author":"Roll","year":"2016","journal-title":"Eur. J. Neurol. Off. J. Eur. Fed. Neurol. Soc."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.neuroimage.2004.06.027","article-title":"Neural networks underlying endogenous and exogenous visual-spatial orienting","volume":"23","author":"Mayer","year":"2004","journal-title":"NeuroImage"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/nimg.1999.0525","article-title":"A PET investigation of the attribution of intentions with a nonverbal task","volume":"11","author":"Brunet","year":"2000","journal-title":"NeuroImage"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1167\/13.13.10","article-title":"When crowding of crowding leads to uncrowding","volume":"13","author":"Manassi","year":"2013","journal-title":"J. Vis."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1093\/brain\/aww175","article-title":"Visual dysfunction in Parkinson\u2019s disease","volume":"139","author":"Weil","year":"2016","journal-title":"Brain A J. Neurol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0926-6410(99)00052-X","article-title":"Different cortical activity in reading of Kanji words, Kana words and Kana nonwords","volume":"9","author":"Sakurai","year":"2000","journal-title":"Brain Res. Cogn. Brain Res."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/cercor\/bhp157","article-title":"Distinct and overlapping functional zones in the cerebellum defined by resting state functional connectivity","volume":"20","author":"Beckmann","year":"2010","journal-title":"Cereb. Cortex"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1093\/cercor\/bhp135","article-title":"Segregated fronto-cerebellar circuits revealed by intrinsic functional connectivity","volume":"19","author":"Krienen","year":"2009","journal-title":"Cereb. Cortex"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/20178","article-title":"The role of the anterior prefrontal cortex in human cognition","volume":"399","author":"Koechlin","year":"1999","journal-title":"Nature"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0926-6410(98)00045-7","article-title":"Regional brain activity during tasks devoted to the central executive of working memory","volume":"7","author":"Collette","year":"1999","journal-title":"Brain Res. Cogn. Brain Res."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0028-3932(02)00327-5","article-title":"The role of the rostral frontal cortex (area 10) in prospective memory: A lateral versus medial dissociation","volume":"41","author":"Burgess","year":"2003","journal-title":"Neuropsychologia"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/S0028-3932(02)00169-0","article-title":"Prefrontal activity associated with working memory and episodic long-term memory","volume":"41","author":"Ranganath","year":"2003","journal-title":"Neuropsychologia"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/j.neuroimage.2007.09.043","article-title":"Functional coupling between anterior prefrontal cortex (BA10) and hand muscle contraction during intentional and imitative motor acts","volume":"39","author":"Babiloni","year":"2008","journal-title":"NeuroImage"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s00221-016-4841-z","article-title":"Abnormal connectivity in the sensorimotor network predicts attention deficits in traumatic brain injury","volume":"235","author":"Shumskaya","year":"2017","journal-title":"Exp. Brain Res."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s00234-015-1556-y","article-title":"Increased connectivity between sensorimotor and attentional areas in Parkinson\u2019s disease","volume":"57","author":"Onu","year":"2015","journal-title":"Neuroradiology"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/brain\/aws360","article-title":"The cerebellum in Parkinson\u2019s disease","volume":"136","author":"Wu","year":"2013","journal-title":"Brain A J. Neurol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jns.2019.03.022","article-title":"Differences in the intra-cerebellar connections and graph theoretical measures between Parkinson\u2019s disease and multiple system atrophy","volume":"400","author":"Sako","year":"2019","journal-title":"J. Neurol. Sci."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/mds.28012","article-title":"Identifying the Functional Brain Network of Motor Reserve in Early Parkinson\u2019s Disease","volume":"35","author":"Chung","year":"2020","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ana.23631","article-title":"Metabolic brain networks in translational neurology: Concepts and applications","volume":"72","author":"Niethammer","year":"2012","journal-title":"Ann. Neurol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"116627","DOI":"10.1016\/j.jns.2019.116627","article-title":"Differences in cerebellar perfusion between Parkinson\u2019s disease and multiple system atrophy","volume":"409","author":"Murakami","year":"2020","journal-title":"J. Neurol. Sci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/ana.24937","article-title":"Involvement of the cerebellum in Parkinson disease and dementia with Lewy bodies","volume":"81","author":"Seidel","year":"2017","journal-title":"Ann. Neurol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00002093-200101000-00005","article-title":"Clinical and pathologic features of two groups of patients with dementia with Lewy bodies: Effect of coexisting Alzheimer-type lesion load","volume":"15","author":"Hachinski","year":"2001","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1001\/archneur.59.1.43","article-title":"Research evaluation and prospective diagnosis of dementia with Lewy bodies","volume":"59","author":"Lopez","year":"2002","journal-title":"Arch. Neurol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1212\/01.WNL.0000065889.42856.F2","article-title":"Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies","volume":"60","author":"Merdes","year":"2003","journal-title":"Neurology"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","article-title":"Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium","volume":"89","author":"McKeith","year":"2017","journal-title":"Neurology"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/1042\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:11:24Z","timestamp":1760163084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/6\/1042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,6]]},"references-count":77,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6]]}},"alternative-id":["diagnostics11061042"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics11061042","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,6]]}}}