{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:08:12Z","timestamp":1791648492917,"version":"4.3.4"},"reference-count":61,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T00:00:00Z","timestamp":1623283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>The porcelain gallbladder condition describes gallbladder calcification. While gallbladder calcification is believed to increase the risk of developing gallbladder cancer, recent reports have shown that the malignancy risk is much lower than previously reported. Symptomatic patients with porcelain gallbladder should be recommended for cholecystectomy, but the management of asymptomatic patients is debatable. Based on recent evidence, prophylactic cholecystectomy is not routinely recommended in all patients with porcelain gallbladder. From the assessment of the current literature, there are three essential factors in the management of patients with porcelain gallbladder: (1) symptoms or complications of gallbladder disease, (2) calcification pattern and (3) patient age and comorbidities. Patients who do not undergo cholecystectomy should be educated about the symptoms of gallbladder diseases, and a thorough discussion is essential between patients and clinicians.<\/jats:p>","DOI":"10.3390\/diagnostics11061073","type":"journal-article","created":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T13:31:39Z","timestamp":1623331899000},"page":"1073","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Management of Porcelain Gallbladder, Its Risk Factors, and Complications: A Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2993-6091","authenticated-orcid":false,"given":"Masaya","family":"Morimoto","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, St. Luke\u2019s International Hospital, Tokyo 104-8560, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Matsuo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, St. Luke\u2019s International Hospital, Tokyo 104-8560, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyoshi","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, St. Luke\u2019s International Hospital, Tokyo 104-8560, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1067\/msy.2001.113888","article-title":"Carcinoma in the porcelain gallbladder: A relationship revisited","volume":"129","author":"Stephen","year":"2001","journal-title":"Surgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s11605-013-2170-0","article-title":"Porcelain gallbladder: A benign process or concern for malignancy?","volume":"17","author":"Schnelldorfer","year":"2013","journal-title":"J. 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