{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:25:12Z","timestamp":1792041912217,"version":"4.4.0"},"reference-count":16,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T00:00:00Z","timestamp":1628985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Oncocytic lipoadenoma of the salivary gland is a rare tumor that develops mainly in the parotid gland. We report a case of oncocytic lipoadenoma of the parotid gland in a 70-year-old woman. The tumor measured 30 \u00d7 20 mm and had a well-circumscribed tan-brown surface. The tumor was histologically composed of oncocytic and lipomatous lesions without atypia. In addition to the oncocytic lipoadenoma, a small lipomatous tumor, measuring 10 \u00d7 7 mm, was found in the resected parotid gland. Macroscopically, this tumor was yellow and indistinguishable from the parotid gland. Microscopically, the tumor was rich in fats and contained an area of conglomerated duct-like proliferation and salivary gland components. Therefore, the tumor was diagnosed as a non-oncocytic lipoadenoma with a sialoadenoma component. We report the first case of double component oncocytic and non-oncocytic lipoadenomas of the salivary gland.<\/jats:p>","DOI":"10.3390\/diagnostics11081478","type":"journal-article","created":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T21:43:55Z","timestamp":1629063835000},"page":"1478","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Complex Component of Oncocytic and Non-Oncocytic Lipoadenomas in the Parotid Gland: A Case Report"],"prefix":"10.3390","volume":"11","author":[{"given":"Fuyuki","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Diagnostic Pathology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka Prefecture 411-8777, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka Prefecture 411-8777, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Sugino","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka Prefecture 411-8777, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0046-8177(98)90125-3","article-title":"Oncocytic lipoadenoma of the submandibular gland","volume":"29","author":"Hirokawa","year":"1998","journal-title":"Hum. Pathol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s12105-014-0543-7","article-title":"Oncocytic lipoadenoma of the salivary gland: A clinicopathologic analysis of 7 cases and review of the literature","volume":"9","author":"Lau","year":"2015","journal-title":"Head Neck Pathol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.prp.2009.02.008","article-title":"Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis","volume":"206","author":"Ilie","year":"2010","journal-title":"Pathol. Res. Pr."},{"key":"ref_4","first-page":"1000","article-title":"Oncocytic lipoadenoma of the parotid gland: A report of a new case and review of the literature","volume":"5","author":"Mitsimponas","year":"2012","journal-title":"Int J. Clin. Exp. Pathol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/dc.24364","article-title":"A case of oncocytic lipoadenoma of the submandibular gland and its diagnostic cytology challenges","volume":"48","author":"Murshed","year":"2020","journal-title":"Diagn. Cytopathol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"144","DOI":"10.4132\/jptm.2014.02.10","article-title":"Oncocytic lipoadenoma: A rare case of parotid gland tumor and review of the literature","volume":"49","author":"Chi","year":"2015","journal-title":"J. Pathol. Transl. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/PAS.0b013e31826731e0","article-title":"Lipomatous salivary gland tumors: A series of 31 cases spanning their morphologic spectrum with emphasis on sialolipoma and oncocytic lipoadenoma","volume":"37","author":"Agaimy","year":"2013","journal-title":"Am. J. Surg. 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Study of its keratin profile","volume":"449","author":"Klieb","year":"2006","journal-title":"Virchows Arch."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s12105-018-0917-3","article-title":"Characterisation of DOG-1 Expression in Salivary Gland Tumours and Comparison with Myoepithelial Markers","volume":"13","author":"Khurram","year":"2019","journal-title":"Head Neck Pathol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/modpathol.2012.57","article-title":"DOG1: A novel marker of salivary acinar and intercalated duct differentiation","volume":"25","author":"Duvvuri","year":"2012","journal-title":"Mod. Pathol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1097\/DAD.0000000000001159","article-title":"Oncocytic Metaplasia in Melanocytic Tumors","volume":"40","author":"Ahn","year":"2018","journal-title":"Am. J. Derm."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s12105-015-0618-0","article-title":"Myoepithelial neoplasms of soft tissue: An updated review of the clinicopathologic, immunophenotypic, and genetic features","volume":"9","author":"Jo","year":"2015","journal-title":"Head Neck Pathol."},{"key":"ref_15","first-page":"731","article-title":"Polymorphous adenocarcinoma: An overview of immunohistochemical features and insights on molecular pathology","volume":"34","author":"Tasoulas","year":"2019","journal-title":"Histol. 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