{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T21:31:49Z","timestamp":1767994309112,"version":"3.49.0"},"reference-count":25,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Uterine involution assessments are critical for the prevention of postpartum hemorrhage. Various methods have been used worldwide. Methods: The PUUS (Postpartum Uterine Ultrasonographic Scale) method evaluates, by transabdominal ultrasonography, the length of the endometrium of the uterine cavity occupied by blood or debris, from grade 0 (no blood) to grade 4 (over three-quarters of the endometrial length occupied by blood\/debris). A total of 131 consecutive patients admitted for delivery in the Elena Doamna Obstetrics and Gynecology University Hospital in Iasi, Romania, were prospectively evaluated using the PUUS method. The mean age was 27.72 years old, and they were examined during the first 24\u201348 h after vaginal delivery, or in the first 48\u201372 h after cesarean delivery. For patients with a PUUS grade greater than 1, re-examination was preformed daily in the following days, until the PUUS grade decreased to 1 or 0. Results: By standardizing uterine involution in a numerical fashion, we precisely demonstrate that uterine involution varied with the method of delivery (vaginal\/cesarean) and with the number of vials of oxytocin received intrapartum, but not with the number of vials of ergometrine maleate received, and not with the origin of the parturient (rural\/urban).<\/jats:p>","DOI":"10.3390\/diagnostics11091731","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T08:04:23Z","timestamp":1632211463000},"page":"1731","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Importance of the Novel Postpartum Uterine Ultrasonographic Scale in Numerical Assessments of Uterine Involution Regarding Perinatal Maternal and Fetal Outcomes"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7386-0859","authenticated-orcid":false,"given":"Roxana","family":"Covali","sequence":"first","affiliation":[{"name":"Department of Radiology, Elena Doamna Obsterics and Gynecology University Hospital, 700398 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetra","family":"Socolov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Cuza Voda Obstetrics and Gynecology University Hospital, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9112-7039","authenticated-orcid":false,"given":"Alexandru","family":"Carauleanu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Cuza Voda Obstetrics and Gynecology University Hospital, 700038 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioana","family":"Pavaleanu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Elena Doamna Obstetrics and Gynecology University Hospital, 700398 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Akad","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucian Vasile","family":"Boiculese","sequence":"additional","affiliation":[{"name":"Department of Statistics, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8969-8016","authenticated-orcid":false,"given":"Razvan Vladimir","family":"Socolov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Elena Doamna Obstetrics and Gynecology University Hospital, 700398 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,21]]},"reference":[{"key":"ref_1","first-page":"436","article-title":"Diseases and complications of the puerperium","volume":"118","author":"Tauscher","year":"2021","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.1080\/14767058.2019.1571033","article-title":"Novel subtype of atonic postpartum hemorrhage: Dynamic computed tomography evaluation of bleeding characteristics and the uterine cavity","volume":"33","author":"Ikeda","year":"2020","journal-title":"J. Matern.-Fetal Neonatal Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/RCT.0000000000000791","article-title":"Use of postpartum magnetic resonance imaging for diagnosis and classification of retained placenta tissue","volume":"43","author":"Zhang","year":"2019","journal-title":"J. Comput. Assist. Tomogr."},{"key":"ref_4","first-page":"207","article-title":"The value of postpartum ultrasound for the diagnosis of retained products of conception: A systematic review","volume":"9","author":"Muys","year":"2017","journal-title":"Facts Views Vis. Obgyn"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1007\/s10140-021-01927-0","article-title":"Emergent postpartum pelvic sonography","volume":"28","author":"Kostrubiak","year":"2021","journal-title":"Emerg. Radiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"100318","DOI":"10.1016\/j.ajogmf.2021.100318","article-title":"Ultrasound evaluation of the uterus in the uncomplicated postpartum period: A systematic review","volume":"3","author":"Ucci","year":"2021","journal-title":"Am. J. Obstet. Gynecol. MFM"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1007\/s00261-020-02948-y","article-title":"Ultrasound features help identify patients who can undergo noninvasive management for suspected retained products of conception: A single institutional experience","volume":"46","author":"Vyas","year":"2021","journal-title":"Abdom. Radiol."},{"key":"ref_8","unstructured":"Gill, P., Patel, A., and Van Hook, J.W. (2021). Uterine Atony, StatPearls Publishing."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Committee on Practice Bulletins-Obstetrics (2017). Practice Bulletin No.183: Postpartum Hemorrhage. Obstet. Gynecol., 130, e168\u2013e186.","DOI":"10.1097\/AOG.0000000000002351"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Iba\u00f1ez-Lorente, C., Casans-Frances, R., Bellas-Cotan, S., and Mu\u00f1oz-Alameda, L. (2021). Implementation of a maternal early warning system during early postpartum. A prospective observational study. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0252446"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"100342","DOI":"10.1016\/j.ajogmf.2021.100342","article-title":"The interrater reliability and agreement of a 0 to 10 uterine tone score in cesarean delivery","volume":"3","author":"Cole","year":"2021","journal-title":"Am. J. Obstet. Gynecol MFM"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4103\/JMU.JMU_5_18","article-title":"Conservative management of infected postpartum uterine dehiscence after cesarean section","volume":"26","year":"2018","journal-title":"J. Med. Ultrasound"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"310","DOI":"10.15557\/JoU.2018.0045","article-title":"Comparison of postpartum sonographic findings after uneventful vaginal and cesarean section deliveries","volume":"18","author":"Cilingir","year":"2018","journal-title":"J. Ultrason."},{"key":"ref_14","first-page":"CD001808","article-title":"Prophylactic oxytocin for the thirs stage of labour top revent postpartum haemorrhage","volume":"4","author":"Salati","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/j.jogc.2019.02.126","article-title":"Maternal area of residence, socioeconomic status, and risk of adverse maternal and birth outcomes in adolescent mothers","volume":"41","author":"Amjad","year":"2019","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1046\/j.0960-7692.2001.00561.x","article-title":"Ultrasonic evaluation of the uterus and uterine cavity after normal, vaginal delivery","volume":"18","author":"Bekuretsion","year":"2001","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_17","first-page":"12","article-title":"Clinical and ultrasonographic study of uterine involution in postpartum physiology","volume":"88","author":"Buisson","year":"1993","journal-title":"Rev. Fr. Gynecol. Obstet."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1055\/s-0037-1601418","article-title":"Ultrasonographic evaluation of uterine involution in the early puerperum","volume":"39","author":"Kristoschek","year":"2017","journal-title":"Rev. Bras. Ginecol. Obstet."},{"key":"ref_19","first-page":"41","article-title":"Ultrasonography of the uterus after normal vaginal delivery","volume":"25","author":"Akasheh","year":"2004","journal-title":"Saudi Med. J."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1080\/14767058.2017.1333099","article-title":"Sonographic appearance of the uterus in the early puerperium in vaginal versus cesarean deliveries: A prospective study","volume":"31","author":"Bardin","year":"2018","journal-title":"J. Matern.-Fetal Neonatal Med."},{"key":"ref_21","first-page":"85","article-title":"Puerperal uterine involution: An echographic follow-up","volume":"57","author":"Gonzalez","year":"1992","journal-title":"Rev. Chil. Obstet. Ginecol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/14767050310001650798","article-title":"Ultrasound examination of the postpartum uterus: What is normal?","volume":"15","author":"Sokol","year":"2004","journal-title":"J. Matern.-Fetal Neonatal Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1046\/j.1469-0705.2000.00234.x","article-title":"Ultrasonographic evaluation of the postpartum uterus","volume":"16","author":"Edwards","year":"2000","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_24","first-page":"3","article-title":"Ultrasound evaluation of the postpartum endometrial cavity","volume":"60","author":"Fuller","year":"2015","journal-title":"J. Reprod. Med."},{"key":"ref_25","first-page":"661","article-title":"Cervical dilation and curettage in elective cesarean section. A retrospective analysis","volume":"27","author":"Berlit","year":"2013","journal-title":"In Vivo"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/9\/1731\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:02:40Z","timestamp":1760166160000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/11\/9\/1731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,21]]},"references-count":25,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9]]}},"alternative-id":["diagnostics11091731"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics11091731","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,21]]}}}