{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:39:53Z","timestamp":1760236793302,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:00:00Z","timestamp":1640304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Urachal cancer arises from an embryologic remnant of the urogenital sinus and allantois and accounts for approximately 1% of bladder malignancies. The most encountered histologic subtype is adenocarcinoma. We present a 76-year-old man suspected to have an advanced sigmoid cancer infiltrating nearby organs. A supplemental 18F-FDG PET\/CT showed high tracer uptake in a tumorous process coherent with the dome of the bladder wall involving the sigmoid colon. Cystoscopy revealed a normal bladder wall, except for a small edematous area in the anterior bladder. Biopsies from the sigmoid colon and transurethral resection from the bladder confirmed a urothelial carcinoma originating from the urachus.<\/jats:p>","DOI":"10.3390\/diagnostics12010031","type":"journal-article","created":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T08:38:46Z","timestamp":1640335126000},"page":"31","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["18F-FDG PET\/CT in a Case of Urothelial Carcinoma in the Urachus Presenting as Colon Cancer"],"prefix":"10.3390","volume":"12","author":[{"given":"Jeannette D.","family":"Andersen","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Department of Clinical Medicine, Clinical Cancer Research Center, Aalborg University, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Knud","family":"Fabrin","sequence":"additional","affiliation":[{"name":"Department of Urology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Pathology, Aalborg University Hospital, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9089-288X","authenticated-orcid":false,"given":"Helle D.","family":"Zacho","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark"},{"name":"Department of Clinical Medicine, Clinical Cancer Research Center, Aalborg University, 9000 Aalborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/MOU.0000000000000798","article-title":"18F-fluoro-2-deoxy-D-glucose positron emission tomography\/computed tomography in muscle-invasive bladder cancer","volume":"30","author":"Einerhand","year":"2020","journal-title":"Curr. Opin. Urol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.euf.2017.06.005","article-title":"Detection of Lymph Node Metastasis in Patients with Bladder Cancer using Maximum Standardised Uptake Value and (18)F-fluorodeoxyglucose Positron Emission Tomography\/Computed Tomography: Results from a High-volume Centre Including Long-term Follow-up","volume":"5","author":"Bouchelouche","year":"2019","journal-title":"Eur. Urol. Focus"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/PAP.0000000000000110","article-title":"Updates in the Pathologic Diagnosis and Classification of Epithelial Neoplasms of Urachal Origin","volume":"23","author":"Paner","year":"2016","journal-title":"Adv. Anat. Pathol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-5347(17)50167-6","article-title":"Malignant urachal lesions","volume":"131","author":"Sheldon","year":"1984","journal-title":"J. Urol."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Brierley, J.D., and Wittekind, M.K.G.E.C. (2017). TNM Classification of Malignant Tumours, Wiley-Blackwell. [8th ed.].","DOI":"10.1002\/9780471420194.tnmc26.pub3"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Wittekind, C., Anne Lee, J.D.B.E., and van Eycken, E. (2019). TNM Supplement: A Commentary on Uniform Use, Wiley-Blackwell. [5th ed.].","DOI":"10.1002\/9781119263975"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.3892\/ol.2014.2502","article-title":"Investigating urachal carcinoma for more than 15 years","volume":"8","author":"Chen","year":"2014","journal-title":"Oncol. Lett."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0090-4295(85)90112-8","article-title":"Urachal carcinoma","volume":"26","author":"Johnson","year":"1985","journal-title":"Urology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0046-8177(96)90063-5","article-title":"Prognostic factors in urachal adenocarcinoma. A study in 41 specimens of DNA status, proliferating cell-nuclear antigen immunostaining, and argyrophilic nucleolar-organizer region counts","volume":"27","author":"Nakanishi","year":"1996","journal-title":"Hum. Pathol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3892\/mco.2016.1082","article-title":"Urachal carcinoma: Report of two cases and review of the literature","volume":"6","author":"Quan","year":"2017","journal-title":"Mol. Clin. Oncol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00428-018-2467-1","article-title":"Urachal carcinoma: From gross specimen to morphologic, immunohistochemical, and molecular analysis","volume":"474","author":"Riva","year":"2019","journal-title":"Virchows Arch."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.urolonc.2016.04.012","article-title":"Clinical, prognostic, and therapeutic aspects of urachal carcinoma-A comprehensive review with meta-analysis of 1010 cases","volume":"34","author":"Szarvas","year":"2016","journal-title":"Urol. Oncol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"7308168","DOI":"10.1155\/2018\/7308168","article-title":"Biomarkers in Urachal Cancer and Adenocarcinomas in the Bladder: A Comprehensive Review Supplemented by Own Data","volume":"2018","author":"Reis","year":"2018","journal-title":"Dis. 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