{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:44:52Z","timestamp":1770140692131,"version":"3.49.0"},"reference-count":27,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T00:00:00Z","timestamp":1643068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Polish Minister of Science and Higher Education","award":["003\/ RID\/2018\/19"],"award-info":[{"award-number":["003\/ RID\/2018\/19"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>There is a great need for early diagnosis of ischemic heart disease (IHD), the most common cause of which is haemodynamic disorders caused mainly by obstructive atherosclerosis of the coronary arteries. The diagnosis of IHD is usually made with the use of functional tests, which include resting ECG (R) or examination of significant perfusion disorders during exercise using the SPECT method. Despite the fact that the ECG (R) test is commonly used in cardiological diagnostics, it has a limited diagnostic value, especially in people with a low probability of coronary artery disease (CAD). In order to increase the effectiveness of the ECG (R) examination, SATRO ECG software, based on the single fibres heart activity model (SFHAM), was used to evaluate the electrocardiograms. The introduction of new classifiers from the available medical data to the analysis made it possible to evaluate the diagnostic efficacy of SATRO ECG (TOT) in predicting significant perfusion disorders in the exercise SPECT (TOT 2). These disorders are most often caused by obstructive atherosclerosis of the coronary arteries, which is the main cause of CAD. The database of 316 patients (219 men and 97 women, aged 57 \u00b1 10 years) was analyzed using resting and stress ECG, perfusion scintigraphy performed using the SPECT method, and SATRO ECG analysis. The diagnostic efficacy parameters of SATRO ECG (TOT) in predicting significant perfusion abnormalities in the exercise-induced SPECT (TOT 2) study were: sensitivity, 99%; specificity, 91%; concordance, 96%; and positive, 96%, and negative, 97%, predictive values. The Kappa\u2013Cohen coefficient was 0.92, and the statistical significance coefficient was p &lt; 0.001. These results indicate a statistically significant agreement in the diagnosis of IHD in both diagnostic methods used.<\/jats:p>","DOI":"10.3390\/diagnostics12020297","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T20:38:58Z","timestamp":1643143138000},"page":"297","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative Analysis of the Diagnostic Effectiveness of SATRO ECG in the Diagnosis of Ischemia Diagnosed in Myocardial Perfusion Scintigraphy Performed Using the SPECT Method"],"prefix":"10.3390","volume":"12","author":[{"given":"\u0141ukasz Jerzy","family":"Janicki","sequence":"first","affiliation":[{"name":"Institute for Physico-Medical Research, Primax Medica S.A., 62-040 Puszczykowo, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4728-8817","authenticated-orcid":false,"given":"Wies\u0142aw","family":"Leo\u0144ski","sequence":"additional","affiliation":[{"name":"Institute of Physics, University of Zielona G\u00f3ra, 65-417 Zielona G\u00f3ra, Poland"},{"name":"Joint Laboratory of Optics of Palack\u00fd University and Institute of Physics of CAS, RCPTM, Faculty of Science, Palack\u00fd University, 77147 Olomouc, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy Stanis\u0142aw","family":"Janicki","sequence":"additional","affiliation":[{"name":"Institute for Physico-Medical Research, Primax Medica S.A., 62-040 Puszczykowo, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6492-1325","authenticated-orcid":false,"given":"Mateusz","family":"Nowotarski","sequence":"additional","affiliation":[{"name":"Institute of Physics, University of Zielona G\u00f3ra, 65-417 Zielona G\u00f3ra, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miros\u0142aw","family":"Dziuk","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Military Institute of Medicine, 04-141 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryszard","family":"Piotrowicz","sequence":"additional","affiliation":[{"name":"Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, National Institute of Cardiology Stefan Cardinal Wyszy\u0144ski, State Research Institute, 04-628 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41572-019-0106-z","article-title":"Atherosclerosis","volume":"5","author":"Libby","year":"2019","journal-title":"Nat. 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