{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:59:20Z","timestamp":1760151560609,"version":"build-2065373602"},"reference-count":12,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T00:00:00Z","timestamp":1649203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Amyloidoma of the chest wall is an uncommon entity, consisting of a solitary tumor-like deposit of amyloid. Until now, while rarely reported, it was mostly presented with back pain and swelling. Here, we report the first case of a chest wall amyloidoma initially presented with fever of unknown origin. Due to the rarity of the lesion as a primary entity, protein electrophoresis and long-term follow-up are required. In addition, patients undergoing long-term hemodialysis are particularly at risk for such acquired amyloidosis. However, soft-tissue tumors, considered as amyloidoma, is also rare in patients with long-term hemodialysis. For patients with a fever of unknown primary origin, clinicians should keep amyloidoma in mind, especially in high-risk populations.<\/jats:p>","DOI":"10.3390\/diagnostics12040906","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T05:11:34Z","timestamp":1649221894000},"page":"906","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Amyloidoma of the Chest Wall Presented with Fever of Unknown Origin"],"prefix":"10.3390","volume":"12","author":[{"given":"Hsien-Po","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan"},{"name":"Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shang-Feng","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan"},{"name":"Department of Life Science, Tunghai University, Taichung 40705, Taiwan"},{"name":"Department of Medicine, National Yang Ming University, Taipei 11221, Taiwan"},{"name":"Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung 40705, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/0003-4975(94)00907-O","article-title":"Primary amyloidoma of the chest wall","volume":"59","author":"Iannettoni","year":"1995","journal-title":"Ann. Thorac. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1510\/icvts.2008.178921","article-title":"Amyloidoma of the chest wall: A rare entity","volume":"7","author":"Fierens","year":"2008","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"bcr0120125552","DOI":"10.1136\/bcr.01.2012.5552","article-title":"Primary amyloidoma of chest wall\u2014A rare condition","volume":"2012","author":"Kumar","year":"2012","journal-title":"BMJ Case Rep."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1016\/j.athoracsur.2013.04.109","article-title":"Extended resection of a plasmocytoma of bone and an amyloidoma of the chest wall","volume":"96","author":"Safi","year":"2013","journal-title":"Ann. Thorac. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.4103\/0377-4929.191821","article-title":"Soft-tissue amyloidoma with associated plasmacytoma","volume":"59","author":"Dalal","year":"2016","journal-title":"Indian J. Pathol. Microbiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1111\/hdi.12791","article-title":"Hemodialysis-associated soft tissue amyloidomas of the chest and abdominal wall","volume":"24","author":"Nasir","year":"2020","journal-title":"Hemodial. Int."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.radcr.2021.11.048","article-title":"Primary nodular chest amyloidoma: A case report and review of literature","volume":"17","author":"Crain","year":"2022","journal-title":"Radiol. Case Rep."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"404","DOI":"10.4103\/0970-2113.142151","article-title":"Primary amyloidoma of lung treated with radiation: A rare case report","volume":"31","author":"Kapoor","year":"2014","journal-title":"Lung India"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4908","DOI":"10.1182\/blood.V114.22.4908.4908","article-title":"A case of insulin resistance secondary to insulin induced localized cutaneous amyloidosis","volume":"114","author":"Buadi","year":"2009","journal-title":"Blood"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"907","DOI":"10.2214\/AJR.05.0221","article-title":"Dialysis-related amyloidoma presenting as a bilateral gluteal mass","volume":"186","author":"Libicher","year":"2006","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/13506120903090783","article-title":"Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis","volume":"16","author":"Montagna","year":"2009","journal-title":"Amyloid"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1053\/j.ajkd.2006.05.009","article-title":"Genital beta2-microglobulin amyloidoma in a long-term dialysis patient","volume":"48","author":"Okuda","year":"2006","journal-title":"Am. J. Kidney Dis."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/4\/906\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:48:51Z","timestamp":1760136531000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/4\/906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,6]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4]]}},"alternative-id":["diagnostics12040906"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics12040906","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2022,4,6]]}}}