{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:26:20Z","timestamp":1783650380324,"version":"3.55.0"},"reference-count":27,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>A coexistance of liver cystic echinococcosis (CE) and hepatocellular carcinoma (HCC) is very rare. HCC is the leading cause of cancer-related mortality worldwide, while CE is a globally endemic zoonosis caused by the cestode tapeworm Echinococcus granulosus. The association between these two diseases is still not well-defined. A preoperative diagnosis may be challenging, especially if HCC and CE present as a single lesion and if atypical imaging features are present. Herein, we present a case of the patient that was initially diagnosed as an extensive necrotic tumor in the left liver lobe and highly suspicious of being HCC associated with peritumoral hematoma. Left hemihepatectomy was performed, and the histopathological findings showed the collision of two lesions: a hydatid cyst and HCC.<\/jats:p>","DOI":"10.3390\/diagnostics12071583","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T20:47:56Z","timestamp":1656535676000},"page":"1583","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hepatocellular Carcinoma Presenting Simultaneously with Echinococcal Cyst Mimicking a Single Liver Lesion in a Non-Cirrhotic Patient: A Case Report and Review of the Literature"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4826-0218","authenticated-orcid":false,"given":"Jelena Djoki\u0107","family":"Kova\u010d","sequence":"first","affiliation":[{"name":"Center for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No.2, 11000 Belgrade, Serbia"},{"name":"Faculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7525-7615","authenticated-orcid":false,"given":"Milica","family":"Mitrovi\u0107","sequence":"additional","affiliation":[{"name":"Center for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No.2, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Jankovi\u0107","sequence":"additional","affiliation":[{"name":"Center for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No.2, 11000 Belgrade, Serbia"},{"name":"Faculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marko","family":"Andrejevi\u0107","sequence":"additional","affiliation":[{"name":"Departament for Pathology, University Clinical Centre of Serbia, Pasterova No.2, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6790-7892","authenticated-orcid":false,"given":"Aleksandar","family":"Bogdanovi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, Serbia"},{"name":"Clinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No.6, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Predrag","family":"Zduji\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No.6, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uro\u0161","family":"\u0110in\u0111i\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No.6, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Dugali\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, Serbia"},{"name":"Clinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No.6, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1053\/j.gastro.2007.04.061","article-title":"Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis","volume":"132","author":"Rudolph","year":"2007","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1102\/1470-7330.2012.0044","article-title":"Imaging of hepatocellular carcinoma: Diagnosis, staging and treatment monitoring","volume":"12","author":"Hennedige","year":"2013","journal-title":"Cancer Imaging"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.3748\/wjg.v26.i17.2012","article-title":"Pearls and pitfalls in magnetic resonance imaging of hepatocellular carcinoma","volume":"26","author":"Kovac","year":"2020","journal-title":"World J. 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