{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T20:42:37Z","timestamp":1777149757826,"version":"3.51.4"},"reference-count":25,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Emergency Clinical Hospital Bucharest and University Politehnica of Bucharest","award":["33\/2021"],"award-info":[{"award-number":["33\/2021"]}]},{"name":"Emergency Clinical Hospital Bucharest and University Politehnica of Bucharest","award":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"],"award-info":[{"award-number":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"]}]},{"name":"EEA Grants 2014\u20132021","award":["33\/2021"],"award-info":[{"award-number":["33\/2021"]}]},{"name":"EEA Grants 2014\u20132021","award":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"],"award-info":[{"award-number":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"]}]},{"DOI":"10.13039\/501100006595","name":"Romanian National Authority for Scientific Research, CNCS-UEFISCDI","doi-asserted-by":"publisher","award":["33\/2021"],"award-info":[{"award-number":["33\/2021"]}],"id":[{"id":"10.13039\/501100006595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006595","name":"Romanian National Authority for Scientific Research, CNCS-UEFISCDI","doi-asserted-by":"publisher","award":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"],"award-info":[{"award-number":["PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)"]}],"id":[{"id":"10.13039\/501100006595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Most patients presenting in an emergency unit with acute coronary syndromes (ACS) (which include non-ST-elevation myocardial infarction (NSTEMI), ST-elevation MI (STEMI), and unstable angina) usually meet at least two cardiovascular risk factors, such as dyslipidemia, arterial hypertension, diabetes mellitus type 2, obesity, history of or current smoking, etc. Most ACS patients suffer from a type of dyslipidemia, and in addition to this there are ACS patients rushed into the emergency units for which the feeding status is unknown. Thus, we set out to evaluate the effect of fasting on 16 blood metabolite concentrations and 114 lipoprotein parameters on one control group and a group of statin-treated ACS patients hospitalized in a cardiovascular emergency unit, using Nuclear Magnetic Resonance (NMR) spectroscopy. The results indicated trends (in terms of number of cases, but not necessarily in terms of the magnitude of the effect) for as many as four metabolites and 48 lipoproteins. The effect was defined as a trend for results showing over 70% of the cases from either one or both groups that experienced parameter changes in the same direction (i.e., either increased or decreased). In terms of magnitude, the effect is rather low, leading to the overall conclusion that in cardiovascular (CV) emergency units, the blood samples analyzed in any feeding status would provide close results and very valuable information regarding prognosis and for fast decisions on patient\u2019s proper management.<\/jats:p>","DOI":"10.3390\/diagnostics12071675","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T21:19:28Z","timestamp":1657487968000},"page":"1675","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Lipoprofiling Assessed by NMR Spectroscopy in Patients with Acute Coronary Syndromes: Is There a Need for Fasting Prior to Sampling?"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4957-4684","authenticated-orcid":false,"given":"Laura-Adina","family":"St\u0103nciulescu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Emergency Clinical Hospital, 014461 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-1025","authenticated-orcid":false,"given":"Alexandru","family":"Scafa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Emergency Clinical Hospital, 014461 Bucharest, Romania"},{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050513 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4680-9185","authenticated-orcid":false,"given":"C\u0103t\u0103lin","family":"Duduianu","sequence":"additional","affiliation":[{"name":"\u201cC.D. Nenitescu\u201d Centre of Organic Chemistry, Romanian Academy, 060023 Bucharest, Romania"},{"name":"Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 011061 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raluca","family":"Stan","sequence":"additional","affiliation":[{"name":"Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 011061 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7022-8893","authenticated-orcid":false,"given":"Alina","family":"Nicolescu","sequence":"additional","affiliation":[{"name":"\u201cC.D. Nenitescu\u201d Centre of Organic Chemistry, Romanian Academy, 060023 Bucharest, Romania"},{"name":"\u201cPetru Poni\u201d Institute of Macromolecular Chemistry, Romanian Academy, 700487 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8206-5227","authenticated-orcid":false,"given":"Calin","family":"Deleanu","sequence":"additional","affiliation":[{"name":"\u201cC.D. Nenitescu\u201d Centre of Organic Chemistry, Romanian Academy, 060023 Bucharest, Romania"},{"name":"\u201cPetru Poni\u201d Institute of Macromolecular Chemistry, Romanian Academy, 700487 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1940-5262","authenticated-orcid":false,"given":"Maria","family":"Doroban\u021bu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050513 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"707889","DOI":"10.3389\/fcvm.2021.707889","article-title":"Gender differences in atherosclerotic vascular disease: From lipids to clinical outcomes","volume":"8","author":"Vakhtangadze","year":"2021","journal-title":"Front. Cardiovasc. 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