{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:39:02Z","timestamp":1787582342899,"version":"build-2736575974"},"reference-count":43,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T00:00:00Z","timestamp":1658275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"GFHC (Groupe Francophone d\u2019H\u00e9matologie Cellulaire)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Ring sideroblasts are commonly seen in myelodysplastic neoplasms and are a key condition for identifying distinct entities of myelodysplastic neoplasms according to the WHO classification. However, the presence of ring sideroblasts is not exclusive to myelodysplastic neoplasms. Ring sideroblasts are as well either encountered in non-clonal secondary acquired disorders, such as exposure to toxic substances, drug\/medicine, copper deficiency, zinc overload, lead poison, or hereditary sideroblastic anemias related to X-linked, autosomal, or mitochondrial mutations. This review article will discuss diseases associated with ring sideroblasts outside the context of myelodysplastic neoplasms. Knowledge of the differential diagnoses characterized by the presence of ring sideroblasts in bone marrow is essential to prevent any misdiagnosis, which leads to delayed diagnosis and subsequent management of patients that differ in the different forms of sideroblastic anemia.<\/jats:p>","DOI":"10.3390\/diagnostics12071752","type":"journal-article","created":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T11:22:24Z","timestamp":1658316144000},"page":"1752","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["When Ring Sideroblasts on Bone Marrow Smears Are Inconsistent with the Diagnosis of Myelodysplastic Neoplasms"],"prefix":"10.3390","volume":"12","author":[{"given":"Sandrine","family":"Girard","sequence":"first","affiliation":[{"name":"Laboratory of Hematology, Center of Biology and Pathology East, Hospices Civils de Lyon, 69500 Bron, France"},{"name":"French-Speaking Cellular Hematology Group, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Genevieve","sequence":"additional","affiliation":[{"name":"French-Speaking Cellular Hematology Group, 69500 Bron, France"},{"name":"Laboratory of Hematology, Angers University Hospital, 49100 Angers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Rault","sequence":"additional","affiliation":[{"name":"French-Speaking Cellular Hematology Group, 69500 Bron, France"},{"name":"Department of Biological Hematology, Tours University Hospital, 37081 Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile","family":"Fenneteau","sequence":"additional","affiliation":[{"name":"French-Speaking Cellular Hematology Group, 69500 Bron, France"},{"name":"Laboratory of Hematology, Robert Debr\u00e9 Hospital, APHP, 75019 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Lesesve","sequence":"additional","affiliation":[{"name":"French-Speaking Cellular Hematology Group, 69500 Bron, France"},{"name":"Laboratory of Hematology, Nancy University Hospital, 54000 Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,20]]},"reference":[{"key":"ref_1","first-page":"237","article-title":"Iron-staining erythrocytic inclusions with especial reference to acquired haemolytic anaemia","volume":"28","author":"Mc","year":"1947","journal-title":"Glasg. 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