{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:11:07Z","timestamp":1789711867882,"version":"4.0.1"},"reference-count":91,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Pseudopterygium is a non-progressive conjunctival adhesion to the peripheral cornea secondary to a corneal-limbus damage. According to the literature, the main etiology is a previous eye trauma. Nevertheless, this could be biased by the existence of other underdiagnosed causes of pseudopterygium, some of which may have severe consequences for the integrity of the eye and patient\u2019s life. This comprehensive literature review was performed based on a search on the PubMed and Google Scholar databases of relevant pseudopterygium published papers according to our current knowledge and seeks to gather the existing evidence about its diverse etiologies and clinical features, as well as to propose a diagnostic algorithm to simplify its correct approach.<\/jats:p>","DOI":"10.3390\/diagnostics12081843","type":"journal-article","created":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T23:37:29Z","timestamp":1659310649000},"page":"1843","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Pseudopterygium: An Algorithm Approach Based on the Current Evidence"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1288-3715","authenticated-orcid":false,"given":"Facundo","family":"Urbinati","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Hospital Regional Universitario de M\u00e1laga, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6952-5647","authenticated-orcid":false,"given":"Davide","family":"Borroni","sequence":"additional","affiliation":[{"name":"Department of Doctoral Studies, Riga Stradins University, LV-1007 Riga, Latvia"},{"name":"Advalia Vision, Cornea Research Unit, 20145 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Rodr\u00edguez-Calvo-de-Mora","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Regional Universitario de M\u00e1laga, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0450-7717","authenticated-orcid":false,"given":"Jos\u00e9-Mar\u00eda","family":"S\u00e1nchez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Physics of Condensed Matter, Optics Area, University of Seville, 41012 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Garc\u00eda-Lorente","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Regional Universitario de M\u00e1laga, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Zamorano-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital Regional Universitario de M\u00e1laga, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5901-2469","authenticated-orcid":false,"given":"Rahul","family":"Rachwani-Anil","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital de Antequera, 29200 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6929-3479","authenticated-orcid":false,"given":"Santiago","family":"Ortiz-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Departamento de Oftalmolog\u00eda, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Department of Surgery, University of Granada, 18011 Granada, Spain"},{"name":"Department of Ophthalmology, Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA, 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5148-7643","authenticated-orcid":false,"given":"Vito","family":"Romano","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, 25121 Brescia, Italy"},{"name":"Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L69 3BX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7464-2493","authenticated-orcid":false,"given":"Carlos","family":"Rocha-de-Lossada","sequence":"additional","affiliation":[{"name":"Departamento de Oftalmolog\u00eda, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Department of Ophthalmology, Qvision, Vithas, 04120 Almer\u00eda, Spain"},{"name":"Departament os Surgery, Ophthalmology Area, University of Seville, 41012 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1097\/ICO.0000000000002358","article-title":"Global Consensus on the Management of Limbal Stem Cell Deficiency","volume":"39","author":"Deng","year":"2020","journal-title":"Cornea"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jtos.2017.11.002","article-title":"The diagnosis of limbal stem cell deficiency","volume":"16","author":"Le","year":"2018","journal-title":"Ocul. 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