{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T05:18:06Z","timestamp":1762060686215,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Some neurotropic viruses induce specific lesions in the deep structures, such as basal ganglia and thalamus. These anatomical structures play an important role in initiating and maintaining different types of epileptic seizures. We present the case of a 25-year-old male, transferred to our clinic one week after the onset of the symptomatology, with a recent history of traveling to Turkey and Egypt. At the moment of his hospital admission, his symptoms included altered consciousness, agitation, and seizures. Shortly after, his state worsened, requiring intubation. Viral tick-borne encephalitis diagnoses were favored by the CSF (cerebrospinal fluid) analysis, EEG (Electroencephalography), MRI (magnetic resonance imaging) images presenting symmetric hyper signal in the basal ganglia, and IgM antibodies for anti-tick-borne encephalitis. These lesions persisted for several weeks, and the patient\u2019s seizures were polymorphic, originally generalized onset motor, generalized onset non-motor, and focal myoclonic. The patient achieved his independence, seizures decreasing both in intensity and frequency; the MRI images became almost normal. The reduction in antiepileptic doses was not followed by seizure recurrence.<\/jats:p>","DOI":"10.3390\/diagnostics12081888","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T21:52:48Z","timestamp":1659649968000},"page":"1888","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["MRI Evolution of a Patient with Viral Tick-Borne Encephalitis and Polymorphic Seizures"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1982-1066","authenticated-orcid":false,"given":"Carmen Adella","family":"Sirbu","sequence":"first","affiliation":[{"name":"Department of Neurology, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 010242 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantin","family":"Stefani","sequence":"additional","affiliation":[{"name":"Department No. 5, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Mitric\u0103","sequence":"additional","affiliation":[{"name":"Clinical Neurosciences Department, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Simona","family":"Toma","sequence":"additional","affiliation":[{"name":"Department of Radiology, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 010242 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelian Emil","family":"Ranetti","sequence":"additional","affiliation":[{"name":"Department No. 2, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8525-3554","authenticated-orcid":false,"given":"Any","family":"Docu-Axelerad","sequence":"additional","affiliation":[{"name":"Department No. 4, Faculty of Medicine, \u2018Ovidius\u2019 University of Constanta, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aida Mihaela","family":"Manole","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinical Ambulatory, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 010242 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ion","family":"Stefan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 010242 Bucharest, Romania"},{"name":"Department of Medico-Surgical and Prophylactic Disciplines, Titu Maiorescu University, 031593 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e00609-15","DOI":"10.1128\/genomeA.00609-15","article-title":"Complete Genome Sequences of Four European Subtype Strains of Tick-Borne Encephalitis Virus from Eastern Siberia, Russia","volume":"3","author":"Adelshin","year":"2015","journal-title":"Genome Announc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"430","DOI":"10.12998\/wjcc.v3.i5.430","article-title":"Tick-borne encephalitis: A review of epidemiology, clinical characteristics, and management","volume":"3","author":"Bogovic","year":"2015","journal-title":"World J. 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