{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:14:28Z","timestamp":1775790868695,"version":"3.50.1"},"reference-count":32,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"German Society of Ultrasound in Medicine and Biology (DEGUM)","award":["EUR 5000"],"award-info":[{"award-number":["EUR 5000"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>(1) Background: Computed tomography (CT) is considered mandatory for assessing the extent of pathologies in the paranasal sinuses (PNS) in chronic rhinosinusitis (CRS). However, there are few evidence-based data on the value of ultrasound (US) in CRS. This multicenter approach aimed to compare diagnostic imaging modalities in relation to findings during surgery. (2) Methods: 127 patients with CRS were included in this prospective multicenter study. Patients received preoperative US and CT scans. The sensitivity and specificity of CT and US were extrapolated from intraoperative data. (3) Results: CT scans showed the highest sensitivity (97%) and specificity (67%) in assessing CRS. Sensitivities of B-scan US were significantly lower regarding the maxillary sinus (88%), the ethmoid sinus (53%), and the frontal sinus (45%). The highest overall sensitivity was observed for assessing the pathology of the maxillary sinus. (4) Conclusions: We observed high accuracy with CT, confirming its importance in preoperative imaging in CRS. Despite the high US expertise of all investigators and a standardized examination protocol, the validity of CT was significantly higher than US. Ultrasound of the PNS sinuses is applicable in everyday clinical practice but lacks diagnostic accuracy. Nevertheless, it might serve as a complementary hands-on screening tool to directly correlate the clinical findings in patients with PNS disease.<\/jats:p>","DOI":"10.3390\/diagnostics12092065","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T02:04:32Z","timestamp":1661479472000},"page":"2065","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Multicenter Observational Study to Evaluate the Diagnostic Value of Sonography in Patients with Chronic Rhinosinusitis"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9648-8834","authenticated-orcid":false,"given":"Alessandro","family":"Bozzato","sequence":"first","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Saarland University Medical Center, Kirrbergerstra\u00dfe 100, 66421 Homburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8072-1438","authenticated-orcid":false,"given":"Christoph","family":"Arens","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, University Hospital Giessen, Klinikstra\u00dfe 29, 35392 Gie\u00dfen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5028-9282","authenticated-orcid":false,"given":"Maximilian","family":"Linxweiler","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Saarland University Medical Center, Kirrbergerstra\u00dfe 100, 66421 Homburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Bozzato","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Saarland University Medical Center, Kirrbergerstra\u00dfe 100, 66421 Homburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Jecker","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Plastic Head and Neck Surgery, Klinikum Bad Salzungen GmbH, Lindigallee 3, 36433 Bad Salzungen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregor","family":"Hilger","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Klinikum Stolberg, Jahnsdorfer Stra\u00dfe 7, 09366 Stollberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-J\u00fcrgen","family":"Welkoborsky","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Klinikum Nordstadt, Haltenhoffstr. 41, 30167 Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Zenk","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, University Hospital Augsburg, Sauerbruchstr. 6, 86179 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9057-7684","authenticated-orcid":false,"given":"Lukas","family":"Pillong","sequence":"additional","affiliation":[{"name":"Department for Otorhinolaryngology and Head and Neck Surgery, Saarland University Medical Center, Kirrbergerstra\u00dfe 100, 66421 Homburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin20.401","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"ref_2","first-page":"183","article-title":"Staging in rhinosinusitis","volume":"31","author":"Lund","year":"1993","journal-title":"Rhinology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1007\/s00117-007-1502-z","article-title":"Bildgebung der Nasennebenh\u00f6hlen (NNH) in der heutigen Zeit","volume":"47","author":"Dammann","year":"2007","journal-title":"Der Radiol."},{"key":"ref_4","first-page":"427","article-title":"A- and B-mode ultrasound diagnosis in diseases of the paranasal sinuses and soft tissues of the face","volume":"26","author":"Mann","year":"1986","journal-title":"Der Radiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1177\/019459988910700601.1","article-title":"B-mode ultrasonography of the paranasal sinuses compared with CT findings","volume":"107","author":"Gianoli","year":"1992","journal-title":"Otolaryngol. 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