{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T07:37:17Z","timestamp":1762760237476,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Placenta accreta spectrum (PAS) disorders are associated with high mortality and morbidity due to postpartum hemorrhage, hysterectomy, and organ injury, and a multidisciplinary team is required for an individualized case management. In this study, we assessed the diagnostic and prognostic accuracy of the most important ultrasonographic (US) and magnetic resonance imagining (MRI) markers for PAS disorders. Material and Methods: The study included 39 adult pregnant patients with at least one previous cesarean delivery and both US and MRI investigations for placenta previa evaluated at the tertiary maternity hospital \u2018Cuza Voda\u2019, Iasi, between 2019 and 2021. The following US signs were evaluated: intra-placental lacunae, loss of the retroplacental hypoechoic zone, myometrial thinning &lt; 1 mm, bladder wall interruption, placental bulging, bridging vessels, and the hypervascularity of the uterovesical or retroplacental space. The MRI signs that were evaluated were intra-placental dark T2 bands, placental bulging, loss of the retroplacental hypointense line on T2 images, myometrial thinning, bladder wall interruption, focal exophytic placental mass, and abnormal vascularization of the placental bed. Results: The US and MRI signs analyzed in our study presented adequate sensitivities and specificities for PAS, but no sign proved to be a useful predictor by itself. The presence of three or more US markers for accretion was associated with a sensitivity of 84.6.6% and a specificity of 92.3% (p &lt; 0.001). The presence of three or more MRI signs supplemented these results and were associated with a sensitivity of 92.3% and a specificity of 61.5% for predicting PAS (p &lt; 0.001). Moreover, US and MRI findings were correlated with FIGO grading and severity of PAS. Conclusions: Even though no US or MRI finding alone can predict PAS with high sensitivity and specificity, our study proves that the presence of three or more imagistic signs could significantly increase the diagnostic accuracy of this condition. Furthermore, US and MRI could be useful tools for evaluating prognostic and perinatal planning.<\/jats:p>","DOI":"10.3390\/diagnostics12092130","type":"journal-article","created":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T21:27:17Z","timestamp":1662067637000},"page":"2130","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Predicting Placenta Accreta Spectrum Disorders in a Cohort of Pregnant Patients in the North-East Region of Romania\u2014Diagnostic Accuracy of Ultrasound and Magnetic Resonance Imaging"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1955-3521","authenticated-orcid":false,"given":"Raluca Maria","family":"Haba","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5310-356X","authenticated-orcid":false,"given":"Anda Ioana","family":"Pristavu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria-Luiza","family":"Cobzeanu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Imaging University Hospital \u201cSf.Spiridon\u201d Bd.Independentei 1, 700106 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9112-7039","authenticated-orcid":false,"given":"Alexandru","family":"Carauleanu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioana","family":"Sadiye Scripcariu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4718-392X","authenticated-orcid":false,"given":"Ingrid Andrada","family":"Vasilache","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorina Adelina","family":"Minciuna","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragos","family":"Negru","sequence":"additional","affiliation":[{"name":"Department of Radiology, Imaging University Hospital \u201cSf.Spiridon\u201d Bd.Independentei 1, 700106 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0979-0200","authenticated-orcid":false,"given":"Demetra Gabriela","family":"Socolov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u2018Grigore T. Popa\u2019 University of Medicine and Pharmacy, 700115 Iasi, Romania"},{"name":"Obstetrics and Gynaecology Department, \u201cCuza Voda\u201d Obstetrics and Gynecology University Hospital, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ajog.2017.05.067","article-title":"Placenta accreta spectrum: Pathophysiology and evidence-based anatomy for prenatal ultrasound imaging","volume":"218","author":"Jauniaux","year":"2018","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0002-9378(16)34741-X","article-title":"Placenta accreta: The adherent or invasive placenta","volume":"95","author":"Luke","year":"1966","journal-title":"Am. J. Obstet. 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Radiol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/9\/2130\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:22:00Z","timestamp":1760142120000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/9\/2130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":42,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,9]]}},"alternative-id":["diagnostics12092130"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics12092130","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2022,9,1]]}}}