{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T06:41:14Z","timestamp":1762065674708,"version":"build-2065373602"},"reference-count":15,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Intrauterine devices (IUDs) are very common as a method of birth control. By adding progesterone (levonorgestrel), a decrease in the risk of complications has been documented, including the risk of perforation. Even though only a few complications have been described, adjacent organs may be involved in the case of migration\u2014a life-threatening situation. A 45-year-old G4P2 woman was seen in our clinic for LNg-IUD removal, according to the medical instructions. Her main complaints were abdominal discomfort, low back pain, and recurrent menorrhagia. A \u201clost\u201d IUD was initially suspected; the patient confirmed the detection and removal of the control strings, and a subsequent discussion related to delayed transmural migration of the IUD being followed. The ultrasonography revealed the migration of the IUD to the uterine cervix and size-decreased uterine fibroids, confirming the effectiveness of the LNg-IUD. The MRI and ultrasonography being useless, a subsequent X-ray and CT scan were requested, both confirming a myometrium-positioned IUD, adjacent to the serosa and lumbosacral plexus. Even though the IUD is considered a safe device with reversible effect, it can be associated with severe morbidity, with an ultrasound follow-up being required. For more precise detection of the IUD, we strongly recommend an X-ray or CT scan examination, followed by safe removal.<\/jats:p>","DOI":"10.3390\/diagnostics12092227","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T22:11:10Z","timestamp":1663279870000},"page":"2227","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An Interesting Image of Transmural Migration of a Levonorgestrel-Releasing Intrauterine Device (LNg-IUD)"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1596-6353","authenticated-orcid":false,"given":"Melinda-Ildiko","family":"Mitranovici","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Emergency County Hospital Hunedoara, 14 Victoriei Street, 331057 Hunedoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7024-2916","authenticated-orcid":false,"given":"Diana Maria","family":"Chiorean","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian-Hora\u021biu","family":"Sab\u0103u","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"},{"name":"Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5985-2433","authenticated-orcid":false,"given":"Iuliu-Gabriel","family":"Cocuz","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"},{"name":"Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreea C\u0103t\u0103lina","family":"Tinca","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"},{"name":"Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela Cornelia","family":"M\u0103rginean","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"},{"name":"Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C\u0103t\u0103lina","family":"Popelea","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Traian","family":"Irimia","sequence":"additional","affiliation":[{"name":"School of Medicine, \u201cGeorge Emil Palade\u201d University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raluca","family":"Moraru","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cGeorge Emil Palade\u201d University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu","family":"M\u0103rginean","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cGeorge Emil Palade\u201d University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marius Lucian","family":"Craina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izabella","family":"Petre","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1084-2714","authenticated-orcid":false,"given":"Elena Silvia","family":"Bernad","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ion","family":"Petre","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics and Biostatistics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 2 Eftimie Murgu Sq, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ovidiu Simion","family":"Cotoi","sequence":"additional","affiliation":[{"name":"Department of Pathology, County Clinical Hospital of Targu Mures, 540072 Targu Mures, Romania"},{"name":"Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540142 Targu Mures, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1080\/13625187.2021.1874337","article-title":"Dislocated intrauterine devices: Clinical presentations, diagnosis and management","volume":"26","author":"Tabatabaei","year":"2021","journal-title":"Eur. 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Womens Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/1752-1947-8-81","article-title":"Sigmoid colocolic fistula caused by intrauterine device migration: A case report","volume":"8","author":"Weerasekera","year":"2014","journal-title":"J. Med. Case Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1016\/j.ijsu.2007.02.006","article-title":"Surgical removal of an intrauterine device perforating the sigmoid colon: A case report","volume":"6","author":"Mederos","year":"2008","journal-title":"Int. J. Surg."},{"key":"ref_8","first-page":"70","article-title":"Intrauterine device migration to the urinary bladder causing sexual dysfunction: A case report","volume":"20","author":"Dimitropoulos","year":"2016","journal-title":"Hippokratia"},{"key":"ref_9","first-page":"3098","article-title":"Intrauterine Device Migration","volume":"174","author":"Lauridsen","year":"2012","journal-title":"Ugeskr. Laeger"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2147\/OAJC.S85546","article-title":"Intrauterine devices and risk of uterine perforation: Current perspectives","volume":"7","author":"Rowlands","year":"2016","journal-title":"Open Access J. Contracept."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1007\/s00192-011-1632-8","article-title":"Intrauterine device embedded into the bladder wall with stone formation: Laparoscopic removal is a minimally invasive alternative to open surgery","volume":"23","author":"Shin","year":"2012","journal-title":"Int. Urogynecol. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"rjt072","DOI":"10.1093\/jscr\/rjt072","article-title":"Surgical options for the retrieval of a migrated intrauterine contraceptive device","volume":"2013","author":"Subramanian","year":"2013","journal-title":"J. Surg. Case Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.contraception.2015.08.019","article-title":"Transmural migration and perforation of a levonorgestrel intrauterine system: A case report and review of the literature","volume":"93","author":"Ferguson","year":"2016","journal-title":"Contraception"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ijscr.2020.06.011","article-title":"Intrauterine device migration into the lumen of large bowel: A case report","volume":"72","author":"Aliukonis","year":"2020","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1136\/jfprhc-2013-100684","article-title":"Low-lying or malpositioned intrauterine devices and systems","volume":"40","author":"Golightly","year":"2014","journal-title":"J. Fam. Plann. Reprod. Health Care"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/9\/2227\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:32:06Z","timestamp":1760142726000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/9\/2227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,15]]},"references-count":15,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,9]]}},"alternative-id":["diagnostics12092227"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics12092227","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2022,9,15]]}}}