{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:09:36Z","timestamp":1792426176471,"version":"4.5.0"},"reference-count":53,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Helmholtz Zentrum M\u00fcnchen\u2014German Research Center for Environmental Health","award":["BA 4233\/4-1"],"award-info":[{"award-number":["BA 4233\/4-1"]}]},{"name":"Munich Center of Health Sciences, Ludwig-Maximilians-University","award":["BA 4233\/4-1"],"award-info":[{"award-number":["BA 4233\/4-1"]}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["BA 4233\/4-1"],"award-info":[{"award-number":["BA 4233\/4-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Siemens Healthcare","award":["BA 4233\/4-1"],"award-info":[{"award-number":["BA 4233\/4-1"]}]},{"name":"Open Access Publication Fund of the University of Freiburg","award":["BA 4233\/4-1"],"award-info":[{"award-number":["BA 4233\/4-1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Management of radiological incidental findings (IF) is of rising importance; however, psychosocial implications of IF reporting remain unclear. We compared long-term psychosocial effects between individuals who underwent whole-body magnetic resonance imaging (MRI) with and without reported IF, and individuals who did not undergo imaging. We used a longitudinal population-based cohort from Western Europe. Longitudinal analysis included three examinations (exam 1, 6 years prior to MRI; exam 2, MRI; exam 3, 4 years after MRI). Psychosocial outcomes included PHQ-9 (Patient Health Questionnaire), DEEX (Depression and Exhaustion Scale), PSS-10 (Perceived Stress Scale) and a Somatization Scale. Univariate analyses and adjusted linear mixed models were calculated. Among 855 included individuals, 25% (n = 212) underwent MRI and 6% (n = 50) had at least one reported IF. Compared to MRI participants, non-participants had a higher psychosocial burden indicated by PHQ-9 in exam 1 (3.3 \u00b1 3.3 vs. 2.5 \u00b1 2.3) and DEEX (8.6 \u00b1 4.7 vs. 7.7 \u00b1 4.4), Somatization Scale (5.9 \u00b1 4.3 vs. 4.8 \u00b1 3.8) and PSS-10 (14.7 \u00b1 5.7 vs. 13.7 \u00b1 5.3, all p &lt; 0.05) in exam 3. MRI participation without IF reporting was significantly associated with lower values of DEEX, PHQ-9 and Somatization Scale. There were no significant differences at the three timepoints between MRI participants with and without IF. In conclusion, individuals who voluntarily participated in whole-body MRI had less psychosocial burden and imaging and IF reporting were not associated with adverse long-term psychosocial consequences. However, due to the study design we cannot conclude that the MRI exam itself represented a beneficial intervention causing improvement in mental health scores.<\/jats:p>","DOI":"10.3390\/diagnostics12102356","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T20:58:47Z","timestamp":1664398727000},"page":"2356","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long-Term Psychosocial Consequences of Whole-Body Magnetic Resonance Imaging and Reporting of Incidental Findings in a Population-Based Cohort Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Dorina","family":"Korbmacher-B\u00f6ttcher","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Bamberg","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-0985","authenticated-orcid":false,"given":"Annette","family":"Peters","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany"},{"name":"Institute of Medical Information Sciences, Biometry and Epidemiology(IBE), Ludwig-Maximilians University, 80539 Munich, Germany"},{"name":"German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3387-5685","authenticated-orcid":false,"given":"Birgit","family":"Linkohr","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0221-311X","authenticated-orcid":false,"given":"Karl-Heinz","family":"Ladwig","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany"},{"name":"German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802 Munich, Germany"},{"name":"Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universit\u00e4t M\u00fcnchen (TUM), 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0935-6989","authenticated-orcid":false,"given":"Lars","family":"Schwettmann","sequence":"additional","affiliation":[{"name":"Institute of Health Economics and Health Care Management, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, 85764 Neuherberg, Germany"},{"name":"Department of Economics, Martin Luther University Halle-Wittenberg, 06099 Halle (Saale), Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Weckbach","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, 69126 Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1576-1481","authenticated-orcid":false,"given":"Christopher L.","family":"Schlett","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4788-2341","authenticated-orcid":false,"given":"Susanne","family":"Rospleszcz","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany"},{"name":"Institute of Medical Information Sciences, Biometry and Epidemiology(IBE), Ludwig-Maximilians University, 80539 Munich, Germany"},{"name":"German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 80802 Munich, 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