{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T07:36:09Z","timestamp":1762068969086,"version":"build-2065373602"},"reference-count":36,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Sichuan Medical Scientific Research Project Plan","award":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"],"award-info":[{"award-number":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"]}]},{"name":"Chengdu Health Commission Medical Scientific Research Project","award":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"],"award-info":[{"award-number":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"]}]},{"name":"Sichuan Provincial Health Commission Scientific Research Project","award":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"],"award-info":[{"award-number":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"]}]},{"name":"National Natural Science Foundation of China","award":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"],"award-info":[{"award-number":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"]}]},{"name":"Sichuan Science and Technology Program","award":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"],"award-info":[{"award-number":["S19001","2021024","21JP155","82120108015","82102020","82071874","81971586","2020YJ0029"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Cardiac complications are common in antiretroviral therapy-treated (ART-treated) acquired immune deficiency syndrome (AIDS) patients, and the incidence increases with age. Myocardial injury in ART-treated AIDS patients with a relatively longer disease duration has been evaluated. However, there is no relevant study on whether patients with a short AIDS duration have cardiac dysfunction. Thirty-seven ART-treated males with AIDS and eighteen healthy controls (HCs) were prospectively included for CMR scanning. Clinical data and laboratory examination results were collected. The ART-treated males with AIDS did not have significantly reduced biventricular ejection fraction, myocardial edema, or late gadolinium enhancement. Compared with the HCs, the biventricular volume parameters and left ventricle myocardial strain indices in ART-treated males with AIDS were not significantly reduced (all p &gt; 0.05). ART-treated males with AIDS were divided into subgroups according to their CD4+ T-cell counts (&lt;350 cells\/\u03bcL and \u2265350 cells\/\u03bcL) and duration of disease (1\u201312 months, 13\u201324 months, and 25\u201336 months). There was no significant decrease in left or right ventricular volume parameters or myocardial strain indices among the subgroups (all p &gt; 0.05). In Pearson correlation analysis, CD4+ T-cell counts were not significantly correlated with biventricular volume parameters or left ventricular myocardial strain indices. In conclusion, ART-treated males with AIDS receiving ART therapy with a short disease duration (less than 3 years) might not develop obvious cardiac dysfunction as evaluated by routine CMR, so it is reasonable to appropriately extend the interval between cardiovascular follow-ups to more than 3 years.<\/jats:p>","DOI":"10.3390\/diagnostics12102417","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T01:52:21Z","timestamp":1665193941000},"page":"2417","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Application of Cardiac Magnetic Resonance in ART-Treated AIDS Males with Short Disease Duration"],"prefix":"10.3390","volume":"12","author":[{"given":"Keke","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Fu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Department of Radiology, West China Second University Hospital, Sichuan University, 20# South Renmin Road, Chengdu 610017, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueqin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqiu","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianglin","family":"He","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianbiao","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Public Health Clinical Center of Chengdu, Chengdu 610061, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8437-9887","authenticated-orcid":false,"given":"Yingkun","family":"Guo","sequence":"additional","affiliation":[{"name":"Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Department of Radiology, West China Second University Hospital, Sichuan University, 20# South Renmin Road, Chengdu 610017, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jchf.2018.12.004","article-title":"Myocardial Dysfunction With Contemporary Management of HIV: Prevalence, Pathophysiology, and Opportunities for Prevention","volume":"7","author":"Grinspoon","year":"2019","journal-title":"JACC Heart Fail."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/0735-1097(88)90213-6","article-title":"Prevalent myocarditis at necropsy in the acquired immunodeficiency syndrome","volume":"11","author":"Anderson","year":"1988","journal-title":"J. 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