{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:48:01Z","timestamp":1760244481470,"version":"build-2065373602"},"reference-count":10,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:00:00Z","timestamp":1670889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Gastric MALToma is an extra-nodal marginal-type B-cell lymphoma. MALToma may occur secondary to chronic inflammation and autoimmunity. The most common gastrointestinal (GI) site of MALToma is the stomach, with approximately 50% of lesions occurring there. Synchronous upper and lower GI MALTomas rarely occur, with few cases reported. We present the case of a 67-year-old patient who presented asymptomatic and was found to have synchronous multifocal upper and lower GI MALTomas in the stomach, duodenum, terminal ileum, and sigmoid, which did not respond to H. Pylori eradication therapy.<\/jats:p>","DOI":"10.3390\/diagnostics12123150","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T02:22:41Z","timestamp":1670984561000},"page":"3150","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multiple Synchronous Mucosa-Associated Lymphoid Lymphomas Involving in the Stomach, Duodenum, Ileum, and Sigmoid"],"prefix":"10.3390","volume":"12","author":[{"given":"Chun-Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Yuan Lin Christian Hospital, Yuanlin City 510, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5936-7112","authenticated-orcid":false,"given":"Yang-Yuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Endoscopic Center, Changhua Christian Hospital, 3 Lane 138 Tai-An 2nd Street, Changhua City 500, Taiwan"},{"name":"Yuan Lin Branch, Department of Hospitality Management, MingDao University, Changhua City 523, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung-Fang","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Radiology, China Medical University, China Medical University Hospital, Taichung City 404, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1159\/000446576","article-title":"Synchronous Upper and Lower Gastrointestinal Mucosa-Associated Lymphoid Tissue Lymphomas","volume":"10","author":"McFarlane","year":"2016","journal-title":"Case Rep. Gastroenterol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1067\/mge.2003.334","article-title":"Simultaneous malt lymphoma of stomach, duodenum, and colon","volume":"58","author":"Isomoto","year":"2003","journal-title":"Gastrointest. Endosc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"204","DOI":"10.5217\/ir.2013.11.3.204","article-title":"Synchronous Primary Low-grade Mucosa-associated Lymphoid Tissue Lymphoma of Colon and Stomach","volume":"11","author":"Jeong","year":"2013","journal-title":"Intest. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"31707","DOI":"10.3402\/jchimp.v6.31707","article-title":"An unusual presentation of gastric mucosa-associated lymphoid tissue (MALT)-type lymphoma","volume":"6","author":"Shrestha","year":"2016","journal-title":"J. Community Hosp. Intern. Med. Perspect."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"85","DOI":"10.12701\/yujm.2019.00136","article-title":"Endoscopic features aiding the diagnosis of gastric mucosa-associated lymphoid tissue lymphoma","volume":"36","author":"Park","year":"2019","journal-title":"Yeungnam Univ. J. Med."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Ishikawa, E., Nakamura, M., Satou, A., Shimada, K., and Nakamura, S. (2022). Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma in the Gastrointestinal Tract in the Modern Era. Cancers, 14.","DOI":"10.3390\/cancers14020446"},{"key":"ref_7","first-page":"e37","article-title":"A Rare Case of MALT Lymphoma Underlying Ileocecal Intussusception","volume":"116","author":"Adams","year":"2016","journal-title":"J. Am. Osteopat. Assoc."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"491","DOI":"10.12659\/AJCR.902843","article-title":"Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Colon: A Case Report and a Literature Review","volume":"18","author":"Abbas","year":"2017","journal-title":"Am. J. Case Rep."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.4166\/kjg.2020.126","article-title":"Colonic Mucosa-associated Lymphoid Tissue Lymphoma Treated by Radiation Therapy: Re-port of a Case and Literature Review","volume":"76","author":"Zhou","year":"2020","journal-title":"Korean J. Gastroenterol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1072-7515(03)00002-4","article-title":"Management of gastrointestinal lymphoma","volume":"197","author":"Koniaris","year":"2003","journal-title":"J. Am. Coll. Surg."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/12\/3150\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:40:42Z","timestamp":1760146842000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/12\/12\/3150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,13]]},"references-count":10,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["diagnostics12123150"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics12123150","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2022,12,13]]}}}