{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:45:18Z","timestamp":1760147118818,"version":"build-2065373602"},"reference-count":85,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH grant","award":["R01EY030851","1853222\/2021192","R01EY030851"],"award-info":[{"award-number":["R01EY030851","1853222\/2021192","R01EY030851"]}]},{"name":"NSF DMS","award":["R01EY030851","1853222\/2021192","R01EY030851"],"award-info":[{"award-number":["R01EY030851","1853222\/2021192","R01EY030851"]}]},{"name":"NYEE Foundation grant","award":["R01EY030851","1853222\/2021192","R01EY030851"],"award-info":[{"award-number":["R01EY030851","1853222\/2021192","R01EY030851"]}]},{"name":"Challenge Grant award from Research to Prevent Blindness, NY","award":["R01EY030851","1853222\/2021192","R01EY030851"],"award-info":[{"award-number":["R01EY030851","1853222\/2021192","R01EY030851"]}]},{"name":"NIH grant","award":["R01EY030851","1853222\/2021192","R01EY030851"],"award-info":[{"award-number":["R01EY030851","1853222\/2021192","R01EY030851"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: The purpose of this study was to examine the changes in IOP, total macular and RNFL, ganglion cell layer (GCL) thickness, and aqueous humour flare in open angle glaucoma (OAG) patients before and 6 months after cataract surgery. Methods: This was a prospective observational case\u2013control age- and gender-matched study. Groups: 40 subjects in a controlled OAG (OAGc) group, 20 subjects in an uncontrolled OAG (OAGu) group, and 60 control group subjects. Examination: complete ophthalmic evaluation, IOP measurement, anterior and posterior segment Optical Coherence Tomography (OCT), and laser flare photometry before and 6 months postoperatively. Results: Six months postoperatively IOP decreased in all groups. An increase in macular thickness was found postoperatively in all groups. Preoperative aqueous humour flare was higher in the OAGc group than in the control group. After cataract surgery, aqueous humour flare was higher in the control group compared to the preoperative result. Conclusions: Changes in IOP following cataract surgery were strongly negatively correlated with preoperative IOP. An increase in macular thickness was observed 6 months postoperatively in all groups. Aqueous humour flare did not differ in OAGc and OAGu groups pre- and postoperatively but significantly increased in the control group postoperatively.<\/jats:p>","DOI":"10.3390\/diagnostics13020244","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T06:38:27Z","timestamp":1673246307000},"page":"244","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Changes in Macular Thickness after Cataract Surgery in Patients with Open Angle Glaucoma"],"prefix":"10.3390","volume":"13","author":[{"given":"Giedre","family":"Pakuliene","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7277-6014","authenticated-orcid":false,"given":"Neda","family":"Rylskyte","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loreta","family":"Kuzmiene","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent","family":"Siesky","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Verticchio","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alon","family":"Harris","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2660-7922","authenticated-orcid":false,"given":"Ingrida","family":"Januleviciene","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"European Glaucoma Society EGS Foundation (2020). Terminology and Guidelines for Glaucoma, 5th Edition. Br. J. Ophthalmol., 105, 1\u2013170.","DOI":"10.1136\/bjophthalmol-2021-egsguidelines"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1001\/jama.2014.3192","article-title":"The Pathophysiology and Treatment of Glaucoma: A Review","volume":"311","author":"Weinreb","year":"2015","journal-title":"J. Am. Med. Assoc. JAMA"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000458482","article-title":"Achievements and Limits of Current Medical Therapy of Glaucoma","volume":"59","author":"Kalouda","year":"2017","journal-title":"Dev. Ophthalmol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S0140-6736(17)30544-5","article-title":"Cataracts","volume":"390","author":"Liu","year":"2017","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.jcrs.2013.11.033","article-title":"Ocular comorbidity and self-assessed visual function after cataract surgery","volume":"40","author":"Grimfors","year":"2014","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_6","first-page":"887","article-title":"Glaucoma is second leading cause of blindness globally","volume":"82","author":"Kingman","year":"2004","journal-title":"Bull. World Health Organ."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s10792-016-0230-7","article-title":"Effect of intraoperative factors on IOP reduction after phacoemulsification","volume":"37","author":"DeVience","year":"2017","journal-title":"Int. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jcrs.2011.06.037","article-title":"Association of biometric factors with anterior chamber angle widening and intraocular pressure reduction after uneventful phacoemulsification for cataract","volume":"38","author":"Huang","year":"2012","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12886-019-1157-3","article-title":"Long term effect of phacoemulsification on intraocular pressure in patients with medically controlled primary open-angle glaucoma","volume":"19","author":"Majstruk","year":"2019","journal-title":"BMC Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/OPX.0b013e31827ce224","article-title":"Preoperative factors associated with IOP reduction after cataract surgery","volume":"90","author":"Guan","year":"2013","journal-title":"Optom. Vis. Sci."},{"key":"ref_11","first-page":"11","article-title":"Intraocular pressure after phacoemulsification in patients with uncontrolled primary open angle glaucoma","volume":"7","author":"Iancu","year":"2014","journal-title":"J. Med. Life"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e259","DOI":"10.1097\/IJG.0000000000000271","article-title":"Anterior chamber angle and intraocular pressure changes after phacoemulsification: A comparison between eyes with closed-angle and open-angle glaucoma","volume":"25","author":"Siak","year":"2016","journal-title":"J. Glaucoma"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e12881","DOI":"10.1097\/MD.0000000000012881","article-title":"Glaucoma severity and intraocular pressure reduction after cataract surgery in eyes with medically controlled glaucoma","volume":"97","author":"Yoo","year":"2018","journal-title":"Medicine"},{"key":"ref_14","first-page":"1374","article-title":"Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma","volume":"10","author":"Turati","year":"2017","journal-title":"Int. J. Ophthalmol."},{"key":"ref_15","first-page":"1","article-title":"Predictors of intraocular pressure after phacoemulsification in primary open-angle glaucoma eyes with wide versus narrower angles (an American ophthalmological society thesis)","volume":"115","author":"Lin","year":"2017","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ajo.2013.02.003","article-title":"Ocular Biometric Parameters Associated With Intraocular Pressure Reduction After Cataract Surgery in Normal Eyes","volume":"156","author":"Yang","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"9390586","DOI":"10.1155\/2019\/9390586","article-title":"Intraocular pressure and anterior segment morphometry changes after uneventful phacoemulsification in type 2 diabetic and nondiabetic patients","volume":"2019","author":"Beato","year":"2019","journal-title":"J. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e12023","DOI":"10.1097\/MD.0000000000012023","article-title":"Changes of intraocular pressure after cataract surgery in myopic and emmetropic patients","volume":"97","author":"Lv","year":"2018","journal-title":"Medicine"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1097\/OPX.0000000000000553","article-title":"Biometric and intraocular pressure change after cataract surgery","volume":"92","author":"Bilak","year":"2015","journal-title":"Optom. Vis. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1038\/eye.2015.141","article-title":"Lens parameters as predictors of intraocular pressure changes after phacoemulsification","volume":"29","author":"Moghimi","year":"2015","journal-title":"Eye"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.3346\/jkms.2019.34.e47","article-title":"Effect of phacoemulsification on intraocular pressure in healthy subjects and Glaucoma patients","volume":"34","author":"Baek","year":"2019","journal-title":"J. Korean Med. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1167\/iovs.16-19384","article-title":"Lens position parameters as predictors of intraocular pressure reduction after cataract surgery in glaucomatous versus nonglaucomatous eyes","volume":"57","author":"Coh","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3341\/kjo.2012.26.2.97","article-title":"Anterior chamber configuration changes after cataract surgery in eyes with glaucoma","volume":"26","author":"Kim","year":"2012","journal-title":"Korean J. Ophthalmol."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Kim, Y.C., Sung, M.S., Heo, H., and Park, S.W. (2016). Anterior segment configuration as a predictive factor for refractive outcome after cataract surgery in patients with glaucoma. BMC Ophthalmol., 16.","DOI":"10.1186\/s12886-016-0359-1"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/cne.903000103","article-title":"Topography of ganglion cells in human retina","volume":"300","author":"Curcio","year":"1990","journal-title":"J. Comp. Neurol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5005\/jp-journals-10008-1207","article-title":"Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields","volume":"10","author":"Mota","year":"2016","journal-title":"J. Curr. Glaucoma Pract."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5005\/jp-journals-10008-1154","article-title":"Macular Thickness Variability in Primary Open Angle Glaucoma Patients using Optical Coherence Tomography","volume":"8","author":"Sharma","year":"2014","journal-title":"J. Curr. Glaucoma Pract."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Ikegami, Y., Takahashi, M., and Amino, K. (2020). Evaluation of choroidal thickness, macular thickness, and aqueous flare after cataract surgery in patients with and without diabetes: A prospective randomized study. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-020-01371-7"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1167\/iovs.18-25864","article-title":"Age-related alterations in retinal tissue perfusion and volumetric vessel density","volume":"60","author":"Lin","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"5713","DOI":"10.1167\/iovs.17-22865","article-title":"Optical coherence tomography angiography macular and peripapillary vessel perfusion density in healthy subjects, glaucoma suspects, and glaucoma patients","volume":"58","author":"Triolo","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/IJG.0000000000000964","article-title":"Optical Coherence Tomography Angiography Macular Vascular Density Measurements and the Central 10-2 Visual Field in Glaucoma","volume":"27","author":"Penteado","year":"2018","journal-title":"J. Glaucoma"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1167\/iovs.17-21440","article-title":"Underlying Microstructure of Parapapillary Deep-Layer Capillary Dropout Identified by Optical Coherence Tomography Angiography","volume":"58","author":"Lee","year":"2017","journal-title":"Investig. Opthalmology Vis. Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1136\/bjophthalmol-2017-310180","article-title":"Regional vascular density\u2014Visual field sensitivity relationship in glaucoma according to disease severity","volume":"101","author":"Shin","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1136\/bjophthalmol-2016-309816","article-title":"Swept-source OCT angiography imaging of the macular capillary network in glaucoma","volume":"102","author":"Akil","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1136\/bjophthalmol-2016-309642","article-title":"Peripapillary perfused capillary density in primary open-angle glaucoma across disease stage: An optical coherence tomography angiography study","volume":"101","author":"Geyman","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Krizanovic, A., Bjelos, M., Busic, M., Kuzmanovic Elabjer, B., Rak, B., and Vukojevic, N. (2021). Macular perfusion analysed by optical coherence tomography angiography after uncomplicated phacoemulsification: Benefits beyond restoring vision. BMC Ophthalmol., 21.","DOI":"10.1186\/s12886-021-01837-2"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s10792-009-9310-2","article-title":"Laser flare photometry: A noninvasive, objective, and quantitative method to measure intraocular inflammation","volume":"30","author":"Herbort","year":"2010","journal-title":"Int. Ophthalmol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1007\/s10792-021-01779-0","article-title":"Laser flare and cell photometry to measure inflammation after cataract surgery: A tool to predict the risk of cystoid macular edema","volume":"41","author":"Coassin","year":"2021","journal-title":"Int. Ophthalmol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.preteyeres.2012.10.004","article-title":"A Contemporary Concept of the Blood-Aqueous Barrier","volume":"23","author":"Freddo","year":"2013","journal-title":"Prog Retin Eye Res"},{"key":"ref_40","first-page":"379","article-title":"Quantitative assessment of aqueous flare: The effect of age and pupillary dilation","volume":"33","author":"Ruiz","year":"2022","journal-title":"Ophthalmic Surg. Lasers"},{"key":"ref_41","first-page":"2878","article-title":"Correlations between laser flare measurements and anterior chamber protein concentrations","volume":"33","author":"Shah","year":"1992","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/bjo.75.6.348","article-title":"Measurement of aqueous cells and flare in normal","volume":"75","author":"Shah","year":"1991","journal-title":"Br. J. Ophthalmol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12348-018-0165-4","article-title":"Laser flare photometry: A cost-effective method for early detection of endophthalmitis after intravitreal injection of anti-VEGF agents","volume":"8","author":"Lages","year":"2018","journal-title":"J. Ophthalmic Inflamm. Infect."},{"key":"ref_44","first-page":"449","article-title":"Laser flare photometry and its use in uveitis","volume":"7","author":"Herbort","year":"2014","journal-title":"Expert Rev. Ophthalmol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1080\/09273948.2019.1643029","article-title":"Effect of Tropicamide on Laser Flare Meter Measurements in Patients with Pseudoexfoliation","volume":"28","author":"Karaca","year":"2019","journal-title":"Ocul. Immunol. Inflamm."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: An open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.jcrs.2014.06.001","article-title":"Lens-based glaucoma surgery: Using cataract surgery to reduce intraocular pressure","volume":"40","author":"Brown","year":"2014","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/ICU.0000000000000224","article-title":"Glaucoma and cataract surgery: Two roads merging into one","volume":"27","author":"Shah","year":"2016","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/ICU.0b013e328332f562","article-title":"Cataract surgery and glaucoma","volume":"21","author":"Vizzeri","year":"2010","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_50","first-page":"CD008671","article-title":"Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma","volume":"2015","author":"Zhang","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.preteyeres.2018.01.003","article-title":"Cataract, phacoemulsification and intraocular pressure: Is the anterior segment anatomy the missing piece of the puzzle?","volume":"64","author":"Lin","year":"2018","journal-title":"Prog. Retin. Eye Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.tjo.2016.01.003","article-title":"Macular thickness analysis for glaucoma diagnosis and management","volume":"6","author":"Gupta","year":"2016","journal-title":"Taiwan J. Ophthalmol."},{"key":"ref_53","first-page":"1","article-title":"Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets","volume":"12","author":"Freude","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_54","first-page":"687","article-title":"Effect of simulated dynamic intraocular pressure on retinal thickness measured by optical coherence tomography after cataract surgery","volume":"5","author":"Chen","year":"2012","journal-title":"Int. J. Ophthalmol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3341\/kjo.2017.31.1.39","article-title":"Immediate Postoperative Intraocular Pressure Adjustment Reduces Risk of Cystoid Macular Edema after Uncomplicated Micro Incision Coaxial Phacoemulsification Cataract Surgery","volume":"31","author":"Jarstad","year":"2017","journal-title":"Korean J. Ophthalmol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"7419470","DOI":"10.1155\/2019\/7419470","article-title":"Early macular angiography among patients with glaucoma, ocular hypertension, and normal subjects","volume":"2019","author":"Chao","year":"2019","journal-title":"J. Ophthalmol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MD.0000000000010355","article-title":"New observation of microcystic macular edema as a mild form of cystoid macular lesions after standard phacoemulsification","volume":"97","author":"Yoon","year":"2018","journal-title":"Medicine"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Wang, Z., Wang, E., and Chen, Y. (2020). Transient reduction in macular deep capillary density on optical coherence tomography angiography after phacoemulsification surgery in diabetic patients. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-020-01605-8"},{"key":"ref_59","first-page":"CD010516","article-title":"Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery","volume":"2017","author":"Juthani","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_60","first-page":"3459156","article-title":"Visual Acuity, Retinal Sensitivity, and Macular Thickness Changes in Diabetic Patients without Diabetic Retinopathy after Cataract Surgery","volume":"2017","author":"Pfeifer","year":"2017","journal-title":"J. Diabetes Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0144156","article-title":"Correlation of aging and segmental choroidal thickness measurement using swept source optical coherence tomography in healthy eyes","volume":"10","author":"Wakatsuki","year":"2015","journal-title":"PLoS ONE"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1097\/IAE.0000000000001262","article-title":"Changes in choroidal thickness in and outside the macula after hemodialysis in patients with end-stage renal disease","volume":"37","author":"Chang","year":"2017","journal-title":"Retina"},{"key":"ref_63","first-page":"1","article-title":"Assessment of Choroidal Thickness and Volume During the Water Drinking Test By Swept-Source Optical Coherence Tomography","volume":"120","author":"Mansouri","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1136\/bjophthalmol-2016-309881","article-title":"Anterior but not posterior choroid changed before and during Valsalva manoeuvre in healthy Chinese: A UBM and SS-OCT study","volume":"101","author":"Li","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e21007","DOI":"10.1097\/MD.0000000000021007","article-title":"Changes of retinal and choroidal capillary blood flow in macula after an acute intraocular pressure elevation","volume":"99","author":"Ma","year":"2020","journal-title":"Medicine"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Gudauskien\u0117, G., Povilaityt\u0117, I., \u0160epetauskien\u0117, E., and \u017daliunien\u0117, D. (2020). Phacoemulsification Induced Changes of Choroidal Thickness in Eyes with Age-Related Macular Degeneration. Medicina, 56.","DOI":"10.3390\/medicina56050252"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Chen, H., Wu, Z., Chen, Y., He, M., and Wang, J. (2018). Short-term changes of choroidal vascular structures after phacoemulsification surgery. BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0749-7"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s10792-018-0882-6","article-title":"Anterior segment ultrasound biomicroscopy image analysis using ImageJ software: Intra-observer repeatability and inter-observer agreement","volume":"39","author":"Qureshi","year":"2019","journal-title":"Int. Ophthalmol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1007\/s10792-018-0918-y","article-title":"Changes in choroidal thickness following trabeculectomy and its correlation with the decline in intraocular pressure","volume":"39","author":"Silva","year":"2019","journal-title":"Int. Ophthalmol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/aos.13057","article-title":"Changes in choroidal thickness after intraocular pressure reduction following trabeculectomy","volume":"94","author":"Kadziauskiene","year":"2016","journal-title":"Acta Ophthalmol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1001\/jamaophthalmol.2019.0019","article-title":"Analysis of a Systematic Review about Blue Light-Filtering Intraocular Lenses for Retinal Protection: Understanding the Limitations of the Evidence","volume":"137","author":"Downie","year":"2019","journal-title":"JAMA Ophthalmol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1136\/bjophthalmol-2020-317038","article-title":"OCT angiography measured changes in the foveal avascular zone area after glaucoma surgery","volume":"106","author":"Shoji","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"10143","DOI":"10.1038\/s41598-018-28530-7","article-title":"Objective evaluation of size and shape of superficial foveal avascular zone in normal subjects by optical coherence tomography angiography","volume":"8","author":"Shiihara","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.joco.2017.06.004","article-title":"The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers","volume":"29","author":"Ghassemi","year":"2017","journal-title":"J. Curr. Ophthalmol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Choi, J., Kwon, J., Shin, J.W., Lee, J., Lee, S., and Kook, M.S. (2017). Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0184948"},{"key":"ref_76","first-page":"2026","article-title":"Damage to the blood-aqueous barrier in eyes with primary angle closure glaucoma","volume":"16","author":"Kong","year":"2010","journal-title":"Mol. Vis."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1600-0420.1997.tb00251.x","article-title":"Quantitative determination of aqueous flare and cells in healthy eyes","volume":"75","author":"Hartikainen","year":"1997","journal-title":"Acta Ophthalmol. Scand."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2147\/OPTH.S237405","article-title":"Measuring Anterior Chamber Inflammation After Cataract Surgery: A Review of the Literature Focusing on the Correlation with Cystoid Macular Edema","volume":"14","author":"Iannetta","year":"2020","journal-title":"Clin. Ophthalmol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1080\/09273948.2018.1449867","article-title":"Application of Laser Flare Photometry in the Quantification of Blood\u2013Aqueous Barrier Breakdown after Micro-incision Vitrectomy Application of Laser Flare Photometry in the Quanti fi cation of Blood\u2013Aqueous Barrier Breakdown after Micro-incision Vitrec","volume":"27","author":"Agarwal","year":"2018","journal-title":"Ocul. Immunol. Inflamm."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1007\/s12325-020-01383-1","article-title":"Persistence of Inflammation After Uncomplicated Cataract Surgery: A 6-Month Laser Flare Photometry Analysis","volume":"37","author":"Coassin","year":"2020","journal-title":"Adv. Ther."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s10792-016-0169-8","article-title":"Anterior chamber aqueous flare, pseudoexfoliation syndrome, and glaucoma","volume":"36","author":"Kahloun","year":"2016","journal-title":"Int. Ophthalmol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1136\/bjo.2007.120535","article-title":"Objective assessment of intraocular flare after cataract surgery with combined primary posterior capsulorhexis and posterior optic buttonholing in adults","volume":"91","author":"Stifter","year":"2007","journal-title":"Br. J. Ophthalmol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/sj.eye.6702542","article-title":"The effects of prostaglandin analogues on the blood aqueous barrier and corneal thickness of phakic patients with primary open-angle glaucoma and ocular hypertension","volume":"22","author":"Arcieri","year":"2008","journal-title":"Eye"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1089\/jop.2016.0128","article-title":"Assessment of the Anterior Chamber Flare and Macular Thickness in Patients Treated with Topical Antiglaucomatous Drugs","volume":"33","author":"Selen","year":"2017","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1159\/000079472","article-title":"Prostaglandin analogs and blood-aqueous barrier integrity: A flare cell meter study","volume":"218","author":"Cellini","year":"2004","journal-title":"Ophthalmologica"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/2\/244\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:04:23Z","timestamp":1760119463000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/2\/244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,9]]},"references-count":85,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["diagnostics13020244"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics13020244","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2023,1,9]]}}}