{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T10:36:34Z","timestamp":1784630194570,"version":"3.55.0"},"reference-count":27,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Despite recent developments, evaluation of peripheral pulmonary lesions (PPL) remains clinically challenging, and the diagnostic yield of many image-guided and bronchoscopy methods is still poor. Furthermore, complications from such procedures, such as pneumothorax and airway hemorrhage, are a major concern. Recently launched robotic-assisted bronchoscopy (RAB) platforms are still in the early exploration stage and may provide another tool for achieving PPL evaluation. We present our experience here as a retrospective cohort study describing the 12-month diagnostic yield with the shape-sensing Ion\u2122 platform for minimally invasive peripheral lung biopsy. The study describes forty-two patients undergoing shape sensing robotic-assisted bronchoscopy (ssRAB) at our institute. The early performance trend reveals a lesion localization of 100% and an overall 12-month diagnostic yield of 88.10%. The diagnostic yield for lesions less than 20 mm was 76% and for lesions greater than 20 mm was 100%. We also report our complication profile; we noted no pneumothoraces, excessive bleeding, or post-operative complications. In comparison to traditional bronchoscopy and image-guided modalities, our experience shows that ssRAB can be utilized successfully to travel to extremely small peripheral lesions with a higher diagnostic yield and better safety profile.<\/jats:p>","DOI":"10.3390\/diagnostics13061049","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T01:31:41Z","timestamp":1678411901000},"page":"1049","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The Use of Robotic-Assisted Bronchoscopy in the Diagnostic Evaluation of Peripheral Pulmonary Lesions: A Paradigm Shift"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1795-7517","authenticated-orcid":false,"given":"Hiba","family":"Hammad Altaq","sequence":"first","affiliation":[{"name":"Department of Pulmonary & Critical Care, University of Oklahoma, Oklahoma City, OK 73019, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miloni","family":"Parmar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Oklahoma, Oklahoma City, OK 73019, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3845-875X","authenticated-orcid":false,"given":"Talal","family":"Syed Hussain","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, University of Oklahoma, Oklahoma City, OK 73019, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9427-6504","authenticated-orcid":false,"given":"Daouk J.","family":"Salim","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, University of Oklahoma, Oklahoma City, OK 73019, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawad A.","family":"Chaudry","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, University of Oklahoma, Oklahoma City, OK 73019, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"National Lung Screening Trial Research Team, Aberle, D.R., Adams, A.M., Berg, C.D., Black, W.C., Clapp, J.D., Fagerstrom, R.M., Gareen, I.F., Gatsonis, C., and Marcus, P.M. 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